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RAD2 ssDNA endodeoxyribonuclease RAD2 [ Saccharomyces cerevisiae S288c ]

Gene ID: 853174, updated on 7-Aug-2016
Gene symbol
RAD2
Gene description
ssDNA endodeoxyribonuclease RAD2
Primary source
SGD:S000003490
Locus tag
YGR258C
Gene type
protein coding
RNA name
ssDNA endodeoxyribonuclease RAD2
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See RAD2 in Map Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (1007671..1010766, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene phosphogluconate dehydrogenase (decarboxylating) GND2 Neighboring gene Mtm1p Neighboring gene Tna1p Neighboring gene Apl6p

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
endonuclease activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity, acting on ester bonds IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nuclease activity IEA
Inferred from Electronic Annotation
more info
 
single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 
single-stranded DNA endodeoxyribonuclease activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
DNA repair IEA
Inferred from Electronic Annotation
more info
 
cellular response to DNA damage stimulus IEA
Inferred from Electronic Annotation
more info
 
nucleotide-excision repair IEA
Inferred from Electronic Annotation
more info
 
nucleotide-excision repair, DNA incision, 3'-to lesion IDA
Inferred from Direct Assay
more info
PubMed 
nucleotide-excision repair, DNA incision, 3'-to lesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription from RNA polymerase II promoter IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
nucleotide-excision repair factor 3 complex IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
ssDNA endodeoxyribonuclease RAD2
NP_011774.1
  • Single-stranded DNA endonuclease; cleaves single-stranded DNA during nucleotide excision repair to excise damaged DNA; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPG protein

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    1007671..1010766 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181387.1NP_011774.1  ssDNA endodeoxyribonuclease RAD2 [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_011774.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P07276
    Conserved Domains (3) summary
    cd09904
    Location:852945
    H3TH_XPG; H3TH domain of Xeroderma pigmentosum complementation group G (XPG) nuclease, a structure-specific, divalent-metal-ion dependent, 5' nuclease
    cd09868
    Location:1117
    PIN_XPG; PIN domain of Xeroderma pigmentosum complementation group G (XPG) nuclease, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs
    TIGR00600
    Location:11030
    rad2; DNA excision repair protein (rad2)