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ASN2 asparagine synthase (glutamine-hydrolyzing) 2 [ Saccharomyces cerevisiae S288c ]

Gene ID: 853025, updated on 7-Sep-2014
Gene symbol
ASN2
Gene description
asparagine synthase (glutamine-hydrolyzing) 2
Primary source
SGD:S000003356
Locus tag
YGR124W
Gene type
protein coding
RNA name
asparagine synthase (glutamine-hydrolyzing) 2
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See ASN2 in MapViewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (739944..741662)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Ppt1p Neighboring gene tRNA Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
asparagine synthase (glutamine-hydrolyzing) activity IDA
Inferred from Direct Assay
more info
PubMed 
asparagine synthase (glutamine-hydrolyzing) activity IEA
Inferred from Electronic Annotation
more info
 
asparagine synthase (glutamine-hydrolyzing) activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
ligase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
L-asparagine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
asparagine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
asparagine biosynthetic process IGI
Inferred from Genetic Interaction
more info
PubMed 
cellular amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
glutamine metabolic process IEA
Inferred from Electronic Annotation
more info
 
metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
Names
asparagine synthase (glutamine-hydrolyzing) 2
NP_011640.1
  • Asparagine synthetase; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway; ASN2 has a paralog, ASN1, that arose from the whole genome duplication

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 

    Range
    739944..741662
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181253.1NP_011640.1  asparagine synthase (glutamine-hydrolyzing) 2 [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_011640.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P49090
    Conserved Domains (3) summary
    PRK09431
    Location:1561
    asnB; asparagine synthetase B; Provisional
    cd00712
    Location:2193
    AsnB; Glutamine amidotransferases class-II (GATase) asparagine synthase_B type. Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a glutaminase domain and a ...
    cd01991
    Location:213484
    Asn_Synthase_B_C; The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the ...