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PRE9 proteasome core particle subunit alpha 3 [ Saccharomyces cerevisiae S288c ]

Gene ID: 853036, updated on 16-Jan-2015
Gene symbol
PRE9
Gene description
proteasome core particle subunit alpha 3
Primary source
SGD:S000003367
Locus tag
YGR135W
Gene type
protein coding
RNA name
proteasome core particle subunit alpha 3
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See PRE9 in MapViewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (761392..762168)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene E2 ubiquitin-protein ligase peroxin 4 Neighboring gene CCR4-NOT core subunit CAF130 Neighboring gene Lsb1p Neighboring gene Tpo2p

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
peptidase activity IEA
Inferred from Electronic Annotation
more info
 
threonine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
proteasomal ubiquitin-independent protein catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
proteasome core complex assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
proteasome-mediated ubiquitin-dependent protein catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
proteolysis IEA
Inferred from Electronic Annotation
more info
 
proteolysis involved in cellular protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nuclear outer membrane-endoplasmic reticulum membrane network IC
Inferred by Curator
more info
PubMed 
nucleus IC
Inferred by Curator
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
proteasome complex IEA
Inferred from Electronic Annotation
more info
 
proteasome core complex IEA
Inferred from Electronic Annotation
more info
 
proteasome core complex, alpha-subunit complex IDA
Inferred from Direct Assay
more info
PubMed 
proteasome core complex, alpha-subunit complex IEA
Inferred from Electronic Annotation
more info
 
proteasome storage granule IDA
Inferred from Direct Assay
more info
PubMed 
Names
proteasome core particle subunit alpha 3
NP_011651.3
  • Alpha 3 subunit of the 20S proteasome; the only nonessential 20S subunit; may be replaced by the alpha 4 subunit (Pre6p) under stress conditions to create a more active proteasomal isoform

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 

    Range
    761392..762168
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181264.3NP_011651.3  proteasome core particle subunit alpha 3 [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_011651.3

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P23638
    Conserved Domains (2) summary
    PTZ00246
    Location:3241
    PTZ00246; proteasome subunit alpha; Provisional
    cd03752
    Location:4216
    proteasome_alpha_type_4; proteasome_alpha_type_4. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on ...