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SKI6 Ski6p [ Saccharomyces cerevisiae S288c ]

Gene ID: 853109, updated on 22-Jul-2014
Gene symbol
SKI6
Gene description
Ski6p
Primary source
SGD:S000003427
Locus tag
YGR195W
Gene type
protein coding
RNA name
Ski6p
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
ECM20; RRP41
See SKI6 in MapViewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (888882..889622)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Pdx1p Neighboring gene xylulokinase Neighboring gene Fyv8p Neighboring gene Sng1p

  • Exosome, archaea, organism-specific biosystem (from KEGG)
    Exosome, archaea, organism-specific biosystemStructural complex; Genetic information processing; RNA processing
  • Exosome, archaea, conserved biosystem (from KEGG)
    Exosome, archaea, conserved biosystemStructural complex; Genetic information processing; RNA processing
  • Exosome, eukaryotes, organism-specific biosystem (from KEGG)
    Exosome, eukaryotes, organism-specific biosystemStructural complex; Genetic information processing; RNA processing
  • Exosome, eukaryotes, conserved biosystem (from KEGG)
    Exosome, eukaryotes, conserved biosystemStructural complex; Genetic information processing; RNA processing
  • RNA degradation, organism-specific biosystem (from KEGG)
    RNA degradation, organism-specific biosystemThe correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay e...
  • RNA degradation, conserved biosystem (from KEGG)
    RNA degradation, conserved biosystemThe correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay e...
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
RNA binding IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
U1 snRNA 3'-end processing IGI
Inferred from Genetic Interaction
more info
PubMed 
U1 snRNA 3'-end processing IMP
Inferred from Mutant Phenotype
more info
PubMed 
U4 snRNA 3'-end processing IGI
Inferred from Genetic Interaction
more info
PubMed 
U4 snRNA 3'-end processing IMP
Inferred from Mutant Phenotype
more info
PubMed 
U5 snRNA 3'-end processing IGI
Inferred from Genetic Interaction
more info
PubMed 
U5 snRNA 3'-end processing IMP
Inferred from Mutant Phenotype
more info
PubMed 
exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
Inferred from Mutant Phenotype
more info
PubMed 
nonfunctional rRNA decay IC
Inferred by Curator
more info
PubMed 
nuclear mRNA surveillance IGI
Inferred from Genetic Interaction
more info
PubMed 
nuclear mRNA surveillance IMP
Inferred from Mutant Phenotype
more info
PubMed 
nuclear polyadenylation-dependent CUT catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
nuclear polyadenylation-dependent mRNA catabolic process IC
Inferred by Curator
more info
PubMed 
nuclear polyadenylation-dependent tRNA catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay IGI
Inferred from Genetic Interaction
more info
PubMed 
nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay IMP
Inferred from Mutant Phenotype
more info
PubMed 
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' IMP
Inferred from Mutant Phenotype
more info
PubMed 
nuclear-transcribed mRNA catabolic process, non-stop decay IC
Inferred by Curator
more info
PubMed 
polyadenylation-dependent snoRNA 3'-end processing IMP
Inferred from Mutant Phenotype
more info
PubMed 
rRNA catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
rRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic exosome (RNase complex) IDA
Inferred from Direct Assay
more info
PubMed 
exosome (RNase complex) IEA
Inferred from Electronic Annotation
more info
 
nuclear exosome (RNase complex) IDA
Inferred from Direct Assay
more info
PubMed 
nucleolus IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
Ski6p
NP_011711.3
  • Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp41p (EXOSC4)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 

    Range
    888882..889622
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181324.3NP_011711.3  Ski6p [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_011711.3

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P46948
    Conserved Domains (2) summary
    cd11370
    Location:11237
    Blast Score: 841
    RNase_PH_RRP41; RRP41 subunit of eukaryotic exosome
    COG0689
    Location:5233
    Blast Score: 627
    Rph; RNase PH [Translation, ribosomal structure and biogenesis]