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    MCM22 Mcm22p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 853599, updated on 6-May-2012
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    Summary

    Gene symbol
    MCM22
    Gene description
    Mcm22p
    Primary source
    SGD:S000003896
    Locus tag
    YJR135C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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    Genomic context

    Location :
    chromosome: X
    Sequence :
    Chromosome: X; NC_001142.9 (676059..676778, complement)
    See MCM22 in MapViewer

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Xpt1p Neighboring gene Sgm1p Neighboring gene Tim8p Neighboring gene Tti2p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Sharifpoor S, et al. Genome Res, 2012 Apr. PMID 22282571.
    2. A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. Hoppins S, et al. J Cell Biol, 2011 Oct 17. PMID 21987634.
    3. Misregulation of Scm3p/HJURP causes chromosome instability in Saccharomyces cerevisiae and human cells. Mishra PK, et al. PLoS Genet, 2011 Sep. PMID 21980305.
    4. Srs2 overexpression reveals a helicase-independent role at replication forks that requires diverse cell functions. León Ortiz AM, et al. DNA Repair (Amst), 2011 May 5. PMID 21459050.
    5. Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. Reid RJ, et al. Genome Res, 2011 Mar. PMID 21173034.

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:33890 BioGRID:33177 AFT1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:33890 BioGRID:32908 AME1    BioGRID  PubMed Affinity Capture-MS; Negative Genetic 
    BioGRID:33890 BioGRID:34950 APQ12    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:33890 BioGRID:36440 ARD1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:33890 BioGRID:31358 ARP6    BioGRID  PubMed Synthetic Lethality 
    BioGRID:33890 BioGRID:35908 BBP1    BioGRID  PubMed Two-hybrid 
    BioGRID:33890 BioGRID:36749 BIM1    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:33890 BioGRID:33440 BUB1    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:33890 BioGRID:34429 BUB3    BioGRID  PubMed Negative Genetic; Positive Genetic; Synthetic Lethality 
    BioGRID:33890 BioGRID:33386 CBF2    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:33890 BioGRID:36169 CHL1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:33890 BioGRID:32304 CHL4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:33890 BioGRID:35376 CIK1    BioGRID  PubMed Affinity Capture-MS; Negative Genetic 
    BioGRID:33890 BioGRID:36668 CIN8    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:33890 BioGRID:32207 CPR1    BioGRID  PubMed Two-hybrid 
    BioGRID:33890 BioGRID:34084 CSE4    BioGRID  PubMed Synthetic Lethality 
    BioGRID:33890 BioGRID:35269 CTF13    BioGRID  PubMed Synthetic Lethality 
    BioGRID:33890 BioGRID:36159 CTF19    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:33890 BioGRID:31640 CTF3    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Two-hybrid 
    BioGRID:33890 BioGRID:36302 CTF4    BioGRID  PubMed Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:33890 BioGRID:32066 DAD1    BioGRID  PubMed Two-hybrid 
    BioGRID:33890 BioGRID:35002 DSN1    BioGRID  PubMed Affinity Capture-MS; Negative Genetic 
    BioGRID:33890 BioGRID:32654 ECM13    BioGRID  PubMed Two-hybrid 
    BioGRID:33890 BioGRID:32734 EDS1    BioGRID  PubMed Positive Genetic 
    BioGRID:33890 BioGRID:35676 GIM3    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:33890 BioGRID:36728 GIM4    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:33890 BioGRID:35049 GIM5    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:33890 BioGRID:36877 GLC7    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:33890 BioGRID:33656 GSH1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:33890 BioGRID:32710 HHF1    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:33063 HOS2    BioGRID  PubMed Positive Genetic 
    BioGRID:33890 BioGRID:32277 HTA1    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:33848 IME1    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:32811 IML3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:33890 BioGRID:35976 IPL1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:33890 BioGRID:36310 KAR3    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:33890 BioGRID:32581 KRE28    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:33164 MAD1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:33890 BioGRID:33729 MAD2    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:33890 BioGRID:32051 MCD1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:33890 BioGRID:36222 MCM16    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Two-hybrid 
    BioGRID:33890 BioGRID:32374 MCM21    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:33890 BioGRID:36009 NIP100    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:33890 BioGRID:32444 NKP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:33890 BioGRID:31580 NKP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:33890 BioGRID:35266 NPL6    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:33890 BioGRID:35929 NSL1    BioGRID  PubMed Affinity Capture-MS; Negative Genetic 
    BioGRID:33890 BioGRID:31946 NUP84    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:33102 NUT1    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:35724 OCA1    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:34002 OCT1    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:33431 OKP1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:33890 BioGRID:33320 PAC10    BioGRID  PubMed Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:33890 BioGRID:31719 PAU4    BioGRID  PubMed Positive Genetic 
    BioGRID:33890 BioGRID:33628 PBS2    BioGRID  PubMed Positive Genetic 
    BioGRID:33890 BioGRID:32694 PDR3    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:32170 PDS1    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:33582 PFD1    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:34403 PHO80    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:33890 BioGRID:35105 PIF1    BioGRID  PubMed Dosage Growth Defect 
    BioGRID:33890 BioGRID:35300 PKR1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:33890 BioGRID:34349 PSH1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:33890 BioGRID:32065 RAD61    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:33890 BioGRID:33301 RSC1    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:32600 RTG3    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:32342 RTT103    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:33890 BioGRID:32234 SCC2    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:31922 SCM3    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:33890 BioGRID:32420 SEM1    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:34162 SET3    BioGRID  PubMed Positive Genetic 
    BioGRID:33890 BioGRID:32041 SLX5    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:31139 SMC1    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:33681 SMC3    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:35187 SOK2    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:33153 SRM1    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:33665 SRS2    BioGRID  PubMed Dosage Lethality 
    BioGRID:33890 BioGRID:32663 STU1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:33890 BioGRID:32363 SUM1    BioGRID  PubMed Dosage Rescue 
    BioGRID:33890 BioGRID:32376 SWA2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:33890 BioGRID:31453 SWI6    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:35586 TEX1    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:34398 TOP1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:33890 BioGRID:35056 TUB1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:33890 BioGRID:31463 UPS1    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:36702 VMA3    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:35717 YAF9    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:31796 YAR010C    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:33890 BioGRID:35924 YAR1    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:33187 YBP2    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:33890 BioGRID:31886 YDL180W    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:31469 YKE2    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:33890 BioGRID:31339 YLR065C    BioGRID  PubMed Negative Genetic 
    BioGRID:33890 BioGRID:31508 YLR241W    BioGRID  PubMed Two-hybrid 
    BioGRID:33890 BioGRID:33698 ZAP1    BioGRID  PubMed Positive Genetic 
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    General gene information

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    chromosome segregation IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    establishment of mitotic sister chromatid cohesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    meiosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    mitosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
    		  
    condensed chromosome kinetochore IEA
    Inferred from Electronic Annotation
    more info
    		  
    condensed nuclear chromosome kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    kinetochore IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Names
    Mcm22p
    NP_012669.1
    • Protein involved in minichromosome maintenance; component of the kinetochore; binds to centromeric DNA in a Ctf19p-dependent manner
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9

      Range
      676059..676778, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181793.1 → NP_012669.1  Mcm22p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P47167
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006943.2 DAA08919.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47167.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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