Format

Send to:

Choose Destination

ACO1 aconitate hydratase ACO1 [ Saccharomyces cerevisiae S288c ]

Gene ID: 851013, updated on 5-Jun-2016
Gene symbol
ACO1
Gene description
aconitate hydratase ACO1
Primary source
SGD:S000004295
Locus tag
YLR304C
Gene type
protein coding
RNA name
aconitate hydratase ACO1
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
GLU1
See ACO1 in Map Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (735212..737548, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene bifunctional cysteine synthase/O-acetylhomoserine aminocarboxypropyltransferase MET17 Neighboring gene tRNA Neighboring gene 1-phosphatidylinositol 4-kinase STT4 Neighboring gene NEDD8-conjugating protein UBC12

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
aconitate hydratase activity IDA
Inferred from Direct Assay
more info
PubMed 
aconitate hydratase activity IEA
Inferred from Electronic Annotation
more info
 
aconitate hydratase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
double-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
lyase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
single-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
metabolic process IEA
Inferred from Electronic Annotation
more info
 
mitochondrial genome maintenance IMP
Inferred from Mutant Phenotype
more info
PubMed 
tricarboxylic acid cycle IDA
Inferred from Direct Assay
more info
PubMed 
tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial matrix IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial nucleoid IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
Names
aconitate hydratase ACO1
NP_013407.1
  • Aconitase; required for the tricarboxylic acid (TCA) cycle and also independently required for mitochondrial genome maintenance; component of the mitochondrial nucleoid; mutation leads to glutamate auxotrophy; human homolog ACO2 can complement yeast null mutant

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    735212..737548 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182192.1NP_013407.1  aconitate hydratase ACO1 [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_013407.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P19414
    Conserved Domains (3) summary
    cd01584
    Location:91502
    AcnA_Mitochondrial; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle
    cd01578
    Location:584732
    AcnA_Mitochon_Swivel; Mitochondrial aconitase A swivel domain. Aconitase (also known as aconitate hydratase and citrate hydro-lyase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes ...
    TIGR01340
    Location:41772
    aconitase_mito; aconitate hydratase, mitochondrial