Sign in to NCBI

Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information

    SNF1 Snf1p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 852088, updated on 21-May-2013
    Gene symbol
    SNF1
    Gene description
    Snf1p
    Primary source
    SGD:S000002885
    Locus tag
    YDR477W
    Gene type
    protein coding
    RNA name
    Snf1p
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    CAT1; CCR1; GLC2; HAF3; PAS14
    Location :
    chromosome: IV
    Sequence :
    Chromosome: IV; NC_001136.10 (1412373..1414274)
    See SNF1 in MapViewer

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Jip4p Neighboring gene hypothetical protein Neighboring gene Snm1p Neighboring gene Pex29p

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. The FOX transcription factor Hcm1 regulates oxidative metabolism in response to early nutrient limitation in yeast. Role of Snf1 and Tor1/Sch9 kinases. Rodríguez-Colman MJ, et al. Biochim Biophys Acta, 2013 Feb 26. PMID 23481038.
    2. The AMPK family member Snf1 protects Saccharomyces cerevisiae cells upon glutathione oxidation. Pérez-Sampietro M, et al. PLoS One, 2013. PMID 23472170.
    3. Mitochondrial porin Por1 and its homolog Por2 contribute to the positive control of Snf1 protein kinase in Saccharomyces cerevisiae. Strogolova V, et al. Eukaryot Cell, 2012 Dec. PMID 23104570.
    4. Phosphorylation of yeast hexokinase 2 regulates its nucleocytoplasmic shuttling. Fernández-García P, et al. J Biol Chem, 2012 Dec 7. PMID 23066030.
    5. Identification of anaphase promoting complex substrates in S. cerevisiae. Ostapenko D, et al. PLoS One, 2012. PMID 23049888.

    See all (228) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Snf1 interacts with Por1 and Por2.
      Title: Mitochondrial porin Por1 and its homolog Por2 contribute to the positive control of Snf1 protein kinase in Saccharomyces cerevisiae.
    2. we show that under derepressing conditions the recruitment of the histone acetyltransferase Gcn5 is abolished by SNF1 deletion, possibly explaining the lack of increased histone H3 acetylation and nucleosome remodelling.
      Title: Snf1/AMPK regulates Gcn5 occupancy, H3 acetylation and chromatin remodelling at S. cerevisiae ADY2 promoter.
    3. Snf1 is essential for glucose regulation of Hog1 MAPK and Sac1 traffic.
      Title: Metabolic activation of the HOG MAP kinase pathway by Snf1/AMPK regulates lipid signaling at the Golgi.
    4. The IL-1alpha-binding site was mapped to the HAT/Core module of the SAGA complex.
      Title: N-terminal domain of nuclear IL-1α shows structural similarity to the C-terminal domain of Snf1 and binds to the HAT/core module of the SAGA complex.
    5. Snf1 appears to affect multiple steps in gene regulation, including transcription factor binding, RNA polymerase II activity, and cytoplasmic mRNA stability.
      Title: The AMP-activated protein kinase Snf1 regulates transcription factor binding, RNA polymerase II activity, and mRNA stability of glucose-repressed genes in Saccharomyces cerevisiae.
    6. Data show that at the transcription level, Snf1 and inositol-choline interact directly through transcription factors.
      Title: Integrated analysis of transcriptome and lipid profiling reveals the co-influences of inositol-choline and Snf1 in controlling lipid biosynthesis in yeast.
    7. Data show that the Reg1-Glc7 protein phosphatase 1 and Sit4 type 2A-like phosphatase are largely responsible for dephosphorylation of Thr-210 of Snf1(1-309).
      Title: Heterotrimer-independent regulation of activation-loop phosphorylation of Snf1 protein kinase involves two protein phosphatases.
    8. yeast Snf1 participates in metabolic checkpoint control that coordinates growth with nutrient availability.
      Title: Protein kinase A contributes to the negative control of Snf1 protein kinase in Saccharomyces cerevisiae.
    9. the role of Snf1 in tolerance to alkalinization is largely due to the function of the kinase in the adaptation of the cell to glucose scarcity, thus delineating with both the PKA and calcineurin pathways
      Title: The role of the Snf1 kinase in the adaptive response of Saccharomyces cerevisiae to alkaline pH stress.
    10. Snf1 has a role in upregulating the NADP(+)-dependent glutamate dehydrogenase under derepressing condition. direct interactions between Snf1 and TORC1 pathways are unlikely under nutrient-limited conditions.
      Title: Mapping the interaction of Snf1 with TORC1 in Saccharomyces cerevisiae.
    Submit: New GeneRIF Correction See all (52)
    Products Interactant Other Gene Complex Source Pubs Description
    NP_010765.1 NP_010944.1 GAL83    BIND  PubMed Snf1 interacts with Gal83. 
    NP_010765.1 NC_001142.5 INO1    BIND  PubMed Snf1 interacts with Ino1 promoter. 
    NP_010765.1 NP_014163.1 SIN4    BIND  PubMed Snf1 interacts with Sin4. 
    NP_010765.1 NP_010710.1 SIP1    BIND  PubMed Snf1 interacts with Sip1. 
    NP_010765.1 NP_011307.1 SIP2    BIND  PubMed Snf1 interacts with Sip2. 
    NP_010765.1 NP_011400.1 SNF4    BIND  PubMed Snf1 interacts with Snf4 
    NP_010765.1 NP_015283.1 SSN3    BIND  PubMed Snf1 interacts with Srb10. 
    NP_010765.1 NP_014373.1 SSN8    BIND  PubMed Snf1 interacts with Srb11. 
    NP_010765.1 NP_014690.1 STD1    BIND  PubMed Std1 (Msn3) interacts with Snf1. 
    BioGRID:32529 BioGRID:35841 ACC1    BioGRID  PubMed Synthetic Rescue 
    BioGRID:32529 BioGRID:31569 ACO1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31775 ACS1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34317 ADH1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33861 ADO1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32269 ADR1    BioGRID  PubMed Co-localization; Dosage Rescue; Phenotypic Suppression; Synthetic Rescue 
    BioGRID:32529 BioGRID:33177 AFT1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34946 AGE2    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:31092 AGP3    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34427 AHC1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36632 AIM18    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35173 AIM34    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36025 AIM44    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:17518 AKINBETA1    BioGRID  PubMed Two-hybrid 
    BioGRID:32529 BioGRID:33672 ALY2    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:35135 AMD1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32174 APC4    BioGRID  PubMed Two-hybrid 
    BioGRID:32529 BioGRID:34639 APC5    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:32529 BioGRID:31853 ARF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32529 BioGRID:32183 ARO1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36233 ARO7    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33675 ARP4    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:32529 BioGRID:34535 ARP8    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31509 ARV1    BioGRID  PubMed Biochemical Activity; Negative Genetic 
    BioGRID:32529 BioGRID:12624 AT4G16360    BioGRID  PubMed Two-hybrid 
    BioGRID:32529 BioGRID:33074 ATG1    BioGRID  PubMed Dosage Rescue; Negative Genetic; Positive Genetic 
    BioGRID:32529 BioGRID:36357 ATG13    BioGRID  PubMed Dosage Rescue 
    BioGRID:32529 BioGRID:36080 ATG21    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33662 BCK1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31658 BDF1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31990 BDF2    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:36905 BEM2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34596 BFR1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:36930 BMH1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32529 BioGRID:32157 BMH2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32529 BioGRID:36344 BSP1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:36110 BTS1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33440 BUB1    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:31798 BUD14    BioGRID  PubMed Biochemical Activity; Negative Genetic 
    BioGRID:32529 BioGRID:31040 BUD31    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35093 BUL2    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:35041 CAC2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35127 CAT2    BioGRID  PubMed Synthetic Rescue 
    BioGRID:32529 BioGRID:34520 CAT5    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35459 CAT8    BioGRID  PubMed Dosage Rescue 
    BioGRID:32529 BioGRID:32241 CCT6    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:31825 CDC13    BioGRID  PubMed Biochemical Activity; Negative Genetic 
    BioGRID:32529 BioGRID:31182 CDC14    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:32529 BioGRID:35171 CDC5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32529 BioGRID:32969 CHK1    BioGRID  PubMed Negative Genetic; Positive Genetic 
    BioGRID:32529 BioGRID:33405 CHO2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34955 CKA1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36287 CLB2    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:36288 CLB5    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:35377 CLN1    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:31166 CMK1    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:35110 CMP2    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:32529 BioGRID:31276 CMS1    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:31692 CNA1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:32529 BioGRID:33931 CNB1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35611 CNM67    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:32854 CNS1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:35773 COG5    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35783 COG6    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35772 COX5A    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35434 COX7    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34084 CSE4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32529 BioGRID:35222 CSM3    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36625 CTF8    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:33997 CTK1    BioGRID  PubMed Affinity Capture-Western; Negative Genetic; Phenotypic Enhancement; Synthetic Growth Defect; Two-hybrid 
    BioGRID:32529 BioGRID:33750 CTK2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35092 CTK3    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32816 CYC8    BioGRID  PubMed Synthetic Rescue 
    BioGRID:32529 BioGRID:34464 CYT1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:249725 Camkk2    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:33335 DBF2    BioGRID  PubMed Affinity Capture-MS; Positive Genetic 
    BioGRID:32529 BioGRID:30968 DCC1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31753 DEP1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34014 DGR2    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:36476 DOG1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32337 DPP1    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:34202 DRE2    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:33061 DSD1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36868 DSE1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33205 DST1    BioGRID  PubMed Negative Genetic; Reconstituted Complex 
    BioGRID:32529 BioGRID:34315 DUF1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31961 DUN1    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:34085 ELM1    BioGRID  PubMed Negative Genetic; Phenotypic Suppression; Synthetic Growth Defect 
    BioGRID:32529 BioGRID:33453 ELP2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36095 ELP3    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36079 ELP4    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35492 ELP6    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32095 ENA1    BioGRID  PubMed Dosage Rescue; Synthetic Rescue 
    BioGRID:32529 BioGRID:31339 ENV10    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31331 ERG3    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35186 ERG5    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:35161 ERG6    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33940 FAS1    BioGRID  PubMed Synthetic Rescue 
    BioGRID:32529 BioGRID:32742 FAT1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33605 FBP26    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35516 FIG4    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:31604 FKS1    BioGRID  PubMed Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:32529 BioGRID:31661 FLD1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34141 FOX2    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:32682 FUS3    BioGRID  PubMed Positive Genetic; Two-hybrid 
    BioGRID:32529 BioGRID:34894 FYV10    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34573 GAC1    BioGRID  PubMed Dosage Rescue 
    BioGRID:32529 BioGRID:32723 GAL1    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:35915 GAL4    BioGRID  PubMed Negative Genetic; Reconstituted Complex 
    BioGRID:32529 BioGRID:35117 GAL80    BioGRID  PubMed Dosage Growth Defect; Synthetic Rescue 
    BioGRID:32529 BioGRID:36762 GAL83    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Two-hybrid 
    BioGRID:32529 BioGRID:31605 GAS2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32336 GCN2    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:32529 BioGRID:36723 GCN4    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:32529 BioGRID:33503 GCN5    BioGRID  PubMed Biochemical Activity; Reconstituted Complex 
    BioGRID:32529 BioGRID:31779 GEM1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:32529 BioGRID:34600 GEP3    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31364 GEP5    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33226 GET1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:32529 BioGRID:36828 GET2    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:32529 BioGRID:34560 GET4    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32151 GIS1    BioGRID  PubMed Dosage Rescue 
    BioGRID:32529 BioGRID:35584 GIS2    BioGRID  PubMed Dosage Rescue 
    BioGRID:32529 BioGRID:31367 GIS3    BioGRID  PubMed Dosage Rescue 
    BioGRID:32529 BioGRID:35164 GIS4    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Dosage Rescue; Synthetic Growth Defect 
    BioGRID:32529 BioGRID:36877 GLC7    BioGRID  PubMed Affinity Capture-MS; Biochemical Activity 
    BioGRID:32529 BioGRID:36776 GLN3    BioGRID  PubMed Affinity Capture-Western; Biochemical Activity; Two-hybrid 
    BioGRID:32529 BioGRID:36866 GLO3    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:34442 GLO4    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36090 GLR1    BioGRID  PubMed Dosage Rescue 
    BioGRID:32529 BioGRID:33508 GND2    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:34342 GPD2    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:34198 GPT2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35120 GSF2    BioGRID  PubMed Negative Genetic; Reconstituted Complex; Synthetic Growth Defect 
    BioGRID:32529 BioGRID:33653 GSM1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:31526 GSY2    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:32529 BioGRID:33073 GTS1    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:36390 GUT1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34469 GYP1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33714 GYP6    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33646 GZF3    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:35470 HAS1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:33727 HCA4    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:31041 HCM1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:31462 HCR1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:35805 HDA1    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:32529 BioGRID:35473 HER2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35286 HFD1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32711 HHT1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:31384 HOG1    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement 
    BioGRID:32529 BioGRID:34879 HOS4    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:34656 HRK1    BioGRID  PubMed Affinity Capture-MS; Positive Genetic 
    BioGRID:32529 BioGRID:33176 HSF1    BioGRID  PubMed Biochemical Activity; Two-hybrid 
    BioGRID:32529 BioGRID:31132 HSP12    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35923 HSP82    BioGRID  PubMed Synthetic Lethality 
    BioGRID:32529 BioGRID:33476 HSV2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34392 HTZ1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33026 HXK2    BioGRID  PubMed Affinity Capture-Western; Biochemical Activity; Negative Genetic 
    BioGRID:32529 BioGRID:33874 ILM1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35207 IMP2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36478 INM1    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:34293 INO4    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34321 IRA2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36513 IRE1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:32529 BioGRID:31225 ISA1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:33119 ITC1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31947 IWR1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35610 JJJ1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:30931 KAR4    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32067 KCS1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31800 KIN3    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34626 KIN4    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33969 KKQ8    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33287 KSS1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33171 KXD1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34124 LAC1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:34518 LEO1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:32008 LHP1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:34594 LIP5    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:1189563 LOC100353750    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:33939 LOT5    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36516 LRP1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33632 LSM1    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:33962 LST4    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36226 MAK3    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35532 MCK1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34543 MDM32    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34373 MDM38    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33060 MDS3    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:36242 MED1    BioGRID  PubMed Synthetic Rescue 
    BioGRID:32529 BioGRID:32049 MED2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36490 MED6    BioGRID  PubMed PCA 
    BioGRID:32529 BioGRID:34863 MET18    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34337 MET22    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36118 MFM1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35104 MFT1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:33900 MGM101    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35618 MGS1    BioGRID  PubMed Two-hybrid 
    BioGRID:32529 BioGRID:33212 MIG1    BioGRID  PubMed Affinity Capture-Western; Biochemical Activity; Dosage Growth Defect; Synthetic Rescue; Two-hybrid 
    BioGRID:32529 BioGRID:36763 MIG3    BioGRID  PubMed Biochemical Activity; Dosage Growth Defect; Dosage Lethality; Synthetic Rescue 
    BioGRID:32529 BioGRID:34715 MIP1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34624 MKK1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31245 MMM1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31460 MMR1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31584 MMS22    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32296 MNN10    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33579 MNN11    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35402 MRE11    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35998 MRN1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33326 MRP13    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31698 MRPL4    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:34717 MRS2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34123 MRT4    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32255 MSC2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34739 MSC6    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32152 MSH6    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32892 MSI1    BioGRID  PubMed Dosage Rescue 
    BioGRID:32529 BioGRID:34284 MSN1    BioGRID  PubMed Dosage Rescue 
    BioGRID:32529 BioGRID:35209 MSN2    BioGRID  PubMed Biochemical Activity; Dosage Rescue; Negative Genetic; Synthetic Growth Defect 
    BioGRID:32529 BioGRID:34071 MSN4    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:32529 BioGRID:32392 MSN5    BioGRID  PubMed Dosage Rescue 
    BioGRID:32529 BioGRID:34057 MUD2    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:32213 NBP2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31533 NEJ1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:33680 NET1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32529 BioGRID:36009 NIP100    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33967 NNK1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36037 NOP53    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:35649 NPR1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:32529 BioGRID:33290 NQM1    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:32098 NRG1    BioGRID  PubMed Affinity Capture-Western; Synthetic Rescue 
    BioGRID:32529 BioGRID:32769 NRG2    BioGRID  PubMed Affinity Capture-Western; Synthetic Rescue; Two-hybrid 
    BioGRID:32529 BioGRID:36566 NSG1    BioGRID  PubMed Biochemical Activity; Reconstituted Complex 
    BioGRID:32529 BioGRID:34154 NTR2    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:34332 NUF2    BioGRID  PubMed Two-hybrid 
    BioGRID:32529 BioGRID:34213 NUP133    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36341 NUT2    BioGRID  PubMed PCA 
    BioGRID:32529 BioGRID:35765 OCA2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34002 OCT1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32369 OMS1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36403 OPI1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33829 OPI3    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32830 OPY1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36248 OPY2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36507 OSH3    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:34658 PAC1    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:32540 PAC11    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35343 PAH1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:32301 PAM1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34285 PAP2    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:32529 BioGRID:31228 PAU17    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33628 PBS2    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement 
    BioGRID:32529 BioGRID:33344 PCP1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36931 PDA1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34745 PDE2    BioGRID  PubMed Dosage Rescue; Synthetic Growth Defect 
    BioGRID:32529 BioGRID:32694 PDR3    BioGRID  PubMed Two-hybrid 
    BioGRID:32529 BioGRID:32170 PDS1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:36898 PEA2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31461 PEX13    BioGRID  PubMed Two-hybrid 
    BioGRID:32529 BioGRID:35383 PFK2    BioGRID  PubMed Biochemical Activity; Synthetic Rescue 
    BioGRID:32529 BioGRID:34884 PFK26    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:34240 PFK27    BioGRID  PubMed Biochemical Activity; Dosage Growth Defect 
    BioGRID:32529 BioGRID:35080 PGA3    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33222 PGD1    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:32529 BioGRID:31191 PHO4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32529 BioGRID:34403 PHO80    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35082 PHO84    BioGRID  PubMed Synthetic Rescue 
    BioGRID:32529 BioGRID:36147 PHO85    BioGRID  PubMed Synthetic Lethality; Synthetic Rescue 
    BioGRID:32529 BioGRID:35838 PHO91    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:33223 PIB2    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:35945 PLC1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33087 PMR1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34869 POG1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35766 POR1    BioGRID  PubMed Affinity Capture-Western; Negative Genetic; Two-hybrid 
    BioGRID:32529 BioGRID:34877 POR2    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:32529 BioGRID:34832 POT1    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:35445 PPA2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:111507 PPP2CA    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:35153 PPZ1    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:36669 PRB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32529 BioGRID:12566 PRL1    BioGRID  PubMed Two-hybrid 
    BioGRID:32529 BioGRID:32632 PRS4    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35659 PSD1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34357 PSK2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32048 PTC1    BioGRID  PubMed Negative Genetic; Positive Genetic 
    BioGRID:32529 BioGRID:36623 PTH1    BioGRID  PubMed Negative Genetic; Reconstituted Complex 
    BioGRID:32529 BioGRID:33922 PTK1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33816 PTK2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32547 PUF6    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36358 PZF1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:246798 Ppm1a    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:36363 QCR2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36692 RAD23    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:32529 BioGRID:32477 RAD30    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32529 BioGRID:36841 RAD51    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33189 RAD6    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:32529 BioGRID:35725 RAS2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33096 RCK1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32529 BioGRID:31516 RCK2    BioGRID  PubMed Dosage Rescue 
    BioGRID:32529 BioGRID:36048 RDS2    BioGRID  PubMed Biochemical Activity; Reconstituted Complex 
    BioGRID:32529 BioGRID:36591 REC104    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32078 REG1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; PCA; Phenotypic Suppression; Positive Genetic; Synthetic Rescue; Two-hybrid 
    BioGRID:32529 BioGRID:32962 REI1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34308 RFC4    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36282 RGC1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:32191 RGP1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31345 RGR1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:32529 BioGRID:34094 RGT1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34335 RIB2    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:31315 RIC1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31012 RIM1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36395 RIM101    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35316 RIM11    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36398 RIM4    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:35238 RIM9    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35977 RKM1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35236 RNA14    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:32529 BioGRID:33432 RNR4    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:32529 BioGRID:34422 ROD1    BioGRID  PubMed Biochemical Activity; Phenotypic Suppression 
    BioGRID:32529 BioGRID:31175 ROG3    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:32610 ROX3    BioGRID  PubMed Dosage Rescue; Negative Genetic; Synthetic Rescue 
    BioGRID:32529 BioGRID:32208 RPA14    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34724 RPA190    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33610 RPA34    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:34723 RPA43    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:35511 RPD3    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:32529 BioGRID:33584 RPL17B    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36220 RPL43A    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36389 RPL8A    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:34917 RPN2    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:32035 RPN4    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:32529 BioGRID:34363 RPP2A    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34681 RPS10A    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31978 RPS16B    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36408 RPS20    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:36875 RPS26B    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31997 RPS29B    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36637 RPS4B    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34839 RRD1    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:36311 RRP15    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:31047 RSA4    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:36869 RSP5    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:32030 RTK1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:34419 RTS1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32342 RTT103    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31249 RTT109    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34611 RUD3    BioGRID  PubMed Biochemical Activity; Negative Genetic 
    BioGRID:32529 BioGRID:30988 RVS161    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32801 RXT2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33953 SAC1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36873 SAK1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Co-fractionation 
    BioGRID:32529 BioGRID:31198 SAP155    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:35441 SAP30    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36536 SBE22    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:36639 SCH9    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:33676 SCP160    BioGRID  PubMed Biochemical Activity; Reconstituted Complex 
    BioGRID:32529 BioGRID:35451 SCS7    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33928 SDS22    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32529 BioGRID:31439 SEC10    BioGRID  PubMed Dosage Rescue 
    BioGRID:32529 BioGRID:33006 SEC15    BioGRID  PubMed Dosage Rescue 
    BioGRID:32529 BioGRID:35568 SEC2    BioGRID  PubMed Biochemical Activity; Dosage Rescue 
    BioGRID:32529 BioGRID:31536 SEC22    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34916 SEC28    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34644 SEC63    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32221 SEC7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32529 BioGRID:35261 SEG1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32529 BioGRID:32420 SEM1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34162 SET3    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36641 SET5    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:35775 SFB2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34702 SFG1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36368 SGE1    BioGRID  PubMed Dosage Rescue 
    BioGRID:32529 BioGRID:36133 SGF11    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33181 SGF73    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35368 SGS1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32831 SHE3    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:31885 SHS1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:32807 SIF2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34400 SIN3    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35603 SIN4    BioGRID  PubMed Affinity Capture-Western; Negative Genetic; Synthetic Rescue; Two-hybrid 
    BioGRID:32529 BioGRID:32481 SIP1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Dosage Rescue; Negative Genetic; Two-hybrid 
    BioGRID:32529 BioGRID:33048 SIP2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Two-hybrid 
    BioGRID:32529 BioGRID:35582 SIP3    BioGRID  PubMed Two-hybrid 
    BioGRID:32529 BioGRID:33668 SIP4    BioGRID  PubMed Affinity Capture-Western; Two-hybrid 
    BioGRID:32529 BioGRID:35317 SIP5    BioGRID  PubMed Affinity Capture-Western; Two-hybrid 
    BioGRID:32529 BioGRID:35818 SIS1    BioGRID  PubMed Biochemical Activity; Reconstituted Complex 
    BioGRID:32529 BioGRID:32011 SIT4    BioGRID  PubMed Affinity Capture-Western; Phenotypic Suppression; Positive Genetic; Synthetic Rescue 
    BioGRID:32529 BioGRID:36640 SKN7    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32637 SKT5    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:36461 SLT2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36861 SLX8    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33323 SLX9    BioGRID  PubMed Negative Genetic; Positive Genetic 
    BioGRID:32529 BioGRID:33481 SMI1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35109 SML1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:32529 BioGRID:32561 SMT3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32529 BioGRID:34053 SMY1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:32575 SNA2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32529 SNF1    BioGRID  PubMed Affinity Capture-Western; Biochemical Activity; Co-crystal Structure; Reconstituted Complex 
    BioGRID:32529 BioGRID:31851 SNF3    BioGRID  PubMed Dosage Growth Defect 
    BioGRID:32529 BioGRID:33136 SNF4    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-purification; Dosage Rescue; Phenotypic Enhancement; Positive Genetic; Reconstituted Complex; Synthetic Rescue; Two-hybrid 
    BioGRID:32529 BioGRID:22664 SNF4    BioGRID  PubMed Two-hybrid 
    BioGRID:32529 BioGRID:32983 SNF5    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33450 SNG1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31016 SNT1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33124 SOH1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:32529 BioGRID:34164 SPO14    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33049 SPT16    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:34111 SPT23    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32454 SPT3    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31330 SPT8    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32948 SRB6    BioGRID  PubMed PCA 
    BioGRID:32529 BioGRID:31054 SRB8    BioGRID  PubMed Synthetic Rescue 
    BioGRID:32529 BioGRID:31391 SRN2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31786 SSA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32529 BioGRID:31229 SSA2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32529 BioGRID:31882 SSB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32529 BioGRID:35627 SSB2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32529 BioGRID:32345 SSD1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:32365 SSF2    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:35855 SSK2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32498 SSN2    BioGRID  PubMed Dosage Rescue; Synthetic Rescue 
    BioGRID:32529 BioGRID:36137 SSN3    BioGRID  PubMed Affinity Capture-Western; Positive Genetic; Synthetic Rescue; Two-hybrid 
    BioGRID:32529 BioGRID:35801 SSN8    BioGRID  PubMed Affinity Capture-Western; PCA; Positive Genetic; Synthetic Rescue; Two-hybrid 
    BioGRID:32529 BioGRID:34448 STD1    BioGRID  PubMed Reconstituted Complex; Two-hybrid 
    BioGRID:32529 BioGRID:33873 STE24    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:30951 STE50    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34430 STI1    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:31419 STM1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:32517 STP1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33071 STR3    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:36123 SUR1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32349 SUR2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32874 SWD3    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32182 SWF1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36856 SWI4    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31453 SWI6    BioGRID  PubMed Affinity Capture-Western; Negative Genetic 
    BioGRID:32529 BioGRID:35830 SWM2    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:32529 BioGRID:33377 SYF2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34943 SYG1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36002 TCO89    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:32820 TEF2    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:33774 TES1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:36026 TGS1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34385 TLG2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34854 TMA108    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35447 TMA23    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36550 TOM71    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:33823 TOR1    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression 
    BioGRID:32529 BioGRID:33075 TOS3    BioGRID  PubMed Negative Genetic; Positive Genetic 
    BioGRID:32529 BioGRID:31454 TOS4    BioGRID  PubMed Two-hybrid 
    BioGRID:32529 BioGRID:36323 TPO3    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:32827 TPS1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32129 TPS2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36532 TRA1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:32529 BioGRID:33627 TRK1    BioGRID  PubMed Dosage Rescue 
    BioGRID:32529 BioGRID:34181 TRK2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32176 TRM1    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:35081 TUB3    BioGRID  PubMed Dosage Rescue 
    BioGRID:32529 BioGRID:31057 TUP1    BioGRID  PubMed Phenotypic Suppression; Synthetic Rescue 
    BioGRID:32529 BioGRID:32149 UBC13    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31215 UBI4    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:32529 BioGRID:35647 UBP10    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:32633 UBP13    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36901 UBP3    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31160 UBP6    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:34836 UBP7    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:35401 UBP8    BioGRID  PubMed Affinity Capture-Western; Biochemical Activity 
    BioGRID:32529 BioGRID:35156 UBX2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32267 UPC2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31463 UPS1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35037 URA5    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31401 USB1    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:30925 VAC17    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34467 VAM10    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34502 VAM3    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32298 VHS1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34453 VHS3    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:31633 VID22    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35928 VMA11    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33348 VMA21    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:32529 BioGRID:33349 VOA1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:32529 BioGRID:34016 VPH2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34133 VPS1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:34528 VPS17    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33796 VPS55    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35128 VPS71    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:31788 VPS8    BioGRID  PubMed Positive Genetic 
    BioGRID:32529 BioGRID:31601 VRP1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36758 YAT2    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:32644 YBL055C    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:32640 YBL059W    BioGRID  PubMed Dosage Growth Defect 
    BioGRID:32529 BioGRID:32802 YBR096W    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:32529 BioGRID:32981 YBR287W    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36568 YCK1    BioGRID  PubMed Dosage Rescue; Negative Genetic 
    BioGRID:32529 BioGRID:35675 YCK2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36867 YCK3    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35759 YDJ1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31944 YDL119C    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36940 YER186C    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:31093 YFL054C    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:36649 YHR214C-C    BioGRID  PubMed Biochemical Activity; Reconstituted Complex 
    BioGRID:32529 BioGRID:33589 YJL171C    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:33867 YJR111C    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:34108 YKL023W    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:34042 YKL091C    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:34206 YKR075C    BioGRID  PubMed Dosage Growth Defect 
    BioGRID:32529 BioGRID:35464 YKU70    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35132 YMD8    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:36201 YME1    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35278 YMR102C    BioGRID  PubMed Biochemical Activity 
    BioGRID:32529 BioGRID:35344 YMR166C    BioGRID  PubMed Dosage Growth Defect 
    BioGRID:32529 BioGRID:35554 YNL284C-A    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:34418 YOR012W    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35279 YPK2    BioGRID  PubMed Affinity Capture-MS; Negative Genetic 
    BioGRID:32529 BioGRID:36329 YPR158C-C    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32529 BioGRID:31529 YPT6    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:32384 YSP2    BioGRID  PubMed Negative Genetic 
    BioGRID:32529 BioGRID:35264 YTA12    BioGRID  PubMed Negative Genetic 
    • Meiosis - yeast, organism-specific biosystem (from KEGG)
      Meiosis - yeast, organism-specific biosystemDuring meiosis, a single round of DNA replication is followed by two rounds of chromosome segregation, called meiosis I and meiosis II. At meiosis I, one pair of sister chromatids recombines with, th...
    • Meiosis - yeast, conserved biosystem (from KEGG)
      Meiosis - yeast, conserved biosystemDuring meiosis, a single round of DNA replication is followed by two rounds of chromosome segregation, called meiosis I and meiosis II. At meiosis I, one pair of sister chromatids recombines with, th...

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    AMP-activated protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    AMP-activated protein kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    transferase activity, transferring phosphorus-containing groups IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    biofilm formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    cellular response to nitrogen starvation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    invasive growth in response to glucose limitation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    negative regulation of translation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    negative regulation of translation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    positive regulation of filamentous growth of a population of unicellular organisms in response to starvation IMP
    Inferred from Mutant Phenotype
    more info
    		  
    positive regulation of gluconeogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    pseudohyphal growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    regulation of carbohydrate metabolic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    regulation of carbohydrate metabolic process IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    regulation of carbohydrate metabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    replicative cell aging IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    replicative cell aging IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    signal transduction TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    AMP-activated protein kinase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    AMP-activated protein kinase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    cytoplasm IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    fungal-type vacuole IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    nuclear envelope lumen IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    nuclear membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleus IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Names
    Snf1p
    NP_010765.3
    • AMP-activated serine/threonine protein kinase; found in a complex containing Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; involved in regulation of the nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth in response to starvation

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10

      Range
      1412373..1414274
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180785.3 → NP_010765.3  Snf1p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P06782
      Conserved Domains (3) summary
      cd05123
      Location:61 – 306
      Blast Score: 618
      STKc_AGC; Catalytic domain of AGC family Protein Serine/Threonine Kinases
      smart00220
      Location:55 – 306
      Blast Score: 851
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08587
      Location:344 – 389
      Blast Score: 170
      UBA_2; Ubiquitin associated domain (UBA)
    Nucleotide Protein
    Heading Accession and Version
    genomic BK006938.2 DAA12310.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    P06782.1 GenPept

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

      Table of contents

      Related information

      • 3D structures
        3D structure of a gene
      • BioProjects
        BioProjects related to a gene
      • BioSystems
        BioSystems
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • Full text in PMC
        PMC links
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • GEO Profiles
        Related GEO
      • HomoloGene
        Links between HomoloGene and Gene are provided by the HomoloGene group when a gene is included in a HomoloGene record.
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed (GeneRIF)
        GeneRIF -- Gene Reference Into Function Staff of the Index Section in the National Library of Medicine review the current literature. When they find articles focused on the structure and function of a gene, they write a brief summary of the impact of the paper and make the connection between the citation (PubMed) and Gene. An interface exists for interested users to submit such data as well. http://www.ncbi.nlm.nih.gov/projects/GeneRIF/GeneRIFhelp.html
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • Taxonomy
        Link to related taxonomy entry

      Links to other resources

      General information

      Related sites

      Feedback

      Subscription

      Recent activity

      Clear Turn Off Turn On

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...