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MES1 methionine--tRNA ligase MES1 [ Saccharomyces cerevisiae S288c ]

Gene ID: 853181, updated on 7-Dec-2014
Gene symbol
MES1
Gene description
methionine--tRNA ligase MES1
Primary source
SGD:S000003496
Locus tag
YGR264C
Gene type
protein coding
RNA name
methionine--tRNA ligase MES1
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See MES1 in MapViewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (1019598..1021853, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Bud32p Neighboring gene Say1p Neighboring gene hypothetical protein Neighboring gene GTP cyclohydrolase I

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
aminoacyl-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
ligase activity IEA
Inferred from Electronic Annotation
more info
 
methionine-tRNA ligase activity IDA
Inferred from Direct Assay
more info
PubMed 
methionine-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
methionyl-tRNA aminoacylation IDA
Inferred from Direct Assay
more info
PubMed 
methionyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 
tRNA aminoacylation for protein translation IEA
Inferred from Electronic Annotation
more info
 
translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
methionyl glutamyl tRNA synthetase complex IDA
Inferred from Direct Assay
more info
PubMed 
Names
methionine--tRNA ligase MES1
NP_011780.3
  • Methionyl-tRNA synthetase; forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 

    Range
    1019598..1021853
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181393.3NP_011780.3  methionine--tRNA ligase MES1 [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_011780.3

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P00958
    Conserved Domains (4) summary
    cd07957
    Location:574703
    Anticodon_Ia_Met; Anticodon-binding domain of methionyl tRNA synthetases
    cd00814
    Location:197565
    MetRS_core; catalytic core domain of methioninyl-tRNA synthetases
    cd10290
    Location:62156
    GST_C_MetRS_N_fungi; Glutathione S-transferase C-terminal-like, alpha helical domain of Saccharomycetales Methionyl-tRNA synthetase
    TIGR00398
    Location:198735
    metG; methionyl-tRNA synthetase