Format

Send to:

Choose Destination

LYS20 homocitrate synthase LYS20 [ Saccharomyces cerevisiae S288c ]

Gene ID: 851346, updated on 7-Feb-2016
Gene symbol
LYS20
Gene description
homocitrate synthase LYS20
Primary source
SGD:S000002341
Locus tag
YDL182W
Gene type
protein coding
RNA name
homocitrate synthase LYS20
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See LYS20 in MapViewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (133437..134723)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene ribosomal 60S subunit protein L41A Neighboring gene hypothetical protein Neighboring gene Inh1p Neighboring gene hypothetical protein

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
homocitrate synthase activity IDA
Inferred from Direct Assay
more info
PubMed 
homocitrate synthase activity IEA
Inferred from Electronic Annotation
more info
 
homocitrate synthase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
DNA repair IGI
Inferred from Genetic Interaction
more info
PubMed 
carboxylic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
cellular amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
histone displacement IGI
Inferred from Genetic Interaction
more info
PubMed 
lysine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
lysine biosynthetic process via aminoadipic acid IEA
Inferred from Electronic Annotation
more info
 
lysine biosynthetic process via aminoadipic acid IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Names
homocitrate synthase LYS20
NP_010099.1
  • Homocitrate synthase isozyme and functions in DNA repair; catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; LYS20 has a paralog, LYS21, that arose from the whole genome duplication

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    133437..134723
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180242.1NP_010099.1  homocitrate synthase LYS20 [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_010099.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P48570
    Conserved Domains (2) summary
    TIGR02146
    Location:25371
    LysS_fung_arch; homocitrate synthase
    cd07948
    Location:23284
    DRE_TIM_HCS; Saccharomyces cerevisiae homocitrate synthase and related proteins, catalytic TIM barrel domain