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MSC2 metal cation transporter MSC2 [ Saccharomyces cerevisiae S288c ]

Gene ID: 851786, updated on 16-Jan-2015
Gene symbol
MSC2
Gene description
metal cation transporter MSC2
Primary source
SGD:S000002613
Locus tag
YDR205W
Gene type
protein coding
RNA name
metal cation transporter MSC2
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See MSC2 in MapViewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (859346..861520)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Rav2p Neighboring gene Coq4p Neighboring gene Ebs1p Neighboring gene Ume6p

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
cation transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
zinc ion transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
cation transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
cation transport IEA
Inferred from Electronic Annotation
more info
 
cellular zinc ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
ion transport IEA
Inferred from Electronic Annotation
more info
 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
transmembrane transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
transport IEA
Inferred from Electronic Annotation
more info
 
zinc ion transport IEA
Inferred from Electronic Annotation
more info
 
zinc ion transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane ISM
Inferred from Sequence Model
more info
PubMed 
integral component of membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
nuclear membrane IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
metal cation transporter MSC2
NP_010491.4
  • Endoplasmic reticulum zinc transporter; part of a heterodimeric transporter with Zrg17p that transfers zinc from the cytosol to the ER lumen; member of the cation diffusion facilitator family of efflux pumps; localizes to ER and nucleus; mutations affect the cellular distribution of zinc and also confer defects in meiotic recombination between homologous chromatids

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 

    Range
    859346..861520
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180513.3NP_010491.4  metal cation transporter MSC2 [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_010491.4

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q03455
    Conserved Domains (1) summary
    COG1230
    Location:378673
    CzcD; Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]