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    ECM2 Ecm2p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 852357, updated on 21-May-2012
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    Summary

    Gene symbol
    ECM2
    Gene description
    Ecm2p
    Primary source
    SGD:S000000269
    Locus tag
    YBR065C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    SLT11
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    Genomic context

    Location :
    chromosome: II
    Sequence :
    Chromosome: II; NC_001134.8 (368584..369678, complement)
    See ECM2 in MapViewer

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene Nrg2p Neighboring gene Tip1p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing. Mishra SK, et al. Nature, 2011 May 25. PMID 21614000.
    2. Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1Δ cells. Schwer B, et al. Nucleic Acids Res, 2011 Aug. PMID 21558325.
    3. The genetic landscape of a cell. Costanzo M, et al. Science, 2010 Jan 22. PMID 20093466.
    4. Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing. Lardelli RM, et al. RNA, 2010 Mar. PMID 20089683.
    5. A systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300. Khanna M, et al. RNA, 2009 Dec. PMID 19789211.

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:32768 BioGRID:35461 AEP2    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:36117 ALD6    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:36017 ATG29    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:32897 BEM1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:36925 BRR2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:36110 BTS1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:33079 BUD13    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:31040 BUD31    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:36005 CBC2    BioGRID  PubMed Affinity Capture-MS; Negative Genetic 
    BioGRID:32768 BioGRID:32421 CDC40    BioGRID  PubMed Synthetic Lethality 
    BioGRID:32768 BioGRID:35391 CEF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:36169 CHL1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:35641 CHS1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:32768 BioGRID:31389 CLF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:34433 CRS5    BioGRID  PubMed Positive Genetic 
    BioGRID:32768 BioGRID:31837 CWC2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:32534 CWC21    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:32768 BioGRID:36932 DMC1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:36476 DOG1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:36576 DSE2    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:33842 EMC2    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:31791 ERP1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:33671 EXO70    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:34857 FLX1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:31101 FMP32    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:33494 FMP43    BioGRID  PubMed Positive Genetic 
    BioGRID:32768 BioGRID:31894 GLT1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:36927 GRX4    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:33277 GSC2    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:34743 HAP5    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:31823 HBT1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:36054 HHO1    BioGRID  PubMed Positive Genetic 
    BioGRID:32768 BioGRID:33063 HOS2    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:32912 HPC2    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:35364 HSC82    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:31226 HSP104    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:35923 HSP82    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:35857 HUB1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:32768 BioGRID:34996 IST3    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:33803 ISY1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:30927 KRR1    BioGRID  PubMed Positive Genetic 
    BioGRID:32768 BioGRID:35972 LEA1    BioGRID  PubMed Affinity Capture-MS; Negative Genetic 
    BioGRID:32768 BioGRID:34594 LIP5    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:35833 LRO1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:31697 LSM3    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:32437 LSM6    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:36173 LSP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:32058 MAF1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:33500 MGA1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:31846 MGT1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:32172 MRPL1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:31143 MSH4    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:36301 MSS18    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:34179 NAP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:35489 NIP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:34952 NOT3    BioGRID  PubMed Positive Genetic 
    BioGRID:32768 BioGRID:33102 NUT1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:33344 PCP1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:33483 PHB2    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:31290 PML1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:32768 BioGRID:32867 POP7    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:34217 PRP16    BioGRID  PubMed Affinity Capture-MS; Synthetic Lethality 
    BioGRID:32768 BioGRID:31217 PRP19    BioGRID  PubMed Affinity Capture-MS; Co-purification; Negative Genetic 
    BioGRID:32768 BioGRID:35836 PRP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:36745 PRP22    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:36032 PRP46    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:36599 PRP8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:36834 PTC2    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:33185 PYC1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:36363 QCR2    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:35589 RAD50    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:34673 RDL2    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:31012 RIM1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:33203 RIM8    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:31268 RNP1    BioGRID  PubMed Positive Genetic 
    BioGRID:32768 BioGRID:33584 RPL17B    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:31921 RPO21    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:31978 RPS16B    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:32139 RRP8    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:32284 RTN1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:32449 RVS167    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:33078 SAE2    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:32144 SLU7    BioGRID  PubMed Affinity Capture-Western; Synthetic Lethality 
    BioGRID:32768 BioGRID:36764 SMB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:35840 SMM1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:36354 SMX3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:36267 SNT309    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:34697 SNU66    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:31683 SPP382    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:36498 SSF1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:32987 SUL1    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:33377 SYF2    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:32199 TAF12    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:35736 TCB2    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:36251 TEF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:34051 TEF4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:35322 TIF34    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:32487 TIF35    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32768 BioGRID:36893 UBP5    BioGRID  PubMed Positive Genetic 
    BioGRID:32768 BioGRID:32968 UBX7    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:34856 VHS2    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:36595 YAP1801    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:32933 YBR238C    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:32981 YBR287W    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:30917 YCL075W    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:300455 YDL118W    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:31886 YDL180W    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:36916 YER163C    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:31093 YFL054C    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:33003 YGL235W    BioGRID  PubMed Positive Genetic 
    BioGRID:32768 BioGRID:35249 YMR074C    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:35495 YMR315W    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:35815 YNL010W    BioGRID  PubMed Negative Genetic 
    BioGRID:32768 BioGRID:35692 YNL134C    BioGRID  PubMed Negative Genetic 
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    General gene information

    Pathways from BioSystems

    • Spliceosome, organism-specific biosystem (from KEGG)
      Spliceosome, organism-specific biosystemAfter transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, th...
    • Spliceosome, conserved biosystem (from KEGG)
      Spliceosome, conserved biosystemAfter transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, th...

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    nuclear mRNA splicing, via spliceosome IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Names
    Ecm2p
    NP_009621.1
    • Pre-mRNA splicing factor, facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome, function may be regulated by Slu7p
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8

      Range
      368584..369678, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178413.1 → NP_009621.1  TPA: Ecm2p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P38241
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006936.2 DAA07184.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38241.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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