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    INP54 Inp54p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 854089, updated on 21-May-2012
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    Summary

    Gene symbol
    INP54
    Gene description
    Inp54p
    Primary source
    SGD:S000005426
    Locus tag
    YOL065C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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    Genomic context

    Location :
    chromosome: XV
    Sequence :
    Chromosome: XV; NC_001147.6 (204731..205885, complement)
    See INP54 in MapViewer

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Rtg1p Neighboring gene Rib2p Neighboring gene Met22p Neighboring gene Crt10p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. La-motif-dependent mRNA association with Slf1 promotes copper detoxification in yeast. Schenk L, et al. RNA, 2012 Mar. PMID 22271760.
    2. A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. Hoppins S, et al. J Cell Biol, 2011 Oct 17. PMID 21987634.
    3. An integrated approach to characterize genetic interaction networks in yeast metabolism. Szappanos B, et al. Nat Genet, 2011 May 29. PMID 21623372.
    4. A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking. Aguilar PS, et al. Nat Struct Mol Biol, 2010 Jul. PMID 20526336.
    5. The genetic landscape of a cell. Costanzo M, et al. Science, 2010 Jan 22. PMID 20093466.

    See all (20) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:34336 BioGRID:33023 ADH4    BioGRID  PubMed Negative Genetic 
    BioGRID:34336 BioGRID:34125 CAP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:34336 BioGRID:32832 CCZ1    BioGRID  PubMed Positive Genetic 
    BioGRID:34336 BioGRID:36011 COX10    BioGRID  PubMed Negative Genetic 
    BioGRID:34336 BioGRID:32737 CSG2    BioGRID  PubMed Negative Genetic 
    BioGRID:34336 BioGRID:33952 DOA1    BioGRID  PubMed Negative Genetic 
    BioGRID:34336 BioGRID:33305 ERG25    BioGRID  PubMed Negative Genetic 
    BioGRID:34336 BioGRID:33508 GND2    BioGRID  PubMed Negative Genetic 
    BioGRID:34336 BioGRID:35029 GTT1    BioGRID  PubMed Negative Genetic 
    BioGRID:34336 BioGRID:35473 HER2    BioGRID  PubMed Negative Genetic 
    BioGRID:34336 BioGRID:35204 HOF1    BioGRID  PubMed Positive Genetic 
    BioGRID:34336 BioGRID:35923 HSP82    BioGRID  PubMed Synthetic Growth Defect; Two-hybrid 
    BioGRID:34336 BioGRID:36528 HXT1    BioGRID  PubMed Positive Genetic 
    BioGRID:34336 BioGRID:34302 IZH4    BioGRID  PubMed Negative Genetic 
    BioGRID:34336 BioGRID:33080 KEM1    BioGRID  PubMed Positive Genetic 
    BioGRID:34336 BioGRID:34615 MCT1    BioGRID  PubMed Negative Genetic 
    BioGRID:34336 BioGRID:34715 MIP1    BioGRID  PubMed Negative Genetic 
    BioGRID:34336 BioGRID:34843 MLP2    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:34336 BioGRID:33914 MPH3    BioGRID  PubMed Positive Genetic 
    BioGRID:34336 BioGRID:32531 PEX29    BioGRID  PubMed Two-hybrid 
    BioGRID:34336 BioGRID:34240 PFK27    BioGRID  PubMed Negative Genetic 
    BioGRID:34336 BioGRID:35080 PGA3    BioGRID  PubMed Negative Genetic 
    BioGRID:34336 BioGRID:36147 PHO85    BioGRID  PubMed Dosage Lethality 
    BioGRID:34336 BioGRID:31831 PRR2    BioGRID  PubMed Biochemical Activity 
    BioGRID:34336 BioGRID:34733 PUT4    BioGRID  PubMed Positive Genetic 
    BioGRID:34336 BioGRID:35725 RAS2    BioGRID  PubMed Positive Genetic 
    BioGRID:34336 BioGRID:33953 SAC1    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:34336 BioGRID:31897 SFA1    BioGRID  PubMed Positive Genetic 
    BioGRID:34336 BioGRID:34369 SIL1    BioGRID  PubMed Negative Genetic 
    BioGRID:34336 BioGRID:34400 SIN3    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:34336 BioGRID:36152 SKS1    BioGRID  PubMed Biochemical Activity 
    BioGRID:34336 BioGRID:36461 SLT2    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:34336 BioGRID:30946 SRO9    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:34336 BioGRID:33823 TOR1    BioGRID  PubMed Positive Genetic 
    BioGRID:34336 BioGRID:32129 TPS2    BioGRID  PubMed Negative Genetic 
    BioGRID:34336 BioGRID:31215 UBI4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:34336 BioGRID:33626 URA2    BioGRID  PubMed Negative Genetic 
    BioGRID:34336 BioGRID:36717 VAC8    BioGRID  PubMed Negative Genetic 
    BioGRID:34336 BioGRID:35928 VMA11    BioGRID  PubMed Positive Genetic 
    BioGRID:34336 BioGRID:34016 VPH2    BioGRID  PubMed Positive Genetic 
    BioGRID:34336 BioGRID:34294 YOL107W    BioGRID  PubMed Negative Genetic 
    BioGRID:34336 BioGRID:35264 YTA12    BioGRID  PubMed Negative Genetic 
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    General gene information

    Homology

    Pathways from BioSystems

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    phosphatidylinositol dephosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Names
    Inp54p
    NP_014576.1
    • Phosphatidylinositol 4,5-bisphosphate 5-phosphatase with a role in secretion, localizes to the endoplasmic reticulum via the C-terminal tail; lacks the Sac1 domain and proline-rich region found in the other 3 INP proteins
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6

      Range
      204731..205885, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183320.1 → NP_014576.1  Inp54p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q08227
      Conserved Domains (1) summary
      cd09074
      Location:6 – 322
      Blast Score: 697
      INPP5c; Catalytic domain of inositol polyphosphate 5-phosphatases
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006948.2 DAA10718.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08227.1 GenPept
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    Additional Links

    Gene LinkOut

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