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SPT3 transcriptional regulator SPT3 [ Saccharomyces cerevisiae S288c ]

Gene ID: 852001, updated on 5-Jul-2015
Gene symbol
SPT3
Gene description
transcriptional regulator SPT3
Primary source
SGD:S000002800
Locus tag
YDR392W
Gene type
protein coding
RNA name
transcriptional regulator SPT3
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See SPT3 in MapViewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1258696..1259709)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene tRNA Neighboring gene hypothetical protein Neighboring gene She9p Neighboring gene proteasome regulatory particle base subunit RPT3

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
transcription cofactor activity IDA
Inferred from Direct Assay
more info
PubMed 
transcription cofactor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
chromatin modification IDA
Inferred from Direct Assay
more info
PubMed 
histone acetylation IDA
Inferred from Direct Assay
more info
PubMed 
invasive growth in response to glucose limitation IDA
Inferred from Direct Assay
more info
PubMed 
pseudohyphal growth IDA
Inferred from Direct Assay
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
SAGA complex IDA
Inferred from Direct Assay
more info
PubMed 
SLIK (SAGA-like) complex IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
transcriptional regulator SPT3
NP_010680.1
  • Subunit of the SAGA and SAGA-like transcriptional regulatory complexes; interacts with Spt15p to activate transcription of some RNA polymerase II-dependent genes, also functions to inhibit transcription at some promoters; relocalizes to the cytosol in response to hypoxia

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1258696..1259709
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180700.1NP_010680.1  transcriptional regulator SPT3 [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_010680.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P06844
    Conserved Domains (1) summary
    cd07978
    Location:495
    TAF13; The TATA Binding Protein (TBP) Associated Factor 13 (TAF13) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex