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STE4 Ste4p [ Saccharomyces cerevisiae S288c ]

Gene ID: 854387, updated on 7-Dec-2014
Gene symbol
STE4
Gene description
Ste4p
Primary source
SGD:S000005738
Locus tag
YOR212W
Gene type
protein coding
RNA name
Ste4p
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
HMD2
See STE4 in MapViewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (742910..744181)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene DNA-directed RNA polymerase core subunit RPB10 Neighboring gene dynamin-related GTPase MGM1 Neighboring gene Sas5p Neighboring gene Spr2p

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • MAPK Signaling Pathway, organism-specific biosystem (from WikiPathways)
    MAPK Signaling Pathway, organism-specific biosystemThe MAPK/ERK pathway is a signal transduction pathway that couples intracellular responses to the binding of growth factors to cell surface receptors. In many cell types, activation of this pathway p...
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
signal transducer activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
heterotrimeric G-protein complex IDA
Inferred from Direct Assay
more info
PubMed 
heterotrimeric G-protein complex IMP
Inferred from Mutant Phenotype
more info
PubMed 
mating projection IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
Names
Ste4p
NP_014855.3
  • G protein beta subunit; forms a dimer with Ste18p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste18p to dampen signaling; may recruit Rho1p to the polarized growth site during mating; contains WD40 repeats

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 

    Range
    742910..744181
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183631.3NP_014855.3  Ste4p [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_014855.3

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P18851
    Conserved Domains (2) summary
    COG2319
    Location:91420
    COG2319; FOG: WD40 repeat [General function prediction only]
    cd00200
    Location:87419
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...