Format

Send to:

Choose Destination

Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 85430, updated on 26-May-2016
Official Symbol
Herpud1provided by RGD
Official Full Name
homocysteine inducible ER protein with ubiquitin like domain 1provided by RGD
Primary source
RGD:620818
See related
Ensembl:ENSRNOG00000018796
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
Sup
Summary
human homolog is a membrane protein that is induced by stress and may be involved in the cellular survival response to stress [RGD, Feb 2006]
Orthologs
Location:
19p12
Exon count:
8
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (11046903..11057570, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 19 NC_005118.3 (11027622..11038305, complement)

Chromosome 19 - NC_005118.4Genomic Context describing neighboring genes Neighboring gene NLR family, CARD domain containing 5 Neighboring gene protein NLRC5-like Neighboring gene uncharacterized LOC102553339 Neighboring gene solute carrier family 12 member 3-like

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
ion channel binding IPI
Inferred from Physical Interaction
more info
PubMed 
ion channel binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cellular calcium ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
endoplasmic reticulum calcium ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
endoplasmic reticulum calcium ion homeostasis ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum unfolded protein response IMP
Inferred from Mutant Phenotype
more info
PubMed 
endoplasmic reticulum unfolded protein response ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
negative regulation of intrinsic apoptotic signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of intrinsic apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
positive regulation of ER-associated ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of ER-associated ubiquitin-dependent protein catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
positive regulation of protein binding IEA
Inferred from Electronic Annotation
more info
 
positive regulation of protein binding ISO
Inferred from Sequence Orthology
more info
 
regulation of ER-associated ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
regulation of protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
regulation of protein ubiquitination ISO
Inferred from Sequence Orthology
more info
 
response to endoplasmic reticulum stress IGI
Inferred from Genetic Interaction
more info
PubMed 
response to unfolded protein ISO
Inferred from Sequence Orthology
more info
 
retrograde protein transport, ER to cytosol IEA
Inferred from Electronic Annotation
more info
 
retrograde protein transport, ER to cytosol ISO
Inferred from Sequence Orthology
more info
 
ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
Lewy body core IEA
Inferred from Electronic Annotation
more info
 
Lewy body core ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with calcium channel complex IPI
Inferred from Physical Interaction
more info
PubMed 
colocalizes_with calcium channel complex ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum membrane TAS
Traceable Author Statement
more info
PubMed 
integral component of membrane ISO
Inferred from Sequence Orthology
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
Names
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053523.1NP_445975.1  homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

    See identical proteins and their annotated locations for NP_445975.1

    Status: PROVISIONAL

    Source sequence(s)
    AB033771
    UniProtKB/TrEMBL
    Q9ESS9
    Related
    ENSRNOP00000025559, ENSRNOT00000025559
    Conserved Domains (2) summary
    cd01790
    Location:987
    Herp_N; Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain protein
    smart00213
    Location:1086
    UBQ; Ubiquitin homologues

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005118.4 Reference Rnor_6.0 Primary Assembly

    Range
    11046903..11057570 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006255133.2XP_006255195.1  

    Conserved Domains (2) summary
    cd01790
    Location:107184
    Herp_N; Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain protein
    smart00213
    Location:108183
    UBQ; Ubiquitin homologues

Alternate Rn_Celera

Genomic

  1. AC_000087.1 Alternate Rn_Celera

    Range
    10486005..10496352 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)