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SAC1 phosphatidylinositol-3-phosphatase SAC1 [ Saccharomyces cerevisiae S288c ]

Gene ID: 853668, updated on 22-Jul-2014
Gene symbol
SAC1
Gene description
phosphatidylinositol-3-phosphatase SAC1
Primary source
SGD:S000001695
Locus tag
YKL212W
Gene type
protein coding
RNA name
phosphatidylinositol-3-phosphatase SAC1
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
RSD1
See SAC1 in MapViewer
Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (34543..36414)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene Yra2p Neighboring gene Doa1p Neighboring gene bifunctional anthranilate synthase/indole-3-glycerol-phosphate synthase Neighboring gene ncRNA

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
phosphatase activity IMP
Inferred from Mutant Phenotype
more info
 
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
phosphatidylinositol-3-phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
phosphatidylinositol-4-phosphate phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
phosphoric ester hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
phosphatidylinositol dephosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
phosphatidylinositol dephosphorylation IGI
Inferred from Genetic Interaction
more info
PubMed 
phosphatidylinositol dephosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Golgi medial cisterna IDA
Inferred from Direct Assay
more info
 
SPOTS complex IDA
Inferred from Direct Assay
more info
 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of Golgi membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of Golgi membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
integral component of endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of endoplasmic reticulum membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial outer membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
Names
phosphatidylinositol-3-phosphatase SAC1
NP_012710.1
  • Phosphatidylinositol phosphate (PtdInsP) phosphatase; involved in hydrolysis of PtdIns[4]P in the early and medial Golgi; regulated by interaction with Vps74p; ER localized transmembrane protein which cycles through the Golgi; involved in protein trafficking and processing, secretion, and cell wall maintenance; regulates sphingolipid biosynthesis through the modulation of PtdIns(4)P metabolism

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 

    Range
    34543..36414
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179777.1NP_012710.1  phosphatidylinositol-3-phosphatase SAC1 [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_012710.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P32368
    Conserved Domains (2) summary
    COG5329
    Location:3578
    Blast Score: 1788
    COG5329; Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
    pfam02383
    Location:55348
    Blast Score: 923
    Syja_N; SacI homology domain