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    YRA1 Yra1p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 851988, updated on 8-Jan-2012
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    Summary

    Gene symbol
    YRA1
    Gene description
    Yra1p
    Primary source
    SGD:S000002789
    Locus tag
    YDR381W
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    SHE11
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    Genomic context

    Sequence :
    Chromosome: IV; NC_001136.10 (1236558..1238004)
    See YRA1 in MapViewer

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene Aro10p Neighboring gene hypothetical protein Neighboring gene Rpp2bp

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Desumoylation of the endoplasmic reticulum membrane VAP family protein Scs2 by Ulp1 and SUMO regulation of the inositol synthesis pathway. Felberbaum R, et al. Mol Cell Biol, 2012 Jan. PMID 22025676.
    2. The export factor Yra1 modulates mRNA 3' end processing. Johnson SA, et al. Nat Struct Mol Biol, 2011 Sep 25. PMID 21947206.
    3. Assembly of Saccharomyces cerevisiae 60S ribosomal subunits: role of factors required for 27S pre-rRNA processing. Sahasranaman A, et al. EMBO J, 2011 Sep 16. PMID 21926967.
    4. Cotranscriptional association of mRNA export factor Yra1 with C-terminal domain of RNA polymerase II. MacKellar AL, et al. J Biol Chem, 2011 Oct 21. PMID 21856751.
    5. Dynamics of the putative RNA helicase Spb4 during ribosome assembly in Saccharomyces cerevisiae. García-Gómez JJ, et al. Mol Cell Biol, 2011 Oct. PMID 21825077.

    See all (63) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. the phospho-CTD is likely involved directly in the cotranscriptional recruitment of Yra1.
      Title: Cotranscriptional association of mRNA export factor Yra1 with C-terminal domain of RNA polymerase II.
    2. Data indicate that Edc3p-mediated YRA1 pre-mRNA decay occurs independently of translation and also requires Mex67p.
      Title: Degradation of YRA1 Pre-mRNA in the cytoplasm requires translational repression, multiple modular intronic elements, Edc3p, and Mex67p.
    3. Yra1 binds directly to the Zn finger/Clp1 region of Pcf11, the pol II CTD-binding subunit of CF1A.
      Title: Cotranscriptional recruitment of the mRNA export factor Yra1 by direct interaction with the 3' end processing factor Pcf11.
    4. Nap1 interacts directly with Yra1. The recruitment of Nap1 to the coding region of actively transcribed genes is Yra1 dependent.
      Title: Nap1 links transcription elongation, chromatin assembly, and messenger RNP complex biogenesis.
    5. YRA1p can bind to nascent mRNAs, heat shock RNA was exported efficiently in temperature-sensitive YRA1 mutant strains
      Title: Following temperature stress, export of heat shock mRNA occurs efficiently in cells with mutations in genes normally important for mRNA export.
    6. YRA1 exon 1 sequences in cis and Yra1p in trans inhibit YRA1 pre-mRNA splicing and commit the pre-mRNA to nuclear export.
      Title: YRA1 autoregulation requires nuclear export and cytoplasmic Edc3p-mediated degradation of its pre-mRNA.
    7. Dia2 binding to replication origins is significantly reduced when association with Yra1 is compromised
      Title: Yra1 is required for S phase entry and affects Dia2 binding to replication origins.
    8. We propose that appropriate levels of Yra1p are maintained by inefficient cotranscriptional splicing.
      Title: Autoregulation of the mRNA export factor Yra1p requires inefficient splicing of its pre-mRNA.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    NP_010669.1 NP_015156.1 MEX67    BIND  PubMed Yra1 interacts with Mex67. 
    NP_010669.1 NP_010199.1 SUB2    BIND  PubMed Yra1 interacts with Sub2. 
    NP_010669.1     BIND  PubMed Yra1 interacts with the Mex67/Mtr2 complex. 
    BioGRID:32441 BioGRID:32141 AFR1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35958 ALG5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33672 ALY2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35988 APL5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34020 APN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34950 APQ12    BioGRID  PubMed Negative Genetic 
    BioGRID:32441 BioGRID:31442 APS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36440 ARD1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31358 ARP6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34129 AUR1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35415 BCH1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31990 BDF2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35968 BMS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35876 BRE5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35185 BUD22    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36005 CBC2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:32441 BioGRID:31446 CBF5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34947 CBR1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31900 CDC36    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33066 CDC55    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32353 CFT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31387 CFT2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36484 CIC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35315 CIN4    BioGRID  PubMed Two-hybrid 
    BioGRID:32441 BioGRID:34955 CKA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34640 CLP1    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32441 BioGRID:35773 COG5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33785 CPR7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31688 CRN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33997 CTK1    BioGRID  PubMed Far Western; Reconstituted Complex 
    BioGRID:32441 BioGRID:33750 CTK2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35092 CTK3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33088 CUP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35419 CUS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35713 DBP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34447 DBP5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34156 DBP7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34599 DED1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34479 DIA2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Synthetic Lethality 
    BioGRID:32441 BioGRID:32496 DOT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32972 DPB3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35002 DSN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35305 ECM16    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36770 EDC2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36627 EGD2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35608 ELA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33058 EMP24    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31759 ERP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35157 ERV25    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35397 ESC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32422 ESF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35067 FPR3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:30970 GBP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33631 GCD14    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32336 GCN2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32885 GDT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35584 GIS2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-RNA 
    BioGRID:32441 BioGRID:36927 GRX4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33002 HAP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36176 HAT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33727 HCA4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32227 HMO1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32912 HPC2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32192 HPR1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Dosage Growth Defect; Synthetic Lethality; Two-hybrid 
    BioGRID:32441 BioGRID:35821 HRB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34656 HRK1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35980 HRR25    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32699 HTA2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32858 IFA38    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36651 IMD2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35111 IMD4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35976 IPL1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34963 IRR1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31225 ISA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32527 JIP4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36855 KAP123    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33080 KEM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35601 KEX2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35531 KRI1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35972 LEA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33150 LSG1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32672 LSM2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31862 LYS20    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34922 MAM33    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31185 MET10    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36014 MEX67    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Dosage Rescue; Negative Genetic; Reconstituted Complex 
    BioGRID:32441 BioGRID:35104 MFT1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Dosage Growth Defect; Synthetic Lethality 
    BioGRID:32441 BioGRID:34226 MLP1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Synthetic Rescue 
    BioGRID:32441 BioGRID:34843 MLP2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Synthetic Rescue 
    BioGRID:32441 BioGRID:35587 MRPL17    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35654 MRPL22    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32516 MRPL28    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35544 MSB3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36470 MSC7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34367 MSE1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33936 MTR2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33705 MTR4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32821 MUD1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32447 MUS81    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33129 NAB2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-RNA; Affinity Capture-Western; Dosage Rescue; Synthetic Growth Defect; Two-hybrid 
    BioGRID:32441 BioGRID:36521 NAM8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34179 NAP1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Synthetic Growth Defect 
    BioGRID:32441 BioGRID:32018 NAT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32674 NCL1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31150 NIC96    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34601 NOC2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31275 NOC3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34361 NOP12    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35656 NOP13    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35762 NOP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34698 NOP58    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31832 NOP6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34952 NOT3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32489 NPL3    BioGRID  PubMed Affinity Capture-MS; Synthetic Lethality 
    BioGRID:32441 BioGRID:33180 NPY1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32054 NTH1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34496 NUP1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:32441 BioGRID:34876 NUP159    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32624 NUP170    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35040 NUP188    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31599 NUP2    BioGRID  PubMed Synthetic Lethality 
    BioGRID:32441 BioGRID:31790 NUP60    BioGRID  PubMed Affinity Capture-MS; Synthetic Lethality 
    BioGRID:32441 BioGRID:35101 ORC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36335 ORC4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36551 ORC6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32036 OSH2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36918 PAB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34285 PAP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31893 PAR32    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31052 PAT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32927 PBP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33628 PBS2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32280 PCF11    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:32441 BioGRID:36618 PFS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35522 PFS2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35300 PKR1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35036 PML39    BioGRID  PubMed Synthetic Rescue 
    BioGRID:32441 BioGRID:33762 POL31    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:32441 BioGRID:32867 POP7    BioGRID  PubMed Negative Genetic 
    BioGRID:32441 BioGRID:32680 POP8    BioGRID  PubMed Negative Genetic 
    BioGRID:32441 BioGRID:35000 PRI1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34897 PRK1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32016 PRP11    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34217 PRP16    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36745 PRP22    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32294 PRP28    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36350 PRP4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33131 PRP43    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36032 PRP46    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32756 PRP6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33422 PSD2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35488 PSE1    BioGRID  PubMed Affinity Capture-MS; Reconstituted Complex 
    BioGRID:32441 BioGRID:36155 RAD1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36924 RAD3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34449 RAT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36262 RDS3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32247 REF2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33204 RNA15    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:32441 BioGRID:35418 RNT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32610 ROX3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34967 RPB3    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:32441 BioGRID:34212 RPF2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31979 RPL13A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36424 RPL14B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34248 RPL25    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33216 RPL30    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31602 RPP0    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31014 RPS14A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31597 RPS25B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36501 RRP4    BioGRID  PubMed Negative Genetic 
    BioGRID:32441 BioGRID:32333 RRP45    BioGRID  PubMed Affinity Capture-Western; Synthetic Lethality 
    BioGRID:32441 BioGRID:35407 RRP5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34404 RRP6    BioGRID  PubMed Affinity Capture-Western; Synthetic Lethality 
    BioGRID:32441 BioGRID:30952 RRP7    BioGRID  PubMed Negative Genetic 
    BioGRID:32441 BioGRID:34682 RRS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36789 RSM18    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33982 RSM22    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32996 RTF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33027 RTG2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:30988 RVS161    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33953 SAC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32210 SAC3    BioGRID  PubMed Affinity Capture-MS; Synthetic Lethality 
    BioGRID:32441 BioGRID:33659 SAP185    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34608 SAS5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31739 SAW1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36388 SBP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33496 SDA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31296 SDO1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32420 SEM1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:32441 BioGRID:31689 SEN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33591 SET2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35775 SFB2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34992 SGN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32641 SHP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34400 SIN3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31657 SKI2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33043 SKI8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34287 SKM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32566 SLF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36764 SMB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32561 SMT3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33965 SNU114    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36703 SNU13    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31147 SPB4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34168 SPC34    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35159 SPT5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31968 SRP14    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34223 SRP40    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31786 SSA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31229 SSA2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36849 SSA4    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:32441 BioGRID:31882 SSB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35627 SSB2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33797 SSC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36498 SSF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35302 STO1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31977 SUB2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Dosage Growth Defect; Dosage Rescue; Reconstituted Complex 
    BioGRID:32441 BioGRID:36987 SUS1    BioGRID  PubMed Affinity Capture-Western; Synthetic Lethality 
    BioGRID:32441 BioGRID:34114 SWD2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34562 SWT1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:32441 BioGRID:33139 TAF6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34862 TAO3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35586 TEX1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31789 TFC3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36805 THO1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35687 THO2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Synthetic Lethality 
    BioGRID:32441 BioGRID:34329 THP1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:32441 BioGRID:36601 THP2    BioGRID  PubMed Affinity Capture-MS; Dosage Growth Defect; Synthetic Lethality 
    BioGRID:32441 BioGRID:36221 THP3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33414 TIF4631    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33199 TIF4632    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32511 TOM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:35735 TOP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31845 TRM8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31998 TSR1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31693 TSR2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31215 UBI4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36901 UBP3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31160 UBP6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36157 ULP1    BioGRID  PubMed Dosage Rescue; Phenotypic Enhancement; Synthetic Lethality 
    BioGRID:32441 BioGRID:32257 UME6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33792 URB2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33647 UTP10    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32382 UTP4    BioGRID  PubMed Negative Genetic 
    BioGRID:32441 BioGRID:32459 UTP5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32504 UTP6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33376 UTP8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31645 VAC14    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31859 VMA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34659 VPH1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33616 YAK1    BioGRID  PubMed Reconstituted Complex 
    BioGRID:32441 BioGRID:31025 YCR043C    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31996 YDL063C    BioGRID  PubMed Two-hybrid 
    BioGRID:32441 BioGRID:31517 YEF3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36560 YHR127W    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34831 YIL161W    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33839 YJR084W    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34108 YKL023W    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:34056 YKL075C    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31261 YLL054C    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:31714 YLR455W    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36525 YNG2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:32441 YRA1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Two-hybrid 
    BioGRID:32441 BioGRID:33951 YRA2    BioGRID  PubMed Affinity Capture-MS; Dosage Rescue; Synthetic Growth Defect 
    BioGRID:32441 BioGRID:32755 YRO2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:33519 YTA7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32441 BioGRID:36273 YTH1    BioGRID  PubMed Affinity Capture-MS 
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    General gene information

    Homology

    • Homologs of the YRA1 gene: The YRA1 gene is conserved in S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, and N.crassa.

    Pathways from BioSystems

    • RNA transport, organism-specific biosystem (from KEGG)
      RNA transport, organism-specific biosystemRNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) ...
    • RNA transport, conserved biosystem (from KEGG)
      RNA transport, conserved biosystemRNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) ...
    • Spliceosome, organism-specific biosystem (from KEGG)
      Spliceosome, organism-specific biosystemAfter transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, th...
    • Spliceosome, conserved biosystem (from KEGG)
      Spliceosome, conserved biosystemAfter transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, th...
    • mRNA surveillance pathway, organism-specific biosystem (from KEGG)
      mRNA surveillance pathway, organism-specific biosystemThe mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go ...
    • mRNA surveillance pathway, conserved biosystem (from KEGG)
      mRNA surveillance pathway, conserved biosystemThe mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go ...

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    RNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    mRNA export from nucleus IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    regulation of transcription, DNA-dependent IEA
    Inferred from Electronic Annotation
    more info
    		  
    transcription, DNA-dependent IEA
    Inferred from Electronic Annotation
    more info
    		  
    transcription-coupled nucleotide-excision repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    transcription export complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
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    General protein information

    Names
    Yra1p
    NP_010669.1
    • RNA binding protein required for export of poly(A)+ mRNA from the nucleus; proposed to couple mRNA export with 3' end processing via its interactions with Mex67p and Pcf11p; functionally redundant with Yra2p, another REF family member
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10

      Range
      1236558..1238004
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180689.1 → NP_010669.1  Yra1p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q12159
      Conserved Domains (2) summary
      COG0724
      Location:1 – 226
      Blast Score: 82
      COG0724; RNA-binding proteins (RRM domain) [General function prediction only]
      cd00590
      Location:82 – 153
      Blast Score: 146
      RRM; RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA ...
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006938.2 DAA12224.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    Q12159.2 GenPept
    Help top of page

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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