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    TPP1 Tpp1p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 855188, updated on 21-Jan-2012
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    Summary

    Gene symbol
    TPP1
    Gene description
    Tpp1p
    Primary source
    SGD:S000004765
    Locus tag
    YMR156C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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    Genomic context

    Sequence :
    Chromosome: XIII; NC_001145.3 (570300..571016, complement)
    See TPP1 in MapViewer

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Rim13p Neighboring gene hypothetical protein Neighboring gene Aim36p Neighboring gene Mrps8p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Genetic interactions between HNT3/Aprataxin and RAD27/FEN1 suggest parallel pathways for 5' end processing during base excision repair. Daley JM, et al. DNA Repair (Amst), 2010 Jun 4. PMID 20399152.
    2. The genetic landscape of a cell. Costanzo M, et al. Science, 2010 Jan 22. PMID 20093466.
    3. Investigations on the role of base excision repair and non-homologous end-joining pathways in sodium selenite-induced toxicity and mutagenicity in Saccharomyces cerevisiae. Mániková D, et al. Mutagenesis, 2010 Mar. PMID 19955329.
    4. Functional organization of the S. cerevisiae phosphorylation network. Fiedler D, et al. Cell, 2009 Mar 6. PMID 19269370.
    5. Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Collins SR, et al. Nature, 2007 Apr 12. PMID 17314980.

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:35331 BioGRID:35297 ADE17    BioGRID  PubMed Negative Genetic 
    BioGRID:35331 BioGRID:34020 APN1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35331 BioGRID:32679 APN2    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35331 BioGRID:35231 BUB2    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35331 BioGRID:32969 CHK1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35331 BioGRID:35377 CLN1    BioGRID  PubMed Negative Genetic 
    BioGRID:35331 BioGRID:35989 DDC1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35331 BioGRID:31961 DUN1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35331 BioGRID:31172 FAB1    BioGRID  PubMed Positive Genetic 
    BioGRID:35331 BioGRID:34648 HNT3    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35331 BioGRID:33729 MAD2    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35331 BioGRID:31458 MDL1    BioGRID  PubMed Negative Genetic 
    BioGRID:35331 BioGRID:31554 MEC3    BioGRID  PubMed Synthetic Lethality 
    BioGRID:35331 BioGRID:33579 MNN11    BioGRID  PubMed Positive Genetic 
    BioGRID:35331 BioGRID:30926 MRC1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35331 BioGRID:32170 PDS1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35331 BioGRID:36155 RAD1    BioGRID  PubMed Synthetic Growth Defect; Synthetic Rescue 
    BioGRID:35331 BioGRID:34751 RAD17    BioGRID  PubMed Synthetic Rescue 
    BioGRID:35331 BioGRID:36926 RAD24    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35331 BioGRID:35137 RAD52    BioGRID  PubMed Synthetic Lethality 
    BioGRID:35331 BioGRID:36030 RAD53    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35331 BioGRID:32270 RAD9    BioGRID  PubMed Synthetic Lethality 
    BioGRID:35331 BioGRID:31627 RPS22B    BioGRID  PubMed Negative Genetic 
    BioGRID:35331 BioGRID:32143 RRP1    BioGRID  PubMed Negative Genetic 
    BioGRID:35331 BioGRID:36588 RTT107    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35331 BioGRID:35368 SGS1    BioGRID  PubMed Negative Genetic 
    BioGRID:35331 BioGRID:32011 SIT4    BioGRID  PubMed Positive Genetic 
    BioGRID:35331 BioGRID:35109 SML1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35331 BioGRID:33308 SPT4    BioGRID  PubMed Negative Genetic 
    BioGRID:35331 BioGRID:32616 TEL1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35331 BioGRID:35586 TEX1    BioGRID  PubMed Negative Genetic 
    BioGRID:35331 BioGRID:35567 TOF1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35331 BioGRID:31421 YLR152C    BioGRID  PubMed Negative Genetic 
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    General gene information

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    polynucleotide 3'-phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    polynucleotide 3'-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    polynucleotide 3'-phosphatase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    DNA repair IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    DNA repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
    		  
    nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Names
    Tpp1p
    NP_013877.1
    • DNA 3'-phosphatase that functions in repair of endogenous damage of double-stranded DNA, activity is specific for removal of 3' phosphates at strand breaks; has similarity to the l-2-haloacid dehalogenase superfamily
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3

      Range
      570300..571016, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182659.1 → NP_013877.1  Tpp1p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q03796
      Conserved Domains (1) summary
      TIGR01664
      Location:11 – 237
      Blast Score: 489
      DNA-3'-Pase; DNA 3'-phosphatase
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006946.2 DAA10051.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    Q03796.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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