These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
Genomic
-
NG_029122.1 RefSeqGene
- Range
- 5001..26915
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_033034.2 → NP_149023.2 tripartite motif-containing protein 5 isoform alpha
Status: REVIEWED
- Description
- Transcript Variant: This variant (alpha) encodes the longest isoform (alpha).
- Source sequence(s)
-
AC015691, AK027593, CN334837, DA475412
- Consensus CDS
-
CCDS31393.1
- UniProtKB/Swiss-Prot
-
Q9C035
- Related
- ENSP00000369373, OTTHUMP00000069811, ENST00000380034, OTTHUMT00000143360
- Conserved Domains (5) summary
-
- cd00021
Location:93 – 130
Blast Score: 101
- BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
- cd00162
Location:14 – 59
Blast Score: 116
- RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
- pfam01496
Location:178 – 256
Blast Score: 88
- V_ATPase_I; V-type ATPase 116kDa subunit family
- pfam13923
Location:11 – 59
Blast Score: 111
- zf-C3HC4_2; Zinc finger, C3HC4 type (RING finger)
- cl02614
Location:356 – 491
Blast Score: 209
- SPRY; SPRY domain
-
NM_033092.2 → NP_149083.2 tripartite motif-containing protein 5 isoform gamma
Status: REVIEWED
- Description
- Transcript Variant: This variant (gamma) includes an alternate segment in the 3' coding region, compared to variant alpha, which results in a frameshift. The resulting protein (isoform gamma) has a shorter and distinct C-terminus, compared to isoform alpha.
- Source sequence(s)
-
AC015691, AF220027, AK074363, BC021258, CN334837, DA475412
- Consensus CDS
-
CCDS31394.1
- UniProtKB/Swiss-Prot
-
Q9C035
- Related
- ENSP00000380058, OTTHUMP00000069813, ENST00000396847, OTTHUMT00000143363
- Conserved Domains (4) summary
-
- cd00021
Location:93 – 130
Blast Score: 97
- BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
- cd00162
Location:14 – 59
Blast Score: 116
- RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
- pfam01496
Location:178 – 256
Blast Score: 89
- V_ATPase_I; V-type ATPase 116kDa subunit family
- pfam13923
Location:11 – 59
Blast Score: 112
- zf-C3HC4_2; Zinc finger, C3HC4 type (RING finger)
-
NM_033093.2 → NP_149084.2 tripartite motif-containing protein 5 isoform delta
Status: REVIEWED
- Description
- Transcript Variant: This variant (delta) differs in the 5' UTR and uses an alternate splice site in the 3' terminal exon, which results in a frameshift, compared to variant alpha. The encoded isoform (delta) has a shorter and distinct C-terminus, compared to isoform alpha.
- Source sequence(s)
-
AC015691, AC109341, DA475412
- Consensus CDS
-
CCDS31392.1
- UniProtKB/Swiss-Prot
-
Q9C035
- Related
- ENSP00000380064, ENST00000396855
- Conserved Domains (4) summary
-
- cd00021
Location:93 – 130
Blast Score: 101
- BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
- cd00162
Location:14 – 59
Blast Score: 122
- RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
- pfam01496
Location:178 – 256
Blast Score: 88
- V_ATPase_I; V-type ATPase 116kDa subunit family
- pfam13923
Location:11 – 59
Blast Score: 118
- zf-C3HC4_2; Zinc finger, C3HC4 type (RING finger)
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000011.9 Reference GRCh37.p5 Primary Assembly
- Range
- 5684425..5706339, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000143.1 Alternate HuRef
- Range
- 5344050..5365972, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)