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SNF1 AMP-activated serine/threonine-protein kinase catalytic subunit SNF1 [ Saccharomyces cerevisiae S288c ]

Gene ID: 852088, updated on 16-Nov-2014
Gene symbol
SNF1
Gene description
AMP-activated serine/threonine-protein kinase catalytic subunit SNF1
Primary source
SGD:S000002885
Locus tag
YDR477W
Gene type
protein coding
RNA name
AMP-activated serine/threonine-protein kinase catalytic subunit SNF1
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
CAT1; CCR1; GLC2; HAF3; PAS14
See SNF1 in MapViewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1412373..1414274)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Jip4p Neighboring gene hypothetical protein Neighboring gene Snm1p Neighboring gene Pex29p

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
AMP-activated protein kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity, transferring phosphorus-containing groups IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
cell adhesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to nitrogen starvation IDA
Inferred from Direct Assay
more info
PubMed 
fungal-type cell wall assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
invasive growth in response to glucose limitation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of translation IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of translation IMP
Inferred from Mutant Phenotype
more info
PubMed 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of filamentous growth of a population of unicellular organisms in response to starvation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of gluconeogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
pseudohyphal growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of carbohydrate metabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of carbohydrate metabolic process IPI
Inferred from Physical Interaction
more info
PubMed 
replicative cell aging IGI
Inferred from Genetic Interaction
more info
PubMed 
replicative cell aging IMP
Inferred from Mutant Phenotype
more info
PubMed 
single-species surface biofilm formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
AMP-activated protein kinase complex IDA
Inferred from Direct Assay
more info
PubMed 
AMP-activated protein kinase complex IPI
Inferred from Physical Interaction
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IPI
Inferred from Physical Interaction
more info
PubMed 
fungal-type vacuole IPI
Inferred from Physical Interaction
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
nuclear envelope lumen IDA
Inferred from Direct Assay
more info
PubMed 
nuclear membrane IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
nucleus IPI
Inferred from Physical Interaction
more info
PubMed 
Names
AMP-activated serine/threonine-protein kinase catalytic subunit SNF1
NP_010765.3
  • AMP-activated serine/threonine protein kinase; found in a complex containing Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; involved in regulation of the nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth in response to starvation; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ubiquitin ligase

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 

    Range
    1412373..1414274
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180785.3NP_010765.3  AMP-activated serine/threonine-protein kinase catalytic subunit SNF1 [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_010765.3

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P06782
    Conserved Domains (4) summary
    cd05123
    Location:61306
    STKc_AGC; Catalytic domain of AGC family Protein Serine/Threonine Kinases
    cd12122
    Location:502626
    AMPKA_C; C-terminal regulatory domain of 5'-AMP-activated protein kinase (AMPK) alpha catalytic subunit
    smart00220
    Location:55306
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    pfam08587
    Location:344389
    UBA_2; Ubiquitin associated domain (UBA)