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RAD54 DNA-dependent ATPase RAD54 [ Saccharomyces cerevisiae S288c ]

Gene ID: 852713, updated on 6-Jul-2014
Gene symbol
RAD54
Gene description
DNA-dependent ATPase RAD54
Primary source
SGD:S000003131
Locus tag
YGL163C
Gene type
protein coding
RNA name
DNA-dependent ATPase RAD54
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
XRS1
See RAD54 in MapViewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (193707..196403, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Cup2p Neighboring gene Yrb30p Neighboring gene Sut1p Neighboring gene Yip5p

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Homologous recombination, organism-specific biosystem (from KEGG)
    Homologous recombination, organism-specific biosystemHomologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves...
  • Homologous recombination, conserved biosystem (from KEGG)
    Homologous recombination, conserved biosystemHomologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves...
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA translocase activity IDA
Inferred from Direct Assay
more info
PubMed 
DNA-dependent ATPase activity IDA
Inferred from Direct Assay
more info
PubMed 
helicase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity, acting on acid anhydrides IEA
Inferred from Electronic Annotation
more info
 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
DNA geometric change IDA
Inferred from Direct Assay
more info
PubMed 
DNA repair IEA
Inferred from Electronic Annotation
more info
 
cellular response to DNA damage stimulus IEA
Inferred from Electronic Annotation
more info
 
chromatin remodeling IDA
Inferred from Direct Assay
more info
PubMed 
NOT double-strand break repair via single-strand annealing IMP
Inferred from Mutant Phenotype
more info
PubMed 
double-strand break repair via synthesis-dependent strand annealing TAS
Traceable Author Statement
more info
PubMed 
heteroduplex formation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of endodeoxyribonuclease activity IDA
Inferred from Direct Assay
more info
PubMed 
telomere maintenance via recombination IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IDA
Inferred from Direct Assay
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
nucleus IMP
Inferred from Mutant Phenotype
more info
PubMed 
Names
DNA-dependent ATPase RAD54
NP_011352.1
  • DNA-dependent ATPase that stimulates strand exchange; modifies the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family; forms nuclear foci upon DNA replication stress

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 

    Range
    193707..196403
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181028.1NP_011352.1  DNA-dependent ATPase RAD54 [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_011352.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P32863
    Conserved Domains (4) summary
    cd00046
    Location:330486
    Blast Score: 205
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:654778
    Blast Score: 249
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:274621
    Blast Score: 790
    SNF2_N; SNF2 family N-terminal domain
    pfam08658
    Location:23262
    Blast Score: 538
    Rad54_N; Rad54 N terminal