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ESC2 Esc2p [ Saccharomyces cerevisiae S288c ]

Gene ID: 851965, updated on 5-Apr-2015
Gene symbol
ESC2
Gene description
Esc2p
Primary source
SGD:S000002771
Locus tag
YDR363W
Gene type
protein coding
RNA name
Esc2p
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See ESC2 in MapViewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1199183..1200553)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Bcp1p Neighboring gene transcription factor TFIIIC subunit TFC6 Neighboring gene tRNA Neighboring gene proteasome regulatory particle lid subunit SEM1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by GO

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
chromatin silencing at silent mating-type cassette IMP
Inferred from Mutant Phenotype
more info
PubMed 
double-strand break repair via homologous recombination IGI
Inferred from Genetic Interaction
more info
PubMed 
double-strand break repair via homologous recombination IMP
Inferred from Mutant Phenotype
more info
PubMed 
intra-S DNA damage checkpoint IGI
Inferred from Genetic Interaction
more info
PubMed 
intra-S DNA damage checkpoint IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic sister chromatid cohesion IGI
Inferred from Genetic Interaction
more info
PubMed 
mitotic sister chromatid cohesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of protein sumoylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
Esc2p
NP_010650.1
  • Sumo-like domain protein; prevents accumulation of toxic intermediates during replication-associated recombinational repair; roles in silencing, lifespan, chromatid cohesion and the intra-S-phase DNA damage checkpoint; RENi family member

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1199183..1200553
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180671.1NP_010650.1  Esc2p [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_010650.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q06340
    Conserved Domains (2) summary
    pfam11976
    Location:384455
    Rad60-SLD; Ubiquitin-2 like Rad60 SUMO-like
    cl21478
    Location:265357
    Mt_ATP-synt_B; Mitochondrial ATP synthase B chain precursor (ATP-synt_B)