RPS12 Rps12p [Saccharomyces cerevisiae S288c] - Gene

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Summary

Gene symbol: RPS12
Gene description: Rps12p
Primary source: SGD:S000005896
Locus tag: YOR369C
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Saccharomyces cerevisiae S288c (strain: S288c)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces

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Genomic context

Sequence :: Chromosome: XV; NC_001147.6 (1028194..1028625, complement)

See RPS12 in MapViewer

Chromosome XV - NC_001147.6 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

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Interactions

Products	Interactant	Other Gene	Source	Pubs	Description
BioGRID:34752	BioGRID:35876	BRE5	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34752	BioGRID:36110	BTS1	BioGRID	PubMed	Phenotypic Enhancement
BioGRID:34752	BioGRID:35002	DSN1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34752	BioGRID:35584	GIS2	BioGRID	PubMed	Affinity Capture-MS; Affinity Capture-RNA
BioGRID:34752	BioGRID:33726	KAR2	BioGRID	PubMed	Positive Genetic
BioGRID:34752	BioGRID:33129	NAB2	BioGRID	PubMed	Affinity Capture-RNA
BioGRID:34752	BioGRID:35993	NAB3	BioGRID	PubMed	Affinity Capture-RNA
BioGRID:34752	BioGRID:31191	PHO4	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34752	BioGRID:31217	PRP19	BioGRID	PubMed	Co-purification
BioGRID:34752	BioGRID:35629	RIO2	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34752	BioGRID:34547	RPB2	BioGRID	PubMed	Affinity Capture-RNA
BioGRID:34752	BioGRID:34967	RPB3	BioGRID	PubMed	Affinity Capture-RNA
BioGRID:34752	BioGRID:36458	RPN1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34752	BioGRID:31152	RPN11	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34752	BioGRID:31689	SEN1	BioGRID	PubMed	Affinity Capture-RNA
BioGRID:34752	BioGRID:34678	SNF2	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34752	BioGRID:31147	SPB4	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34752	BioGRID:36586	SPO12	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34752	BioGRID:33308	SPT4	BioGRID	PubMed	Phenotypic Suppression
BioGRID:34752	BioGRID:32977	SSH1	BioGRID	PubMed	Phenotypic Enhancement
BioGRID:34752	BioGRID:31215	UBI4	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34752	BioGRID:36901	UBP3	BioGRID	PubMed	Affinity Capture-MS

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General gene information

Homology

Homologs of the RPS12 gene: The RPS12 gene is conserved in human, chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, C.elegans, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana, and rice.

Pathways from BioSystems

Cap-dependent Translation Initiation, organism-specific biosystem (from REACTOME)
Cap-dependent Translation Initiation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Eukaryotic Translation Elongation, organism-specific biosystem (from REACTOME)
Eukaryotic Translation Elongation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Eukaryotic Translation Initiation, organism-specific biosystem (from REACTOME)
Eukaryotic Translation Initiation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Formation of a pool of free 40S subunits, organism-specific biosystem (from REACTOME)
Formation of a pool of free 40S subunits, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Formation of the ternary complex, and subsequently, the 43S complex, organism-specific biosystem (from REACTOME)
Formation of the ternary complex, and subsequently, the 43S complex, organism-specific biosystemcomputationally inferred pathway (not manually curated)
GTP hydrolysis and joining of the 60S ribosomal subunit, organism-specific biosystem (from REACTOME)
GTP hydrolysis and joining of the 60S ribosomal subunit, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Gene Expression, organism-specific biosystem (from REACTOME)
Gene Expression, organism-specific biosystemcomputationally inferred pathway (not manually curated)
L13a-mediated translational silencing of Ceruloplasmin expression, organism-specific biosystem (from REACTOME)
L13a-mediated translational silencing of Ceruloplasmin expression, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Metabolism of proteins, organism-specific biosystem (from REACTOME)
Metabolism of proteins, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Peptide chain elongation, organism-specific biosystem (from REACTOME)
Peptide chain elongation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Ribosomal scanning and start codon recognition, organism-specific biosystem (from REACTOME)
Ribosomal scanning and start codon recognition, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Ribosome, organism-specific biosystem (from KEGG)
Ribosome, organism-specific biosystem
Ribosome
Ribosome, conserved biosystem (from KEGG)
Ribosome, conserved biosystem
Ribosome
Ribosome, eukaryotes, organism-specific biosystem (from KEGG)
Ribosome, eukaryotes, organism-specific biosystemStructural complex; Genetic information processing; Ribosome
SRP-dependent cotranslational protein targeting to membrane, organism-specific biosystem (from REACTOME)
SRP-dependent cotranslational protein targeting to membrane, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Translation, organism-specific biosystem (from REACTOME)
Translation, organism-specific biosystemcomputationally inferred pathway (not manually curated)

Gene Ontology Provided by GO

Function	Evidence Code	Pubs
structural constituent of ribosome	IDA Inferred from Direct Assay more info	PubMed
structural constituent of ribosome	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
cytoplasmic translation	IC Inferred by Curator more info	PubMed
translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
cytoplasm	IEA Inferred from Electronic Annotation more info
cytosolic small ribosomal subunit	IDA Inferred from Direct Assay more info	PubMed
intracellular	IEA Inferred from Electronic Annotation more info
ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
ribosome	IEA Inferred from Electronic Annotation more info

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General protein information

Names: Rps12p

NP_015014.1

Protein component of the small (40S) ribosomal subunit; has similarity to rat ribosomal protein S12

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NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001147.6

Range

1028194..1028625, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001183789.1 → NP_015014.1 Rps12p [Saccharomyces cerevisiae S288c]

Status: PROVISIONAL

UniProtKB/Swiss-Prot

P48589

Conserved Domains (1) summary

cl00600
Location:26 – 114
Blast Score: 204

Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family