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BCS1 bifunctional AAA family ATPase chaperone/translocase BCS1 [ Saccharomyces cerevisiae S288c ]

Gene ID: 851981, updated on 16-Jul-2016
Gene symbol
BCS1
Gene description
bifunctional AAA family ATPase chaperone/translocase BCS1
Primary source
SGD:S000002783
Locus tag
YDR375C
Gene type
protein coding
RNA name
bifunctional AAA family ATPase chaperone/translocase BCS1
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See BCS1 in Map Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1225166..1226536, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene mRNA-binding phosphate metabolism regulator Neighboring gene Wip1p Neighboring gene NADPH-adrenodoxin reductase Neighboring gene F1F0 ATP synthase subunit f

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATPase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
Names
bifunctional AAA family ATPase chaperone/translocase BCS1
NP_010663.1
  • Protein translocase and chaperone required for Complex III assembly; member of the AAA ATPase family; forms a homo-oligomeric complex in the mitochondrial inner membrane that translocates the C-terminal domain of Rip1p from the matrix across the inner membrane and delivers it to an assembly intermediate of respiratory Complex III; also required for assembly of the Qcr10p subunit; mutation is functionally complemented by human homolog BCS1L, linked to neonatal diseases

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1225166..1226536 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180683.1NP_010663.1  bifunctional AAA family ATPase chaperone/translocase BCS1 [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_010663.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P32839
    Conserved Domains (3) summary
    smart00382
    Location:260390
    AAA; ATPases associated with a variety of cellular activities
    smart01024
    Location:59228
    BCS1_N; This domain is found at the N terminal of the mitochondrial ATPase BSC1. It encodes the import and intramitochondrial sorting for the protein
    pfam00004
    Location:263387
    AAA; ATPase family associated with various cellular activities (AAA)