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    YDR248C hypothetical protein [ Saccharomyces cerevisiae S288c ]

    Gene ID: 851835, updated on 8-Jan-2012
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    Summary

    Gene symbol
    YDR248C
    Gene description
    hypothetical protein
    Primary source
    SGD:S000002656
    Locus tag
    YDR248C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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    Genomic context

    Sequence :
    Chromosome: IV; NC_001136.10 (957758..958339, complement)
    See YDR248C in MapViewer

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene Vhs1p Neighboring gene hypothetical protein Neighboring gene Pam1p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. The genetic landscape of a cell. Costanzo M, et al. Science, 2010 Jan 22. PMID 20093466.
    2. Purification of nuclear poly(A)-binding protein Nab2 reveals association with the yeast transcriptome and a messenger ribonucleoprotein core structure. Batisse J, et al. J Biol Chem, 2009 Dec 11. PMID 19840948.
    3. Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Krogan NJ, et al. Nature, 2006 Mar 30. PMID 16554755.
    4. An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae. Lesage G, et al. BMC Genet, 2005 Feb 16. PMID 15715908.
    5. Global mapping of the yeast genetic interaction network. Tong AH, et al. Science, 2004 Feb 6. PMID 14764870.

    See all (8) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:32299 BioGRID:35580 ATX1    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:36749 BIM1    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:32607 BNA4    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:34167 CAF4    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:35641 CHS1    BioGRID  PubMed Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:32299 BioGRID:32356 CPR5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:32299 BioGRID:35852 CPR8    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:36142 EGD1    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:33453 ELP2    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:33305 ERG25    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:36084 ERI1    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:31105 FET5    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:31482 FRE1    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:35487 GAS1    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:33325 GCD2    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:31119 GYP8    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:36331 KRE6    BioGRID  PubMed Synthetic Lethality 
    BioGRID:32299 BioGRID:32902 KTR3    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:31697 LSM3    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:33196 MST27    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:33129 NAB2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:32299 BioGRID:35040 NUP188    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:34616 ODC2    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:32764 ORC2    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:34393 PLB3    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:31927 PPH21    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:33334 PRP31    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:36350 PRP4    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:36510 PTC7    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:33204 RNA15    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:31979 RPL13A    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:36469 RRF1    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:35451 SCS7    BioGRID  PubMed Positive Genetic 
    BioGRID:32299 BioGRID:32911 SDS24    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:33885 STR2    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:36987 SUS1    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:31755 SWC3    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:32895 TAF5    BioGRID  PubMed Positive Genetic 
    BioGRID:32299 BioGRID:35090 TAF8    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:33445 TDH3    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:36601 THP2    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:32761 UBP14    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:31298 UBR2    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:36678 VMA8    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:35636 WHI3    BioGRID  PubMed Positive Genetic 
    BioGRID:32299 BioGRID:31363 XDJ1    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:32841 YBR141C    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:31562 YHC1    BioGRID  PubMed Positive Genetic 
    BioGRID:32299 BioGRID:34150 YKR018C    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:31421 YLR152C    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:31565 YLR301W    BioGRID  PubMed Negative Genetic 
    BioGRID:32299 BioGRID:34621 YOR228C    BioGRID  PubMed Negative Genetic 
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    General gene information

    Homology

    • Homologs of the YDR248C gene: The YDR248C gene is conserved in human, chimpanzee, dog, mouse, rat, chicken, C.elegans, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, and A.thaliana.

    Pathways from BioSystems

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    gluconokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    molecular_function ND
    No biological Data available
    more info
    		  
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    transferase activity, transferring phosphorus-containing groups IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    D-gluconate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    biological_process ND
    No biological Data available
    more info
    		  
    carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    sulfate assimilation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Names
    hypothetical protein
    NP_010534.1
    • hypothetical protein; sequence similarity to bacterial and human gluconokinase; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; upregulated by deletion of the RNAP-II associated factor, PAF1
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10

      Range
      957758..958339, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180556.1 → NP_010534.1  hypothetical protein YDR248C [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q03786
      Conserved Domains (2) summary
      cd02021
      Location:13 – 171
      Blast Score: 471
      GntK; Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.
      COG3265
      Location:18 – 189
      Blast Score: 508
      GntK; Gluconate kinase [Carbohydrate transport and metabolism]
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006938.2 DAA12089.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    Q03786.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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