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MED8 Med8p [ Saccharomyces cerevisiae S288c ]

Gene ID: 852492, updated on 18-Feb-2015
Gene symbol
MED8
Gene description
Med8p
Primary source
SGD:S000000397
Locus tag
YBR193C
Gene type
protein coding
RNA name
Med8p
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See MED8 in MapViewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (609082..609753, complement)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene ribosomal 60S subunit protein L21A Neighboring gene Rim2p Neighboring gene Aim4p Neighboring gene Msi1p

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II core promoter proximal region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase II transcription cofactor activity IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II transcription corepressor activity IPI
Inferred from Physical Interaction
more info
PubMed 
TBP-class protein binding IDA
Inferred from Direct Assay
more info
PubMed 
structural molecule activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
core mediator complex IDA
Inferred from Direct Assay
more info
PubMed 
mediator complex IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
Med8p
NP_009752.3
  • Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    609082..609753
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178541.3NP_009752.3  Med8p [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_009752.3

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P38304
    Conserved Domains (1) summary
    pfam10232
    Location:31211
    Med8; Mediator of RNA polymerase II transcription complex subunit 8