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    SOK2 Sok2p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 855030, updated on 5-May-2013
    Gene symbol
    SOK2
    Gene description
    Sok2p
    Primary source
    SGD:S000004618
    Locus tag
    YMR016C
    Gene type
    protein coding
    RNA name
    Sok2p
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Location :
    chromosome: XIII
    Sequence :
    Chromosome: XIII; NC_001145.3 (303236..305593, complement)
    See SOK2 in MapViewer

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Bud22p Neighboring gene C-22 sterol desaturase Neighboring gene Spo20p Neighboring gene hypothetical protein

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. Saccharomyces cerevisiae genetics predicts candidate therapeutic genetic interactions at the mammalian replication fork. van Pel DM, et al. G3 (Bethesda), 2013 Feb. PMID 23390603.
    2. Global gene deletion analysis exploring yeast filamentous growth. Ryan O, et al. Science, 2012 Sep 14. PMID 22984072.
    3. Genome-wide analysis to identify pathways affecting telomere-initiated senescence in budding yeast. Chang HY, et al. G3 (Bethesda), 2011 Aug. PMID 22384331.
    4. Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Sharifpoor S, et al. Genome Res, 2012 Apr. PMID 22282571.
    5. New insight into the role of the Cdc34 ubiquitin-conjugating enzyme in cell cycle regulation via Ace2 and Sic1. Cocklin R, et al. Genetics, 2011 Mar. PMID 21196523.

    See all (28) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:35187 BioGRID:36693 ANP1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:35988 APL5    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:32183 ARO1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:31358 ARP6    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:34535 ARP8    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:33937 ASH1    BioGRID  PubMed Phenotypic Suppression; Synthetic Growth Defect 
    BioGRID:35187 BioGRID:34509 AZF1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:34957 BCY1    BioGRID  PubMed PCA 
    BioGRID:35187 BioGRID:35041 CAC2    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:33817 CBF1    BioGRID  PubMed Positive Genetic 
    BioGRID:35187 BioGRID:31825 CDC13    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35187 BioGRID:31579 CDC3    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:32107 CDC34    BioGRID  PubMed Synthetic Lethality 
    BioGRID:35187 BioGRID:32219 CDC37    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:35187 BioGRID:31066 CDC50    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:33121 CEG1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:31371 CHA4    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:34431 CIN5    BioGRID  PubMed Positive Genetic 
    BioGRID:35187 BioGRID:31725 CLN3    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:31692 CNA1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:32356 CPR5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:35187 BioGRID:35254 CTF18    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:36001 CTI6    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:34085 ELM1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:34635 ESA1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:31502 EST1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35187 BioGRID:34764 FIT3    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:35011 FLO11    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:35187 BioGRID:36854 FLO8    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:35187 BioGRID:33297 FMP48    BioGRID  PubMed Positive Genetic 
    BioGRID:35187 BioGRID:31270 FPS1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:36041 FRK1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:32682 FUS3    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:35635 GCR2    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:32414 GGA1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:32559 GIN4    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:34469 GYP1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:34313 HAL9    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:35923 HSP82    BioGRID  PubMed Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:35187 BioGRID:35621 IES2    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:34101 IXR1    BioGRID  PubMed Positive Genetic 
    BioGRID:35187 BioGRID:35944 KAR9    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35187 BioGRID:32636 KIP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:35187 BioGRID:31233 KNS1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:31528 LCB5    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:32002 MBP1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:33890 MCM22    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:33060 MDS3    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:36154 MET12    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:34863 MET18    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:35683 MFA2    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:31878 MFG1    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:35187 BioGRID:30940 MGR1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:33212 MIG1    BioGRID  PubMed Positive Genetic 
    BioGRID:35187 BioGRID:30926 MRC1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:35209 MSN2    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:35187 BioGRID:35194 MSS1    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:35187 BioGRID:33004 MTO1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:35762 NOP2    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:35649 NPR1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:33290 NQM1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:32098 NRG1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:36403 OPI1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:36618 PFS1    BioGRID  PubMed Two-hybrid 
    BioGRID:35187 BioGRID:34089 PHD1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:35856 PPG1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:32491 PPM1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:35153 PPZ1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:33383 PRE9    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:36745 PRP22    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:35187 BioGRID:34349 PSH1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:33816 PTK2    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:31881 PTP1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:31306 RAD5    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:35137 RAD52    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:32270 RAD9    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:35250 RCO1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:31209 RET2    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:32191 RGP1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:36395 RIM101    BioGRID  PubMed Negative Genetic; Phenotypic Suppression 
    BioGRID:35187 BioGRID:32307 RKM4    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:34872 RPI1    BioGRID  PubMed Positive Genetic 
    BioGRID:35187 BioGRID:32035 RPN4    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:33200 RPT6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:35187 BioGRID:33883 RSF2    BioGRID  PubMed Positive Genetic 
    BioGRID:35187 BioGRID:32030 RTK1    BioGRID  PubMed Positive Genetic 
    BioGRID:35187 BioGRID:34476 RTS2    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:31249 RTT109    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:36753 SBH2    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:36552 SET1    BioGRID  PubMed Positive Genetic 
    BioGRID:35187 BioGRID:33591 SET2    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:35603 SIN4    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:32561 SMT3    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:35187 SOK2    BioGRID  PubMed Reconstituted Complex 
    BioGRID:35187 BioGRID:36751 SPC25    BioGRID  PubMed Two-hybrid 
    BioGRID:35187 BioGRID:36611 STB5    BioGRID  PubMed Positive Genetic 
    BioGRID:35187 BioGRID:36856 SWI4    BioGRID  PubMed Positive Genetic 
    BioGRID:35187 BioGRID:33753 SYS1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:33524 TAF1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:35187 BioGRID:33703 TDH1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:32787 TEC1    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:35187 BioGRID:33342 TEL2    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:33595 TPK1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:35981 TPK2    BioGRID  PubMed Dosage Rescue; Positive Genetic; Synthetic Growth Defect 
    BioGRID:35187 BioGRID:33971 TPK3    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:34729 TYE7    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:33802 UTR1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:31667 VIP1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:33348 VMA21    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35187 BioGRID:34152 VPS51    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:35128 VPS71    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:31788 VPS8    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:33616 YAK1    BioGRID  PubMed Positive Genetic; Synthetic Rescue 
    BioGRID:35187 BioGRID:32933 YBR238C    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:36867 YCK3    BioGRID  PubMed Positive Genetic 
    BioGRID:35187 BioGRID:34098 YKL033W-A    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:35142 YOX1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:31529 YPT6    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:35017 YVH1    BioGRID  PubMed Negative Genetic 
    BioGRID:35187 BioGRID:31399 ZRT2    BioGRID  PubMed Negative Genetic 
    • Meiosis - yeast, organism-specific biosystem (from KEGG)
      Meiosis - yeast, organism-specific biosystemDuring meiosis, a single round of DNA replication is followed by two rounds of chromosome segregation, called meiosis I and meiosis II. At meiosis I, one pair of sister chromatids recombines with, th...
    • Meiosis - yeast, conserved biosystem (from KEGG)
      Meiosis - yeast, conserved biosystemDuring meiosis, a single round of DNA replication is followed by two rounds of chromosome segregation, called meiosis I and meiosis II. At meiosis I, one pair of sister chromatids recombines with, th...

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    sequence-specific DNA binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    sequence-specific DNA binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    pseudohyphal growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    regulation of transcription, DNA-dependent IEA
    Inferred from Electronic Annotation
    more info
    		  
    transcription, DNA-dependent IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Names
    Sok2p
    NP_013729.1
    • Nuclear protein that negatively regulates pseudohyphal differentiation; plays a regulatory role in the cyclic AMP (cAMP)-dependent protein kinase (PKA) signal transduction pathway; SOK2 has a paralog, PHD1, that arose from the whole genome duplication

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3

      Range
      303236..305593, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182512.1 → NP_013729.1  Sok2p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P53438
      Conserved Domains (1) summary
      pfam04383
      Location:437 – 509
      Blast Score: 134
      KilA-N; KilA-N domain
    Nucleotide Protein
    Heading Accession and Version
    genomic BK006946.2 DAA09914.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53438.1 GenPept

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

      Table of contents

      Related information

      • BioProjects
        BioProjects related to a gene
      • BioSystems
        BioSystems
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • Full text in PMC
        PMC links
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • GEO Profiles
        Related GEO
      • HomoloGene
        Links between HomoloGene and Gene are provided by the HomoloGene group when a gene is included in a HomoloGene record.
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed (GeneRIF)
        GeneRIF -- Gene Reference Into Function Staff of the Index Section in the National Library of Medicine review the current literature. When they find articles focused on the structure and function of a gene, they write a brief summary of the impact of the paper and make the connection between the citation (PubMed) and Gene. An interface exists for interested users to submit such data as well. http://www.ncbi.nlm.nih.gov/projects/GeneRIF/GeneRIFhelp.html
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • Taxonomy
        Link to related taxonomy entry

      Links to other resources

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