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    CIN4 Cin4p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 855169, updated on 4-Feb-2012
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    Summary

    Gene symbol
    CIN4
    Gene description
    Cin4p
    Primary source
    SGD:S000004746
    Locus tag
    YMR138W
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    GTP1; UGX1
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    Genomic context

    Sequence :
    Chromosome: XIII; NC_001145.3 (545155..545730)
    See CIN4 in MapViewer

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Gat2p Neighboring gene Pso2p Neighboring gene Rim11p Neighboring gene Sip5p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. The genetic landscape of a cell. Costanzo M, et al. Science, 2010 Jan 22. PMID 20093466.
    2. Distinct roles for Khd1p in the localization and expression of bud-localized mRNAs in yeast. Hasegawa Y, et al. RNA, 2008 Nov. PMID 18805955.
    3. Epistatic buffering of fitness loss in yeast double deletion strains. Jasnos L, et al. Nat Genet, 2007 Apr. PMID 17322879.
    4. Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Collins SR, et al. Nature, 2007 Apr 12. PMID 17314980.
    5. Modeling complex genetic interactions in a simple eukaryotic genome: actin displays a rich spectrum of complex haploinsufficiencies. Haarer B, et al. Genes Dev, 2007 Jan 15. PMID 17167106.

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:35315 BioGRID:31107 ACT1    BioGRID  PubMed Synthetic Haploinsufficiency 
    BioGRID:35315 BioGRID:31382 AHP1    BioGRID  PubMed Two-hybrid 
    BioGRID:35315 BioGRID:35861 ARC35    BioGRID  PubMed Two-hybrid 
    BioGRID:35315 BioGRID:36562 ARP1    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:33074 ATG1    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:31912 ATG9    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:35942 ATP15    BioGRID  PubMed Synthetic Lethality 
    BioGRID:35315 BioGRID:34230 BAS1    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:30954 BIK1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:35315 BioGRID:33440 BUB1    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:34429 BUB3    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:35376 CIK1    BioGRID  PubMed Positive Genetic 
    BioGRID:35315 BioGRID:34734 CIN1    BioGRID  PubMed Dosage Rescue; Synthetic Growth Defect; Synthetic Rescue 
    BioGRID:35315 BioGRID:35922 CIN2    BioGRID  PubMed Two-hybrid 
    BioGRID:35315 BioGRID:36668 CIN8    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:35315 BioGRID:34272 CTR9    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:35442 CUE1    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:31945 CYK3    BioGRID  PubMed Two-hybrid 
    BioGRID:35315 BioGRID:35351 DDR48    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:35479 DYN3    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:35676 GIM3    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:35315 BioGRID:36728 GIM4    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:35315 BioGRID:35049 GIM5    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:35315 BioGRID:34345 GPM3    BioGRID  PubMed Two-hybrid 
    BioGRID:35315 BioGRID:34469 GYP1    BioGRID  PubMed Two-hybrid 
    BioGRID:35315 BioGRID:32665 HEK2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:35315 BioGRID:35474 JNM1    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:31266 LDB18    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:35681 LSM7    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:35875 LYS9    BioGRID  PubMed Two-hybrid 
    BioGRID:35315 BioGRID:35276 MUB1    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:36009 NIP100    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:35315 BioGRID:32203 NUM1    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:33081 NUP49    BioGRID  PubMed Two-hybrid 
    BioGRID:35315 BioGRID:33320 PAC10    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:35315 BioGRID:33344 PCP1    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:33582 PFD1    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:36465 PIH1    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:34654 RBL2    BioGRID  PubMed Synthetic Lethality 
    BioGRID:35315 BioGRID:36153 RMI1    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:36922 RPH1    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:35537 RPL18B    BioGRID  PubMed Two-hybrid 
    BioGRID:35315 BioGRID:36101 RPL21B    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:36574 RPL42B    BioGRID  PubMed Two-hybrid 
    BioGRID:35315 BioGRID:31921 RPO21    BioGRID  PubMed Positive Genetic 
    BioGRID:35315 BioGRID:32887 RPS9B    BioGRID  PubMed Two-hybrid 
    BioGRID:35315 BioGRID:32143 RRP1    BioGRID  PubMed Two-hybrid 
    BioGRID:35315 BioGRID:33181 SGF73    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:36698 SPF1    BioGRID  PubMed Positive Genetic 
    BioGRID:35315 BioGRID:35357 SPT21    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:31320 STU2    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:36026 TGS1    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:36290 THI22    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:35056 TUB1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:35315 BioGRID:31109 TUB2    BioGRID  PubMed Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:35315 BioGRID:35081 TUB3    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35315 BioGRID:32841 YBR141C    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:32978 YBR284W    BioGRID  PubMed Two-hybrid 
    BioGRID:35315 BioGRID:36916 YER163C    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:33336 YGR093W    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:31469 YKE2    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:35315 BioGRID:35281 YKU80    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:31421 YLR152C    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:36525 YNG2    BioGRID  PubMed Synthetic Lethality 
    BioGRID:35315 BioGRID:35705 YNL122C    BioGRID  PubMed Negative Genetic 
    BioGRID:35315 BioGRID:32441 YRA1    BioGRID  PubMed Two-hybrid 
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    General gene information

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    GTP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    protein folding IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    small GTPase mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    intracellular IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Names
    Cin4p
    NP_013858.1
    • GTP-binding protein involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl; regulated by the GTPase-activating protein, Cin2p, the human retinitis pigmentosa 2 (RP2) homolog
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3

      Range
      545155..545730
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182640.1 → NP_013858.1  Cin4p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P39110
      Conserved Domains (1) summary
      cd00878
      Location:18 – 185
      Blast Score: 434
      Arf_Arl; ADP-ribosylation factor(Arf)/Arf-like (Arl) small GTPases
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006946.2 DAA10035.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    P39110.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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