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DBF2 serine/threonine-protein kinase DBF2 [ Saccharomyces cerevisiae S288c ]

Gene ID: 852984, updated on 16-Jul-2015
Gene symbol
DBF2
Gene description
serine/threonine-protein kinase DBF2
Primary source
SGD:S000003324
Locus tag
YGR092W
Gene type
protein coding
RNA name
serine/threonine-protein kinase DBF2
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See DBF2 in MapViewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (668189..669907)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Utp22p Neighboring gene Prp31p Neighboring gene Drn1p Neighboring gene valine--tRNA ligase

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Cell Cycle and Cell Division, organism-specific biosystem (from WikiPathways)
    Cell Cycle and Cell Division, organism-specific biosystem(From http://en.wikipedia.org/wiki/Cell_cycle) The cell cycle is the series of events that takes place in a cell leading to its division and duplication (replication). Regulation of the cell cycle in...
  • Cell cycle - yeast, organism-specific biosystem (from KEGG)
    Cell cycle - yeast, organism-specific biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps (G1 and G2 phases). G1, S, and G...
  • Cell cycle - yeast, conserved biosystem (from KEGG)
    Cell cycle - yeast, conserved biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps (G1 and G2 phases). G1, S, and G...
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
RNA binding IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity, transferring phosphorus-containing groups IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell cycle IEA
Inferred from Electronic Annotation
more info
 
nuclear division IMP
Inferred from Mutant Phenotype
more info
PubMed 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cytokinesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
vacuolar acidification IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cellular bud neck IDA
Inferred from Direct Assay
more info
PubMed 
cellular bud neck IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
spindle pole body IDA
Inferred from Direct Assay
more info
PubMed 
spindle pole body IEA
Inferred from Electronic Annotation
more info
 
Names
serine/threonine-protein kinase DBF2
NP_011606.3
  • Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs; phosphorylates Chs2p to regulate primary septum formation and Hof1p to regulate cytokinesis; DBF2 has a paralog, DBF20, that arose from the whole genome duplication

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    668189..669907
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181221.3NP_011606.3  serine/threonine-protein kinase DBF2 [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_011606.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P22204
    Conserved Domains (2) summary
    smart00220
    Location:177477
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd05600
    Location:165547
    STKc_Sid2p_like; Catalytic domain of Fungal Sid2p-like Protein Serine/Threonine Kinases