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GCV3 glycine decarboxylase subunit H [ Saccharomyces cerevisiae S288c ]

Gene ID: 851254, updated on 15-Jan-2015
Gene symbol
GCV3
Gene description
glycine decarboxylase subunit H
Primary source
SGD:S000000042
Locus tag
YAL044C
Gene type
protein coding
RNA name
glycine decarboxylase subunit H
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See GCV3 in MapViewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_001133.9 (57950..58462, complement)

Chromosome I - NC_001133.9Genomic Context describing neighboring genes Neighboring gene Aim1p Neighboring gene hypothetical protein Neighboring gene Pta1p Neighboring gene Erv46p

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
contributes_to glycine dehydrogenase (decarboxylating) activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
glycine catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
glycine decarboxylation via glycine cleavage system IEA
Inferred from Electronic Annotation
more info
 
one-carbon metabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
protein lipoylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
glycine cleavage complex IEA
Inferred from Electronic Annotation
more info
 
glycine cleavage complex ISA
Inferred from Sequence Alignment
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
Names
glycine decarboxylase subunit H
NP_009355.3
  • H subunit of the mitochondrial glycine decarboxylase complex; glycine decarboxylase is required for the catabolism of glycine to 5,10-methylene-THF; also required for all protein lipoylation; expression is regulated by levels of 5,10-methylene-THF

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001133.9 

    Range
    57950..58462
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178189.1NP_009355.3  glycine decarboxylase subunit H [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_009355.3

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P39726
    Conserved Domains (1) summary
    cd06848
    Location:47142
    GCS_H; Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and ...