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SAC1 phosphatidylinositol-3-phosphatase SAC1 [ Saccharomyces cerevisiae S288c ]

Gene ID: 853668, updated on 3-Apr-2016
Gene symbol
SAC1
Gene description
phosphatidylinositol-3-phosphatase SAC1
Primary source
SGD:S000001695
Locus tag
YKL212W
Gene type
protein coding
RNA name
phosphatidylinositol-3-phosphatase SAC1
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
RSD1
See SAC1 in Map Viewer
Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (34543..36414)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene Yra2p Neighboring gene Doa1p Neighboring gene bifunctional anthranilate synthase/indole-3-glycerol-phosphate synthase Neighboring gene ncRNA

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

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  • 3-phosphoinositide biosynthesis, organism-specific biosystem (from BIOCYC)
    3-phosphoinositide biosynthesis, organism-specific biosystem
    3-phosphoinositide biosynthesis
  • 3-phosphoinositide biosynthesis, conserved biosystem (from BIOCYC)
    3-phosphoinositide biosynthesis, conserved biosystem|FRAME: Phosphoinositides "Phosphoinositides"| play a key role in signal transduction in the eukaryotic cell, transmitting signals from the cell surface to modulate intracellular processes. One well ...
  • 3-phosphoinositide degradation, conserved biosystem (from BIOCYC)
    3-phosphoinositide degradation, conserved biosystem|FRAME: Phosphoinositides "Phosphoinositides"| play a key role in signal transduction in the eukaryotic cell, transmitting signals from the cell surface to modulate intracellular processes. The 3-pho...
  • phosphatidylinositol phosphate biosynthesis, organism-specific biosystem (from BIOCYC)
    phosphatidylinositol phosphate biosynthesis, organism-specific biosystemThe phosphorylated products of phosphatidylinositol (PtdIns, PI), collectively referred to as phosphoinositides or phosphatidylinositol phosphates (PtdInsPs, PIPs), are membrane-bound lipids that fun...
  • superpathway of inositol phosphate compounds, conserved biosystem (from BIOCYC)
    superpathway of inositol phosphate compounds, conserved biosystemThe phosphorylated inositol compounds described in this superpathway can be divided into two major groups - the phospholipids phosphatidyl inositols, and the cyclitols inositol phosphates. The most ...
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
phosphatase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
phosphatidylinositol-3-phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
phosphatidylinositol-4-phosphate phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
phosphoric ester hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
phosphatidylinositol dephosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
phosphatidylinositol dephosphorylation IGI
Inferred from Genetic Interaction
more info
PubMed 
phosphatidylinositol dephosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Golgi medial cisterna IDA
Inferred from Direct Assay
more info
PubMed 
SPOTS complex IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of Golgi membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of Golgi membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
integral component of endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of endoplasmic reticulum membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial outer membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
Names
phosphatidylinositol-3-phosphatase SAC1
NP_012710.1
  • Phosphatidylinositol phosphate (PtdInsP) phosphatase; involved in hydrolysis of PtdIns[4]P in the early and medial Golgi; regulated by interaction with Vps74p; ER localized transmembrane protein which cycles through the Golgi; involved in protein trafficking and processing, secretion, and cell wall maintenance; regulates sphingolipid biosynthesis through the modulation of PtdIns(4)P metabolism

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    34543..36414
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179777.1NP_012710.1  phosphatidylinositol-3-phosphatase SAC1 [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_012710.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P32368
    Conserved Domains (2) summary
    COG5329
    Location:3578
    COG5329; Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
    pfam02383
    Location:55348
    Syja_N; SacI homology domain