FAM40A family with sequence similarity 40, member A [Homo sapiens] - Gene

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Summary

Official Symbol: FAM40Aprovided by HGNC
Official Full Name: family with sequence similarity 40, member Aprovided by HGNC
Primary source: HGNC:25916
See related: Ensembl:ENSG00000143093; Vega:OTTHUMG00000170607
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: RP4-773N10.1; FLJ14743; KIAA1761; MGC148091

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Genomic context

Location :: 1p13.3

Sequence :: Chromosome: 1; NC_000001.10 (110577241..110597263)

See FAM40A in Epigenomics, MapViewer

Chromosome 1 - NC_000001.10 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

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Phenotypes

Review eQTL and phenotype association data in this region using PheGenI

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Products	Interactant	Other Gene	Source	Pubs	Description
BioGRID:124497	BioGRID:123842	CTTNBP2	BioGRID	PubMed	Affinity Capture-MS
BioGRID:124497	BioGRID:121000	CTTNBP2NL	BioGRID	PubMed	Affinity Capture-MS; Affinity Capture-Western
BioGRID:124497	BioGRID:207994	Dynll1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:124497	BioGRID:121534	FAM40B	BioGRID	PubMed	Affinity Capture-MS
BioGRID:124497	BioGRID:117566	FGFR1OP2	BioGRID	PubMed	Affinity Capture-MS
BioGRID:124497	BioGRID:110333	MCC	BioGRID	PubMed	Affinity Capture-MS
BioGRID:124497	BioGRID:117369	MOB4	BioGRID	PubMed	Affinity Capture-MS
BioGRID:124497	BioGRID:119722	MST4	BioGRID	PubMed	Affinity Capture-MS; Affinity Capture-Western
BioGRID:124497	BioGRID:116400	PDCD10	BioGRID	PubMed	Affinity Capture-MS
BioGRID:124497	BioGRID:111507	PPP2CA	BioGRID	PubMed	Affinity Capture-MS
BioGRID:124497	BioGRID:111508	PPP2CB	BioGRID	PubMed	Affinity Capture-MS
BioGRID:124497	BioGRID:111510	PPP2R1A	BioGRID	PubMed	Affinity Capture-MS; Affinity Capture-Western
BioGRID:124497	BioGRID:123136	SIKE1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:124497	BioGRID:113620	SLMAP	BioGRID	PubMed	Affinity Capture-MS
BioGRID:124497	BioGRID:114011	STK24	BioGRID	PubMed	Affinity Capture-MS
BioGRID:124497	BioGRID:115757	STK25	BioGRID	PubMed	Affinity Capture-MS
BioGRID:124497	BioGRID:112674	STRN	BioGRID	PubMed	Affinity Capture-MS; Affinity Capture-Western
BioGRID:124497	BioGRID:118999	STRN3	BioGRID	PubMed	Affinity Capture-MS
BioGRID:124497	BioGRID:118941	STRN4	BioGRID	PubMed	Affinity Capture-MS
BioGRID:124497	BioGRID:123249	TRAF3IP3	BioGRID	PubMed	Affinity Capture-MS; Affinity Capture-Western
BioGRID:124497	BioGRID:113164	UBC	BioGRID	PubMed	Affinity Capture-MS
BioGRID:124497	BioGRID:120139	ZRANB1	BioGRID	PubMed	Affinity Capture-MS

Function	Evidence Code	Pubs
molecular_function	ND No biological Data available more info
protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
cortical actin cytoskeleton organization	IMP Inferred from Mutant Phenotype more info
regulation of cell morphogenesis	IMP Inferred from Mutant Phenotype more info

Component	Evidence Code	Pubs
cytoplasm	IEA Inferred from Electronic Annotation more info
nucleus	IDA Inferred from Direct Assay more info	PubMed

General protein information

Preferred Names: protein FAM40A

Names: protein FAM40A; 6330569M22Rik; homolog of yeast FAR11 protein 1

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NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_033088.2 → NP_149079.2 protein FAM40A

Status: VALIDATED

Source sequence(s)

AB051548, BC067239, CB960147

Consensus CDS

CCDS30798.1

UniProtKB/Swiss-Prot

Q5VSL9

Related

ENSP00000358810, OTTHUMP00000013366, ENST00000369795, OTTHUMT00000032213

Conserved Domains (2) summary

pfam11882
Location:418 – 817
Blast Score: 1188

DUF3402; Domain of unknown function (DUF3402)

pfam07923
Location:66 – 350
Blast Score: 748

N1221; N1221-like protein

RefSeqs of Annotated Genomes: Build 37.3

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh37.p5 Primary Assembly

Genomic

NC_000001.10 Reference GRCh37.p5 Primary Assembly

Range

110577241..110597263

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

AC_000133.1 Alternate HuRef

Range

108446705..108466730

Download

GenBank, FASTA, Sequence Viewer (Graphics)

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Related Sequences

Nucleotide		Protein
Heading	Accession and Version	Protein
genomic	AL160006.16	CAI22715.1
		CAI22716.1
genomic	AL772411.1	CAH70967.1
		CAH70968.1
genomic	CH471122.1	EAW56428.1
		EAW56429.1
mRNA	AB051548.2	BAB21852.2
mRNA	AK027649.1	BAB55265.1
mRNA	AK098023.1	None
mRNA	AK125054.1	BAC86034.1
mRNA	AK291059.1	BAF83748.1
mRNA	AL834196.1	CAH56368.1
mRNA	BC019919.1	AAH19919.1
mRNA	BC032644.1	AAH32644.1
mRNA	BC040142.1	None
mRNA	BC067239.1	None
mRNA	BC094786.1	AAH94786.1
mRNA	BC119814.1	AAI19815.1
mRNA	BC121793.1	AAI21794.1
mRNA	CB960147.1	None

Protein Accession	Links
Protein Accession	GenPept Link	UniProtKB Link
Q5VSL9.1	GenPept	UniProtKB/Swiss-Prot:Q5VSL9
Q6ZU72	GenPept	UniProtKB/TrEMBL:Q6ZU72
Q8WUN4	GenPept	UniProtKB/TrEMBL:Q8WUN4