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    IXR1 Ixr1p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 853836, updated on 8-Jan-2012
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    Summary

    Gene symbol
    IXR1
    Gene description
    Ixr1p
    Primary source
    SGD:S000001515
    Locus tag
    YKL032C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    ORD1
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    Genomic context

    Sequence :
    Chromosome: XI; NC_001143.9 (380065..381858, complement)
    See IXR1 in MapViewer

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene Tti1p Neighboring gene tRNA Neighboring gene Mae1p Neighboring gene Tfa1p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Ixr1 is required for the expression of the ribonucleotide reductase Rnr1 and maintenance of dNTP pools. Tsaponina O, et al. PLoS Genet, 2011 May. PMID 21573136.
    2. Absence of mitochondrial translation control proteins extends life span by activating sirtuin-dependent silencing. Caballero A, et al. Mol Cell, 2011 May 6. PMID 21549315.
    3. Rewiring of genetic networks in response to DNA damage. Bandyopadhyay S, et al. Science, 2010 Dec 3. PMID 21127252.
    4. Epistatic relationships reveal the functional organization of yeast transcription factors. Zheng J, et al. Mol Syst Biol, 2010 Oct 5. PMID 20959818.
    5. Identification of response-modulated genetic interactions by sensitivity-based epistatic analysis. Batenchuk C, et al. BMC Genomics, 2010 Sep 10. PMID 20831804.

    See all (28) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. the combined activity of the Hmo 1 and the Ixr1 proteins provides efficient correction of both repair and replication errors.
      Title: [IXR1 and HMO1 genes jointly control the level of spontaneous mutagenesis in yeast Saccharomyces cerevisiae].
    2. Ixr1p is necessary for the high expression of HEM13 under hypoxic conditions and its function is exerted in vivo through the HEM13 promoter region extending from -577 to -419.
      Title: Ixr1p regulates oxygen-dependent HEM13 transcription.
    3. Data show that transcriptional adaptation from aerobiosis to hypoxia depends on ROX1 and IXR1 cross-regulation.
      Title: Regulatory factors controlling transcription of Saccharomyces cerevisiae IXR1 by oxygen levels: a model of transcriptional adaptation from aerobiosis to hypoxia implicating ROX1 and IXR1 cross-regulation.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:34101 BioGRID:31107 ACT1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32503 ADA2    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:34101 BioGRID:33177 AFT1    BioGRID  PubMed Negative Genetic; Positive Genetic 
    BioGRID:34101 BioGRID:35617 ALG9    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36693 ANP1    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:36440 ARD1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35059 ATP18    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35580 ATX1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:34509 AZF1    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:34230 BAS1    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:32897 BEM1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32965 BIT2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35605 BNI4    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34101 BioGRID:31987 BRE1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31289 BRE2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:34128 BYE1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36547 BZZ1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33427 CBP4    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35210 CCS1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33814 CDC8    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:34101 BioGRID:36803 CEM1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36917 CHD1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31594 CHS5    BioGRID  PubMed Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34101 BioGRID:34955 CKA1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35540 CLA4    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34101 BioGRID:31908 CLB3    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35835 CSE2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36001 CTI6    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:33750 CTK2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35092 CTK3    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36292 CTR1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:34439 CYC2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35525 DAL82    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32106 DBF4    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31753 DEP1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32898 DER1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:34432 DFG16    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35710 DMA2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33952 DOA1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36833 DOT6    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31443 DPH5    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31961 DUN1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34101 BioGRID:35690 EAF7    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35354 ECM5    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33453 ELP2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31564 EXG1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35755 FKH2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31604 FKS1    BioGRID  PubMed Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:34101 BioGRID:31223 FRA1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32682 FUS3    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:31125 GAT1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35313 GAT2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36723 GCN4    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:34101 BioGRID:33503 GCN5    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35635 GCR2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36828 GET2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36728 GIM4    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement 
    BioGRID:34101 BioGRID:35049 GIM5    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32151 GIS1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36776 GLN3    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36622 GPI16    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32023 GPR1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33646 GZF3    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36186 HAA1    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:32677 HAP3    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31041 HCM1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35805 HDA1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32665 HEK2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:34101 BioGRID:32710 HHF1    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:32691 HIR1    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:32227 HMO1    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:34101 BioGRID:34434 HMS1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32460 HPT1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:34032 HSL1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35180 HXT2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31327 IES3    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36621 IKI1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31643 IKI3    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32179 INO2    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:33726 KAR2    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:35944 KAR9    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:34101 BioGRID:32067 KCS1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36038 KES1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32009 KNH1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:34101 BioGRID:33287 KSS1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31528 LCB5    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:36125 LGE1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32990 MAL33    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:35532 MCK1    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:36242 MED1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:34863 MET18    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33212 MIG1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35016 MND2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36811 MOT2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35245 MOT3    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35077 MSC1    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:34284 MSN1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:34071 MSN4    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35194 MSS1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33129 NAB2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:34101 BioGRID:32052 NHP10    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36227 NHP6A    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33331 NNF2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35649 NPR1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35040 NUP188    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35724 OCA1    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:35765 OCA2    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:32122 OCA6    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:32369 OMS1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36403 OPI1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32764 ORC2    BioGRID  PubMed Synthetic Lethality 
    BioGRID:34101 BioGRID:33320 PAC10    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement 
    BioGRID:34101 BioGRID:34285 PAP2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32589 PAU10    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33430 PBP1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33233 PDR1    BioGRID  PubMed Positive Genetic; Synthetic Growth Defect 
    BioGRID:34101 BioGRID:34421 PET127    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35198 PEX12    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33381 PEX4    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35080 PGA3    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:31875 PHO13    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35726 PHO23    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement 
    BioGRID:34101 BioGRID:34403 PHO80    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:34655 PNT1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35856 PPG1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32130 PPH3    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35153 PPZ1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33555 PRP21    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31881 PTP1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:34603 PTP2    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:35379 RAD14    BioGRID  PubMed Synthetic Rescue 
    BioGRID:34101 BioGRID:33510 RAD2    BioGRID  PubMed Synthetic Rescue 
    BioGRID:34101 BioGRID:36915 RAD4    BioGRID  PubMed Synthetic Rescue 
    BioGRID:34101 BioGRID:36030 RAD53    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:34101 BioGRID:32270 RAD9    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:34101 BioGRID:35620 RAP1    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:35250 RCO1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31447 RFX1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31009 RHB1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36395 RIM101    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35329 RIM13    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:34664 RIM20    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33203 RIM8    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35238 RIM9    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32053 RMD1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36813 RNR1    BioGRID  PubMed Dosage Rescue 
    BioGRID:34101 BioGRID:34926 RNR3    BioGRID  PubMed Dosage Rescue 
    BioGRID:34101 BioGRID:34872 RPI1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32035 RPN4    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:34101 BioGRID:36469 RRF1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:34404 RRP6    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33301 RSC1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32996 RTF1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32600 RTG3    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33408 RTS3    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32801 RXT2    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement 
    BioGRID:34101 BioGRID:32210 SAC3    BioGRID  PubMed Phenotypic Suppression; Positive Genetic 
    BioGRID:34101 BioGRID:36873 SAK1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36784 SAP1    BioGRID  PubMed Two-hybrid 
    BioGRID:34101 BioGRID:35441 SAP30    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:30987 SAT4    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32727 SCO2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32522 SDC1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31536 SEC22    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36552 SET1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33591 SET2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36133 SGF11    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33181 SGF73    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:34400 SIN3    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35603 SIN4    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:36640 SKN7    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36461 SLT2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32144 SLU7    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35109 SML1    BioGRID  PubMed Synthetic Rescue 
    BioGRID:34101 BioGRID:32561 SMT3    BioGRID  PubMed Affinity Capture-MS; Two-hybrid 
    BioGRID:34101 BioGRID:35737 SNN1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33124 SOH1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35187 SOK2    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:35241 SOV1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:34101 BioGRID:36586 SPO12    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36044 SPP1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35357 SPT21    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32454 SPT3    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31330 SPT8    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36473 SRB2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35855 SSK2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31278 SSL1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32498 SSN2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35530 STB1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36433 STP2    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35230 STV1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31792 SWD1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33585 SWI3    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:31453 SWI6    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:34101 BioGRID:32391 SWR1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32895 TAF5    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33139 TAF6    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36601 THP2    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:36901 UBP3    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement 
    BioGRID:34101 BioGRID:36043 UME1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32257 UME6    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:34971 VID28    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32103 VMS1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35831 VPS27    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36114 VPS28    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35128 VPS71    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35065 WAR1    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:34891 XBP1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35717 YAF9    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:35010 YAP5    BioGRID  PubMed Positive Genetic 
    BioGRID:34101 BioGRID:32933 YBR238C    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:36568 YCK1    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:32180 YDR124W    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31213 YFR057W    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:33516 YGR266W    BioGRID  PubMed Negative Genetic 
    BioGRID:34101 BioGRID:31421 YLR152C    BioGRID  PubMed Negative Genetic 
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    General gene information

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    damaged DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    DNA repair IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    cellular response to hypoxia IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    cellular response to hypoxia IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    negative regulation of transcription from RNA polymerase II promoter IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    regulation of transcription, DNA-dependent IEA
    Inferred from Electronic Annotation
    more info
    		  
    transcription, DNA-dependent IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    colocalizes_with nuclear chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Names
    Ixr1p
    NP_012893.1
    • Protein that binds DNA containing intrastrand cross-links formed by cisplatin, contains two HMG (high mobility group box) domains, which confer the ability to bend cisplatin-modified DNA; mediates aerobic transcriptional repression of COX5b
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9

      Range
      380065..381858, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179598.1 → NP_012893.1  Ixr1p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P33417
      Conserved Domains (1) summary
      cd01390
      Location:361 – 423
      Blast Score: 173
      HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006944.2 DAA09124.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    P33417.2 GenPept
    Help top of page

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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