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THS1 threonine--tRNA ligase THS1 [ Saccharomyces cerevisiae S288c ]

Gene ID: 854732, updated on 5-Oct-2014
Gene symbol
THS1
Gene description
threonine--tRNA ligase THS1
Primary source
SGD:S000001340
Locus tag
YIL078W
Gene type
protein coding
RNA name
threonine--tRNA ligase THS1
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See THS1 in MapViewer
Location:
chromosome: IX
Exon count:
1
Sequence:
Chromosome: IX; NC_001141.2 (212499..214703)

Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene tRNA Neighboring gene Air1p Neighboring gene hypothetical protein Neighboring gene Sec28p

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
aminoacyl-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
ligase activity IEA
Inferred from Electronic Annotation
more info
 
ligase activity, forming aminoacyl-tRNA and related compounds IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
threonine-tRNA ligase activity IDA
Inferred from Direct Assay
more info
PubMed 
threonine-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
threonine-tRNA ligase activity ISA
Inferred from Sequence Alignment
more info
PubMed 
Process Evidence Code Pubs
cytoplasmic translation IMP
Inferred from Mutant Phenotype
more info
PubMed 
tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 
tRNA aminoacylation for protein translation IEA
Inferred from Electronic Annotation
more info
 
threonyl-tRNA aminoacylation IDA
Inferred from Direct Assay
more info
PubMed 
threonyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 
threonyl-tRNA aminoacylation ISA
Inferred from Sequence Alignment
more info
PubMed 
translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
Names
threonine--tRNA ligase THS1
NP_116578.3
  • Threonyl-tRNA synthetase; essential cytoplasmic protein

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001141.2 

    Range
    212499..214703
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179428.3NP_116578.3  threonine--tRNA ligase THS1 [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_116578.3

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P04801
    Conserved Domains (5) summary
    cd01667
    Location:76140
    TGS_ThrRS_N; TGS _ThrRS_N: ThrRS (threonyl-tRNA Synthetase) is a class II tRNA synthetase that couples threonine to its cognate tRNA. In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and ...
    PLN02908
    Location:46728
    PLN02908; threonyl-tRNA synthetase
    cd00771
    Location:328627
    ThrRS_core; Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent ...
    cd00860
    Location:627721
    ThrRS_anticodon; ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is ...
    pfam07973
    Location:257305
    tRNA_SAD; Threonyl and Alanyl tRNA synthetase second additional domain