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    SIM1 Sim1p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 854683, updated on 21-Jan-2012
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    Summary

    Gene symbol
    SIM1
    Gene description
    Sim1p
    Primary source
    SGD:S000001385
    Locus tag
    YIL123W
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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    Genomic context

    Sequence :
    Chromosome: IX; NC_001141.2 (128151..129581)
    See SIM1 in MapViewer

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene Kgd1p Neighboring gene Ayr1p Neighboring gene Pog1p Neighboring gene Qdr2p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. The yeast Cbk1 kinase regulates mRNA localization via the mRNA-binding protein Ssd1. Kurischko C, et al. J Cell Biol, 2011 Feb 21. PMID 21339329.
    2. A genome-wide enhancer screen implicates sphingolipid composition in vacuolar ATPase function in Saccharomyces cerevisiae. Finnigan GC, et al. Genetics, 2011 Mar. PMID 21196517.
    3. The genetic landscape of a cell. Costanzo M, et al. Science, 2010 Jan 22. PMID 20093466.
    4. Integrating high-throughput genetic interaction mapping and high-content screening to explore yeast spindle morphogenesis. Vizeacoumar FJ, et al. J Cell Biol, 2010 Jan 11. PMID 20065090.
    5. Distinct roles for Khd1p in the localization and expression of bud-localized mRNAs in yeast. Hasegawa Y, et al. RNA, 2008 Nov. PMID 18805955.

    See all (14) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:34868 BioGRID:36693 ANP1    BioGRID  PubMed Negative Genetic 
    BioGRID:34868 BioGRID:32897 BEM1    BioGRID  PubMed Negative Genetic 
    BioGRID:34868 BioGRID:36749 BIM1    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:34868 BioGRID:35668 CBK1    BioGRID  PubMed Dosage Rescue 
    BioGRID:34868 BioGRID:32473 ERD1    BioGRID  PubMed Negative Genetic 
    BioGRID:34868 BioGRID:35410 FUS2    BioGRID  PubMed Negative Genetic 
    BioGRID:34868 BioGRID:32665 HEK2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:34868 BioGRID:33831 HOC1    BioGRID  PubMed Negative Genetic 
    BioGRID:34868 BioGRID:33933 HYM1    BioGRID  PubMed Dosage Rescue 
    BioGRID:34868 BioGRID:32548 ITR1    BioGRID  PubMed Positive Genetic 
    BioGRID:34868 BioGRID:33579 MNN11    BioGRID  PubMed Negative Genetic 
    BioGRID:34868 BioGRID:31111 MOB2    BioGRID  PubMed Dosage Rescue 
    BioGRID:34868 BioGRID:32098 NRG1    BioGRID  PubMed Positive Genetic 
    BioGRID:34868 BioGRID:36918 PAB1    BioGRID  PubMed Two-hybrid 
    BioGRID:34868 BioGRID:32871 SEC66    BioGRID  PubMed Negative Genetic 
    BioGRID:34868 BioGRID:34437 SHE4    BioGRID  PubMed Negative Genetic 
    BioGRID:34868 BioGRID:34738 SOG2    BioGRID  PubMed Dosage Rescue 
    BioGRID:34868 BioGRID:32345 SSD1    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:34868 BioGRID:34862 TAO3    BioGRID  PubMed Dosage Rescue 
    BioGRID:34868 BioGRID:31215 UBI4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:34868 BioGRID:34174 UTH1    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement 
    BioGRID:34868 BioGRID:33348 VMA21    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:34868 BioGRID:33349 VOA1    BioGRID  PubMed Synthetic Growth Defect 
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    General gene information

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    fungal-type cell wall organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    cell wall IEA
    Inferred from Electronic Annotation
    more info
    		  
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
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    General protein information

    Names
    Sim1p
    NP_012143.2
    • Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) that may participate in DNA replication, promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2

      Range
      128151..129581
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179471.2 → NP_012143.2  Sim1p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P40472
      Conserved Domains (1) summary
      pfam03856
      Location:220 – 463
      Blast Score: 1068
      SUN; Beta-glucosidase (SUN family)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006942.2 DAA08430.2
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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