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CNS1 Cns1p [ Saccharomyces cerevisiae S288c ]

Gene ID: 852452, updated on 25-Jul-2015
Gene symbol
CNS1
Gene description
Cns1p
Primary source
SGD:S000000359
Locus tag
YBR155W
Gene type
protein coding
RNA name
Cns1p
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See CNS1 in MapViewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (549771..550928)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase Neighboring gene DNA-directed RNA polymerase core subunit RPB5 Neighboring gene Sli15p Neighboring gene Ics2p

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
Hsp70 protein binding IDA
Inferred from Direct Assay
more info
PubMed 
Hsp90 protein binding IDA
Inferred from Direct Assay
more info
PubMed 
ribosome binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
protein folding IGI
Inferred from Genetic Interaction
more info
PubMed 
protein folding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IPI
Inferred from Physical Interaction
more info
PubMed 
Names
Cns1p
NP_009713.1
  • TPR-containing co-chaperone; binds both Hsp82p (Hsp90) and Ssa1p (Hsp70); stimulates ATPase activity of Ssa1p; ts mutants reduce Hsp82p function, overexpression suppresses phenotypes of HSP82 ts allele and cpr7 deletion; human homolog TTC4 complements yeast cns1 mutant

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    549771..550928
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178503.1NP_009713.1  Cns1p [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_009713.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P33313
    Conserved Domains (3) summary
    pfam00515
    Location:124154
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:81152
    TPR_11; TPR repeat
    sd00006
    Location:84167
    TPR; putative protein binding surface [polypeptide binding]