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    CIN1 Cin1p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 854531, updated on 8-Jan-2012
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    Summary

    Gene symbol
    CIN1
    Gene description
    Cin1p
    Primary source
    SGD:S000005876
    Locus tag
    YOR349W
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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    Genomic context

    Sequence :
    Chromosome: XV; NC_001147.6 (989789..992833)
    See CIN1 in MapViewer

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Pyk2p Neighboring gene Put4p Neighboring gene Mne1p Neighboring gene Mek1p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. Hoppins S, et al. J Cell Biol, 2011 Oct 17. PMID 21987634.
    2. Epistatic relationships reveal the functional organization of yeast transcription factors. Zheng J, et al. Mol Syst Biol, 2010 Oct 5. PMID 20959818.
    3. The genetic landscape of a cell. Costanzo M, et al. Science, 2010 Jan 22. PMID 20093466.
    4. Integrating high-throughput genetic interaction mapping and high-content screening to explore yeast spindle morphogenesis. Vizeacoumar FJ, et al. J Cell Biol, 2010 Jan 11. PMID 20065090.
    5. Purification of nuclear poly(A)-binding protein Nab2 reveals association with the yeast transcriptome and a messenger ribonucleoprotein core structure. Batisse J, et al. J Biol Chem, 2009 Dec 11. PMID 19840948.

    See all (37) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:34734 BioGRID:31301 AAT2    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:31107 ACT1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:32320 AKR1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:35680 ALF1    BioGRID  PubMed Dosage Lethality; Phenotypic Enhancement 
    BioGRID:34734 BioGRID:36562 ARP1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:34734 BioGRID:31358 ARP6    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34734 BioGRID:34535 ARP8    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:34456 ASE1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:31746 ATS1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:33807 BFA1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:30954 BIK1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34734 BioGRID:36749 BIM1    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34734 BioGRID:35876 BRE5    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:33440 BUB1    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:34734 BioGRID:35231 BUB2    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:34429 BUB3    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:34734 BioGRID:33066 CDC55    BioGRID  PubMed Affinity Capture-MS; Negative Genetic 
    BioGRID:34734 BioGRID:32304 CHL4    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:34734 BioGRID:35376 CIK1    BioGRID  PubMed Positive Genetic 
    BioGRID:34734 BioGRID:35922 CIN2    BioGRID  PubMed Dosage Lethality; Dosage Rescue; Synthetic Growth Defect 
    BioGRID:34734 BioGRID:35315 CIN4    BioGRID  PubMed Dosage Rescue; Synthetic Growth Defect; Synthetic Rescue 
    BioGRID:34734 BioGRID:36668 CIN8    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:34734 BioGRID:32835 CKS1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:31058 CSM1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:34734 BioGRID:35254 CTF18    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34734 BioGRID:36159 CTF19    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:34734 BioGRID:31640 CTF3    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:36302 CTF4    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:34734 BioGRID:36625 CTF8    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34734 BioGRID:34272 CTR9    BioGRID  PubMed Positive Genetic 
    BioGRID:34734 BioGRID:35014 DAL81    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:30968 DCC1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34734 BioGRID:33952 DOA1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:34185 DYN1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:34734 BioGRID:32483 DYN2    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:34734 BioGRID:35479 DYN3    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:34734 BioGRID:33978 ELF1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:34085 ELM1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:32569 EUG1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:31172 FAB1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:32723 GAL1    BioGRID  PubMed Positive Genetic 
    BioGRID:34734 BioGRID:35487 GAS1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:35635 GCR2    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:34600 GEP3    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:35676 GIM3    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:34734 BioGRID:36728 GIM4    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:34734 BioGRID:35049 GIM5    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34734 BioGRID:32665 HEK2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:34734 BioGRID:32711 HHT1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:34734 BioGRID:32227 HMO1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:35204 HOF1    BioGRID  PubMed Positive Genetic 
    BioGRID:34734 BioGRID:35364 HSC82    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:34734 BioGRID:35923 HSP82    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:34734 BioGRID:34392 HTZ1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:34734 BioGRID:31643 IKI3    BioGRID  PubMed Positive Genetic 
    BioGRID:34734 BioGRID:35976 IPL1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:34734 BioGRID:32712 IPP1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:36160 IRC15    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:34692 ISW2    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:33119 ITC1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:35474 JNM1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34734 BioGRID:35944 KAR9    BioGRID  PubMed Synthetic Lethality 
    BioGRID:34734 BioGRID:36028 KIP2    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:34734 BioGRID:32581 KRE28    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:31266 LDB18    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:35681 LSM7    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:33164 MAD1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34734 BioGRID:33729 MAD2    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34734 BioGRID:33742 MAD3    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:34734 BioGRID:34687 MBF1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:32374 MCM21    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:34734 BioGRID:32049 MED2    BioGRID  PubMed Positive Genetic 
    BioGRID:34734 BioGRID:34568 MED4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:34734 BioGRID:33900 MGM101    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:34993 MPH1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:35077 MSC1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:33129 NAB2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:34734 BioGRID:36009 NIP100    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:34734 BioGRID:36736 NUG1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:34734 BioGRID:32203 NUM1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34734 BioGRID:34213 NUP133    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:32245 NUP42    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:35765 OCA2    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:34734 BioGRID:36403 OPI1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:33320 PAC10    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:34734 BioGRID:32540 PAC11    BioGRID  PubMed Synthetic Lethality 
    BioGRID:34734 BioGRID:36737 PAC2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Dosage Rescue 
    BioGRID:34734 BioGRID:34106 PAN3    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:32694 PDR3    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:32170 PDS1    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:34734 BioGRID:33582 PFD1    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:34734 BioGRID:32794 POL30    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:35445 PPA2    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:36035 PPT2    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:36745 PRP22    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:36358 PZF1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:34654 RBL2    BioGRID  PubMed Dosage Lethality; Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34734 BioGRID:34761 RDR1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:32208 RPA14    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:36922 RPH1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:32035 RPN4    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:34404 RRP6    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:31195 RSC8    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:32996 RTF1    BioGRID  PubMed Positive Genetic 
    BioGRID:34734 BioGRID:34419 RTS1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:31249 RTT109    BioGRID  PubMed Synthetic Lethality 
    BioGRID:34734 BioGRID:32210 SAC3    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:33181 SGF73    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:32641 SHP1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:36861 SLX8    BioGRID  PubMed Positive Genetic 
    BioGRID:34734 BioGRID:33681 SMC3    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:36397 SNF6    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:32454 SPT3    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:30951 STE50    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:32663 STU1    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:34734 BioGRID:31320 STU2    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:31755 SWC3    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34734 BioGRID:32926 SWC5    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34734 BioGRID:31792 SWD1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:32391 SWR1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34734 BioGRID:35045 TAF13    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:32266 TCP1    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:34734 BioGRID:35699 TEP1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:34685 TIM18    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:35056 TUB1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:34734 BioGRID:31109 TUB2    BioGRID  PubMed Affinity Capture-Western; Synthetic Lethality 
    BioGRID:34734 BioGRID:35081 TUB3    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:34734 BioGRID:36901 UBP3    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:34586 ULS1    BioGRID  PubMed Positive Genetic 
    BioGRID:34734 BioGRID:31633 VID22    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:32103 VMS1    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:33882 VPS70    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:35128 VPS71    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34734 BioGRID:32537 VPS72    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34734 BioGRID:35717 YAF9    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:34734 BioGRID:31539 YCS4    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:36916 YER163C    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:33263 YGR021W    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:31469 YKE2    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:34734 BioGRID:31609 YLR346C    BioGRID  PubMed Negative Genetic 
    BioGRID:34734 BioGRID:36525 YNG2    BioGRID  PubMed Synthetic Lethality 
    BioGRID:34734 BioGRID:31529 YPT6    BioGRID  PubMed Negative Genetic; Positive Genetic 
    BioGRID:34734 BioGRID:33024 ZRT1    BioGRID  PubMed Negative Genetic 
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    General gene information

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    beta-tubulin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    protein folding IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    protein folding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
    		  
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    General protein information

    Names
    Cin1p
    NP_014994.1
    • Tubulin folding factor D involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6

      Range
      989789..992833
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183769.1 → NP_014994.1  Cin1p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P40987
      Conserved Domains (1) summary
      COG5234
      Location:1 – 1012
      Blast Score: 3218
      CIN1; Beta-tubulin folding cofactor D [Posttranslational modification, protein turnover, chaperones / Cytoskeleton]
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006948.2 DAA11110.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    P40987.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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