RPL14A Rpl14ap [ Saccharomyces cerevisiae S288c ]

Gene ID: 853864, updated on 8-Jan-2012

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Summary

Gene symbol: RPL14A
Gene description: Rpl14ap
Primary source: SGD:S000001489
Locus tag: YKL006W
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Saccharomyces cerevisiae S288c (strain: S288c)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces

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Genomic context

Sequence :: Chromosome: XI; NC_001143.9 (431906..432720)

See RPL14A in MapViewer

Chromosome XI - NC_001143.9 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

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Interactions

Products	Interactant	Other Gene	Source	Pubs	Description
BioGRID:34127	BioGRID:32931	ABD1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:32683	ACH1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:31107	ACT1	BioGRID	PubMed	Synthetic Haploinsufficiency; Synthetic Rescue
BioGRID:34127	BioGRID:36750	AFG3	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:31055	AHC2	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:36207	APL4	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:33815	APS2	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36771	ARB1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:32864	ARL1	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:36562	ARP1	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:33675	ARP4	BioGRID	PubMed	Synthetic Lethality
BioGRID:34127	BioGRID:36357	ATG13	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:31560	ATP14	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:32897	BEM1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36905	BEM2	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36930	BMH1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:35876	BRE5	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:33386	CBF2	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:34850	CCT2	BioGRID	PubMed	Synthetic Rescue
BioGRID:34127	BioGRID:31825	CDC13	BioGRID	PubMed	Synthetic Rescue
BioGRID:34127	BioGRID:33135	CDC20	BioGRID	PubMed	Synthetic Growth Defect
BioGRID:34127	BioGRID:31579	CDC3	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:32219	CDC37	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:31066	CDC50	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:31594	CHS5	BioGRID	PubMed	Synthetic Growth Defect; Synthetic Lethality
BioGRID:34127	BioGRID:36484	CIC1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:32072	CIS1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:34441	CKB2	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:31478	CLB4	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:33419	CLC1	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:36907	COG3	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:35773	COG5	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36549	COX23	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:35254	CTF18	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:34432	DFG16	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:34699	DGK1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:35002	DSN1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:36392	ECM29	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:32778	ECM8	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:32564	EMI1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36084	ERI1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:33193	ERV14	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:32729	ETR1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:33503	GCN5	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:35584	GIS2	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:36877	GLC7	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:36622	GPI16	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:34313	HAL9	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:32677	HAP3	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:35909	HFI1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:35881	HOL1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36499	HTD2	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:33086	HUR1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:31211	HXK1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:35180	HXT2	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:34902	ICE2	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:35621	IES2	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:32543	IZH1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:34565	LCB4	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:33495	LSC2	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:33632	LSM1	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:35819	LST8	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:31742	LTE1	BioGRID	PubMed	Synthetic Lethality
BioGRID:34127	BioGRID:31458	MDL1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:31756	MDM10	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:34944	MET30	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36836	MET6	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:34226	MLP1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:34123	MRT4	BioGRID	PubMed	Affinity Capture-Western
BioGRID:34127	BioGRID:33129	NAB2	BioGRID	PubMed	Affinity Capture-RNA
BioGRID:34127	BioGRID:35703	NAF1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:32213	NBP2	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:35715	NOP15	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:32054	NTH1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:32245	NUP42	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:31852	NUS1	BioGRID	PubMed	Synthetic Rescue
BioGRID:34127	BioGRID:35101	ORC1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:32589	PAU10	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:35575	PDR17	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:35726	PHO23	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:32329	PMP3	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:33087	PMR1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:32662	POL12	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:33794	POL32	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:32953	POP4	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:32019	PRM7	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:32294	PRP28	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36350	PRP4	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:31784	PTA1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:32048	PTC1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36623	PTH1	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:31357	RAX2	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:35329	RIM13	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:33203	RIM8	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:35238	RIM9	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36631	RIX1	BioGRID	PubMed	Affinity Capture-Western
BioGRID:34127	BioGRID:32208	RPA14	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36577	RPC10	BioGRID	PubMed	Synthetic Rescue
BioGRID:34127	BioGRID:34212	RPF2	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:36389	RPL8A	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:36634	RPN10	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:32035	RPN4	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:33879	RPS5	BioGRID	PubMed	Synthetic Rescue
BioGRID:34127	BioGRID:33125	SCS3	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:33496	SDA1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:31476	SEC13	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:31536	SEC22	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36353	SEC23	BioGRID	PubMed	Synthetic Rescue
BioGRID:34127	BioGRID:34916	SEC28	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36368	SGE1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36133	SGF11	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:33181	SGF73	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:34992	SGN1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:31885	SHS1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:32385	SKP1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:36461	SLT2	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:31016	SNT1	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:31866	SOR2	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:35241	SOV1	BioGRID	PubMed	Synthetic Growth Defect
BioGRID:34127	BioGRID:31147	SPB4	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:31683	SPP382	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:30937	SPS22	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:34269	SPT20	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:32345	SSD1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36498	SSF1	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:35855	SSK2	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36987	SUS1	BioGRID	PubMed	Affinity Capture-MS; Negative Genetic
BioGRID:34127	BioGRID:31519	SYM1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:32199	TAF12	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:32895	TAF5	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:33139	TAF6	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:35090	TAF8	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:35414	TAF9	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:31789	TFC3	BioGRID	PubMed	Dosage Rescue
BioGRID:34127	BioGRID:31950	TRM3	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:31215	UBI4	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:36901	UBP3	BioGRID	PubMed	Affinity Capture-MS
BioGRID:34127	BioGRID:31160	UBP6	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:35401	UBP8	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:33436	UBR1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:31645	VAC14	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36678	VMA8	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:35831	VPS27	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36439	VPS29	BioGRID	PubMed	Positive Genetic
BioGRID:34127	BioGRID:34444	WHI2	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:34481	WHI5	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36672	YEL057C	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:31562	YHC1	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:33687	YJL068C	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:33876	YJR120W	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:31421	YLR152C	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:35815	YNL010W	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:34637	YOR246C	BioGRID	PubMed	Negative Genetic
BioGRID:34127	BioGRID:36766	YPT31	BioGRID	PubMed	Negative Genetic

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General gene information

Pathways from BioSystems

Cap-dependent Translation Initiation, organism-specific biosystem (from REACTOME)
Cap-dependent Translation Initiation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Eukaryotic Translation Elongation, organism-specific biosystem (from REACTOME)
Eukaryotic Translation Elongation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Eukaryotic Translation Initiation, organism-specific biosystem (from REACTOME)
Eukaryotic Translation Initiation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Formation of a pool of free 40S subunits, organism-specific biosystem (from REACTOME)
Formation of a pool of free 40S subunits, organism-specific biosystemcomputationally inferred pathway (not manually curated)
GTP hydrolysis and joining of the 60S ribosomal subunit, organism-specific biosystem (from REACTOME)
GTP hydrolysis and joining of the 60S ribosomal subunit, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Gene Expression, organism-specific biosystem (from REACTOME)
Gene Expression, organism-specific biosystemcomputationally inferred pathway (not manually curated)
L13a-mediated translational silencing of Ceruloplasmin expression, organism-specific biosystem (from REACTOME)
L13a-mediated translational silencing of Ceruloplasmin expression, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Metabolism of proteins, organism-specific biosystem (from REACTOME)
Metabolism of proteins, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Peptide chain elongation, organism-specific biosystem (from REACTOME)
Peptide chain elongation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Ribosome, organism-specific biosystem (from KEGG)
Ribosome, organism-specific biosystem
Ribosome
Ribosome, conserved biosystem (from KEGG)
Ribosome, conserved biosystem
Ribosome
Ribosome, eukaryotes, organism-specific biosystem (from KEGG)
Ribosome, eukaryotes, organism-specific biosystemStructural complex; Genetic information processing; Ribosome
SRP-dependent cotranslational protein targeting to membrane, organism-specific biosystem (from REACTOME)
SRP-dependent cotranslational protein targeting to membrane, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Translation, organism-specific biosystem (from REACTOME)
Translation, organism-specific biosystemcomputationally inferred pathway (not manually curated)

Gene Ontology Provided by GO

Function	Evidence Code	Pubs
RNA binding	IDA Inferred from Direct Assay more info	PubMed
structural constituent of ribosome	IEA Inferred from Electronic Annotation more info
structural constituent of ribosome	TAS Traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
cytoplasmic translation	TAS Traceable Author Statement more info	PubMed
translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
cytoplasm	IEA Inferred from Electronic Annotation more info
cytosolic large ribosomal subunit	TAS Traceable Author Statement more info	PubMed
intracellular	IEA Inferred from Electronic Annotation more info
ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
ribosome	IEA Inferred from Electronic Annotation more info

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General protein information

Names: Rpl14ap

NP_012920.1

N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl14Bp and has similarity to rat L14 ribosomal protein; rpl14a csh5 double null mutant exhibits synthetic slow growth

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NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001143.9

Range

431906..432720

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001179572.1 → NP_012920.1 Rpl14ap [Saccharomyces cerevisiae S288c]

Status: PROVISIONAL

UniProtKB/Swiss-Prot

P36105

Conserved Domains (2) summary

PTZ00065
Location:13 – 136
Blast Score: 215

PTZ00065; 60S ribosomal protein L14; Provisional

pfam01929
Location:55 – 127
Blast Score: 164

Ribosomal_L14e; Ribosomal protein L14