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    ARC18 Arc18p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 851085, updated on 21-Jan-2012

    Summary

    Gene symbol
    ARC18
    Gene description
    Arc18p
    Primary source
    SGD:S000004362
    Locus tag
    YLR370C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces

    Genomic context

    Sequence :
    Chromosome: XII; NC_001144.5 (861718..862254, complement)
    See ARC18 in MapViewer

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Mdm30p Neighboring gene Ssq1p Neighboring gene Rom2p Neighboring gene Sur4p

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:31630 BioGRID:35247 ABF2    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:31060 ABP1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:31569 ACO1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:31107 ACT1    BioGRID  PubMed Synthetic Haploinsufficiency 
    BioGRID:31630 BioGRID:36025 AIM44    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:34405 ALG6    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:31630 BioGRID:34466 ALG8    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:31630 BioGRID:35055 ALO1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:34930 ARC15    BioGRID  PubMed Affinity Capture-MS; Co-purification; FRET 
    BioGRID:31630 BioGRID:31630 ARC18    BioGRID  PubMed PCA 
    BioGRID:31630 BioGRID:34119 ARC19    BioGRID  PubMed Affinity Capture-MS; Co-purification; PCA 
    BioGRID:31630 BioGRID:35861 ARC35    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Co-purification 
    BioGRID:31630 BioGRID:32929 ARC40    BioGRID  PubMed Affinity Capture-MS; PCA; Synthetic Lethality 
    BioGRID:31630 BioGRID:36440 ARD1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31630 BioGRID:31853 ARF1    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:31630 BioGRID:36562 ARP1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:32027 ARP2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Co-purification; PCA; Synthetic Lethality 
    BioGRID:31630 BioGRID:33822 ARP3    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Co-purification 
    BioGRID:31630 BioGRID:33675 ARP4    BioGRID  PubMed Synthetic Lethality 
    BioGRID:31630 BioGRID:35292 ASC1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:33639 ASF1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:31630 BioGRID:36357 ATG13    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:33662 BCK1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:32897 BEM1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:36066 BEM3    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:36022 BEM4    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:34833 BNR1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:31987 BRE1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31630 BioGRID:35876 BRE5    BioGRID  PubMed Positive Genetic 
    BioGRID:31630 BioGRID:34125 CAP1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:34956 CAP2    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:33470 CCH1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:31383 CCW12    BioGRID  PubMed Phenotypic Suppression; Synthetic Lethality 
    BioGRID:31630 BioGRID:31825 CDC13    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31630 BioGRID:33135 CDC20    BioGRID  PubMed Synthetic Lethality 
    BioGRID:31630 BioGRID:33050 CHC1    BioGRID  PubMed PCA 
    BioGRID:31630 BioGRID:35641 CHS1    BioGRID  PubMed Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:31630 BioGRID:32726 CHS3    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:31630 BioGRID:31594 CHS5    BioGRID  PubMed Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:31630 BioGRID:33658 CHS6    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:31630 BioGRID:36575 CHS7    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:35540 CLA4    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:34387 CMK2    BioGRID  PubMed Reconstituted Complex 
    BioGRID:31630 BioGRID:31360 CSF1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:32737 CSG2    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:36001 CTI6    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:33801 CYC1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:31148 DEG1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:35479 DYN3    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:32780 ECM33    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:34541 ELG1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31630 BioGRID:36095 ELP3    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31630 BioGRID:33842 EMC2    BioGRID  PubMed Positive Genetic 
    BioGRID:31630 BioGRID:33193 ERV14    BioGRID  PubMed Negative Genetic; Phenotypic Suppression 
    BioGRID:31630 BioGRID:34635 ESA1    BioGRID  PubMed Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:31630 BioGRID:31172 FAB1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:35755 FKH2    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:31270 FPS1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:31747 FUN30    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:31630 BioGRID:34600 GEP3    BioGRID  PubMed Positive Genetic 
    BioGRID:31630 BioGRID:33226 GET1    BioGRID  PubMed Positive Genetic; Synthetic Lethality 
    BioGRID:31630 BioGRID:36828 GET2    BioGRID  PubMed Phenotypic Suppression; Synthetic Lethality 
    BioGRID:31630 BioGRID:35676 GIM3    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:36728 GIM4    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:35805 HDA1    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:31630 BioGRID:32347 HDA2    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31630 BioGRID:36351 HDA3    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:31630 BioGRID:35473 HER2    BioGRID  PubMed Positive Genetic 
    BioGRID:31630 BioGRID:35338 HLJ1    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:31630 BioGRID:35204 HOF1    BioGRID  PubMed Positive Genetic 
    BioGRID:31630 BioGRID:35923 HSP82    BioGRID  PubMed Synthetic Lethality 
    BioGRID:31630 BioGRID:34902 ICE2    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:33874 ILM1    BioGRID  PubMed Negative Genetic; Phenotypic Suppression 
    BioGRID:31630 BioGRID:32368 IPK1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:35474 JNM1    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:31630 BioGRID:33845 JSN1    BioGRID  PubMed Co-localization; Negative Genetic 
    BioGRID:31630 BioGRID:33726 KAR2    BioGRID  PubMed Positive Genetic 
    BioGRID:31630 BioGRID:33080 KEM1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:34576 LAS17    BioGRID  PubMed Affinity Capture-MS; PCA 
    BioGRID:31630 BioGRID:33692 LAS21    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:31266 LDB18    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:35517 LEM3    BioGRID  PubMed Phenotypic Suppression; Positive Genetic 
    BioGRID:31630 BioGRID:36125 LGE1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:31630 BioGRID:33632 LSM1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:32437 LSM6    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:31742 LTE1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:31630 BioGRID:33729 MAD2    BioGRID  PubMed Synthetic Lethality 
    BioGRID:31630 BioGRID:34543 MDM32    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:34715 MIP1    BioGRID  PubMed Positive Genetic 
    BioGRID:31630 BioGRID:31460 MMR1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:35402 MRE11    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:35874 MSO1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:35285 MYO5    BioGRID  PubMed Affinity Capture-Western; Negative Genetic; PCA 
    BioGRID:31630 BioGRID:33129 NAB2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:31630 BioGRID:34179 NAP1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:32018 NAT1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31630 BioGRID:36009 NIP100    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:32203 NUM1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:34658 PAC1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:34285 PAP2    BioGRID  PubMed Synthetic Lethality 
    BioGRID:31630 BioGRID:31052 PAT1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:31468 PBA1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:33430 PBP1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:30941 PDI1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:31630 BioGRID:31026 PER1    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:31630 BioGRID:34401 PFA4    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:33582 PFD1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:31630 BioGRID:33492 PFK1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31630 BioGRID:35080 PGA3    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:35726 PHO23    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:31630 BioGRID:34403 PHO80    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:31630 BioGRID:35300 PKR1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:33087 PMR1    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:31630 BioGRID:31743 PMT2    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:31630 BioGRID:33794 POL32    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31630 BioGRID:35445 PPA2    BioGRID  PubMed Positive Genetic 
    BioGRID:31630 BioGRID:34897 PRK1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:34953 PRM2    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:34746 PRT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31630 BioGRID:31053 PTC6    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:33232 PUF4    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:31042 RAD18    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31630 BioGRID:34021 RAD27    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:33189 RAD6    BioGRID  PubMed Synthetic Lethality 
    BioGRID:31630 BioGRID:32956 RGD1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:34664 RIM20    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:36092 RLM1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:35511 RPD3    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31630 BioGRID:36458 RPN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31630 BioGRID:31249 RTT109    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31630 BioGRID:34611 RUD3    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:32449 RVS167    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:32801 RXT2    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:35441 SAP30    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:31630 BioGRID:33115 SEC27    BioGRID  PubMed PCA 
    BioGRID:31630 BioGRID:34644 SEC63    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:34162 SET3    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:31630 BioGRID:34437 SHE4    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:34400 SIN3    BioGRID  PubMed Synthetic Lethality 
    BioGRID:31630 BioGRID:32637 SKT5    BioGRID  PubMed Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:31630 BioGRID:35394 SKY1    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:31630 BioGRID:35596 SLA2    BioGRID  PubMed PCA 
    BioGRID:31630 BioGRID:36461 SLT2    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:36861 SLX8    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31630 BioGRID:34712 SNC2    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:36698 SPF1    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:31630 BioGRID:33308 SPT4    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:31630 BioGRID:35688 SRV2    BioGRID  PubMed PCA 
    BioGRID:31630 BioGRID:31048 SSK22    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:33873 STE24    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:33575 SWE1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:32182 SWF1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:36856 SWI4    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:36263 SYT1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:32266 TCP1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:31630 BioGRID:34385 TLG2    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:35141 TSA1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31630 BioGRID:31215 UBI4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31630 BioGRID:36043 UME1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:34174 UTH1    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:31859 VMA1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:31630 BioGRID:35928 VMA11    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:34016 VPH2    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:34133 VPS1    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:31630 BioGRID:35046 VPS9    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:31630 BioGRID:36806 YER064C    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31630 BioGRID:36874 YER130C    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:32998 YGL242C    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:33368 YGR122W    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:36201 YME1    BioGRID  PubMed Positive Genetic 
    BioGRID:31630 BioGRID:35249 YMR074C    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:36113 YPL066W    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:36259 YPR089W    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:36766 YPT31    BioGRID  PubMed Negative Genetic 
    BioGRID:31630 BioGRID:31529 YPT6    BioGRID  PubMed Positive Genetic 
    BioGRID:31630 BioGRID:35264 YTA12    BioGRID  PubMed Positive Genetic 

    General gene information

    Homology

    • Homologs of the ARC18 gene: The ARC18 gene is conserved in human, chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.pombe, S.cerevisiae, K.lactis, M.grisea, N.crassa, A.thaliana, and rice.

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    actin filament organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    establishment of mitochondrion localization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitochondrion inheritance TAS
    Traceable Author Statement
    more info
    PubMed 
    regulation of actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    Arp2/3 protein complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Names
    Arc18p
    NP_013474.1
    • Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5

      Range
      861718..862254, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182259.1NP_013474.1  Arc18p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q05933
      Conserved Domains (1) summary
      pfam04062
      Location:1178
      Blast Score: 813
      P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006945.2 DAA09673.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    Q05933.1 GenPept

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