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CHC1 clathrin heavy chain [ Saccharomyces cerevisiae S288c ]

Gene ID: 852666, updated on 7-Sep-2014
Gene symbol
CHC1
Gene description
clathrin heavy chain
Primary source
SGD:S000003174
Locus tag
YGL206C
Gene type
protein coding
RNA name
clathrin heavy chain
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
SWA5
See CHC1 in MapViewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (102543..107504, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Sip2p Neighboring gene chromatin-remodeling protein SPT16 Neighboring gene acyl-CoA oxidase Neighboring gene tRNA

  • Endocytosis, organism-specific biosystem (from KEGG)
    Endocytosis, organism-specific biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
  • Endocytosis, conserved biosystem (from KEGG)
    Endocytosis, conserved biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
structural molecule activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
endocytosis IDA
Inferred from Direct Assay
more info
PubMed 
endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 
vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
vesicle-mediated transport TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
clathrin coat of coated pit IEA
Inferred from Electronic Annotation
more info
 
clathrin coat of trans-Golgi network vesicle IEA
Inferred from Electronic Annotation
more info
 
clathrin vesicle coat TAS
Traceable Author Statement
more info
PubMed 
coated pit IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic vesicle membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
Names
clathrin heavy chain
NP_011309.1
  • Clathrin heavy chain; subunit of the major coat protein involved in intracellular protein transport and endocytosis; the clathrin triskelion is a trimeric molecule composed of three heavy chains that radiate from a vertex and three light chains which bind noncovalently near the vertex of the triskelion; the light chain (CLC1) is thought to regulate function

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 

    Range
    102543..107504
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181071.1NP_011309.1  clathrin heavy chain [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_011309.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P22137
    Conserved Domains (4) summary
    smart00299
    Location:12801422
    Blast Score: 343
    CLH; Clathrin heavy chain repeat homology
    pfam00637
    Location:11381274
    Blast Score: 304
    Clathrin; Region in Clathrin and VPS
    pfam09268
    Location:338360
    Blast Score: 86
    Clathrin-link; Clathrin, heavy-chain linker
    pfam13838
    Location:362425
    Blast Score: 264
    Clathrin_H_link; Clathrin-H-link