My NCBISign In

Display Settings:

Format

Send to:

Choose Destination

    YEF3 Yef3p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 850951, updated on 4-Feb-2012
    Help top of page

    Summary

    Gene symbol
    YEF3
    Gene description
    Yef3p
    Primary source
    SGD:S000004239
    Locus tag
    YLR249W
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    TEF3
    Help top of page

    Genomic context

    Sequence :
    Chromosome: XII; NC_001144.5 (636780..639914)
    See YEF3 in MapViewer

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Irc20p Neighboring gene Rck2p Neighboring gene Ssp120p Neighboring gene Sym1p

    Help top of page

    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
    Helptop of page

    Bibliography

    Related articles in PubMed

    1. Sites of ubiquitin attachment in Saccharomyces cerevisiae. Starita LM, et al. Proteomics, 2012 Jan. PMID 22106047.
    2. A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. Hoppins S, et al. J Cell Biol, 2011 Oct 17. PMID 21987634.
    3. Assembly of Saccharomyces cerevisiae 60S ribosomal subunits: role of factors required for 27S pre-rRNA processing. Sahasranaman A, et al. EMBO J, 2011 Sep 16. PMID 21926967.
    4. Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes. Lee KK, et al. Mol Syst Biol, 2011 Jul 5. PMID 21734642.
    5. Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell. Magtanong L, et al. Nat Biotechnol, 2011 May 15. PMID 21572441.

    See all (42) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
    Help top of page

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:31517 BioGRID:31422 ACS2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:34317 ADH1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36352 AOS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:34639 APC5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36771 ARB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:32027 ARP2    BioGRID  PubMed Synthetic Lethality 
    BioGRID:31517 BioGRID:35763 ARP5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:35876 BRE5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36132 CAM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:34956 CAP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:33832 CDC11    BioGRID  PubMed Dosage Rescue 
    BioGRID:31517 BioGRID:34109 CDC16    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:33066 CDC55    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:31676 CDC73    BioGRID  PubMed Protein-RNA 
    BioGRID:31517 BioGRID:35783 COG6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:34084 CSE4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:34272 CTR9    BioGRID  PubMed Protein-RNA 
    BioGRID:31517 BioGRID:36603 DBP8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:35947 DIM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:35002 DSN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36392 ECM29    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:31787 EFB1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Two-hybrid 
    BioGRID:31517 BioGRID:34529 EFT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:32446 EFT2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36235 FCY1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:35584 GIS2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-RNA 
    BioGRID:31517 BioGRID:33028 HFM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:35204 HOF1    BioGRID  PubMed Positive Genetic 
    BioGRID:31517 BioGRID:34391 HRD1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:34656 HRK1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:35364 HSC82    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:31226 HSP104    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:31133 IES1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36517 KSP1    BioGRID  PubMed Biochemical Activity 
    BioGRID:31517 BioGRID:34518 LEO1    BioGRID  PubMed Protein-RNA 
    BioGRID:31517 BioGRID:33632 LSM1    BioGRID  PubMed Negative Genetic 
    BioGRID:31517 BioGRID:32285 LYS4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:35532 MCK1    BioGRID  PubMed Biochemical Activity 
    BioGRID:31517 BioGRID:31245 MMM1    BioGRID  PubMed Positive Genetic 
    BioGRID:31517 BioGRID:33830 MOG1    BioGRID  PubMed Positive Genetic 
    BioGRID:31517 BioGRID:36099 MOT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:34123 MRT4    BioGRID  PubMed Positive Genetic 
    BioGRID:31517 BioGRID:31737 MYO4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:33129 NAB2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:31517 BioGRID:36521 NAM8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:35138 NDC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:35959 NEW1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36604 NMD3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:34876 NUP159    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:33718 NUP192    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:32973 PAF1    BioGRID  PubMed Protein-RNA 
    BioGRID:31517 BioGRID:31052 PAT1    BioGRID  PubMed Negative Genetic 
    BioGRID:31517 BioGRID:31468 PBA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:32927 PBP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:31319 PDC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:32893 PGI1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:35097 POB3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:31292 POM34    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:35633 PSY2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:35589 RAD50    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36841 RAD51    BioGRID  PubMed Positive Genetic 
    BioGRID:31517 BioGRID:35137 RAD52    BioGRID  PubMed Positive Genetic 
    BioGRID:31517 BioGRID:31315 RIC1    BioGRID  PubMed Positive Genetic 
    BioGRID:31517 BioGRID:34967 RPB3    BioGRID  PubMed Protein-RNA 
    BioGRID:31517 BioGRID:34212 RPF2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36050 RPL5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36458 RPN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36634 RPN10    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:31152 RPN11    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:34513 RPT5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:32143 RRP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:32996 RTF1    BioGRID  PubMed Protein-RNA 
    BioGRID:31517 BioGRID:33659 SAP185    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:33235 SCL1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:35038 SEC65    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:33181 SGF73    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:34005 SHE2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:31517 BioGRID:32017 SIR2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:31404 SLX4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:32561 SMT3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36897 SPT15    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:32783 SPT7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:32869 SSE2    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:31517 BioGRID:36498 SSF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36496 SSZ1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:32220 STB3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:31419 STM1    BioGRID  PubMed Dosage Growth Defect 
    BioGRID:31517 BioGRID:32225 SUP35    BioGRID  PubMed Dosage Rescue 
    BioGRID:31517 BioGRID:32843 SUP45    BioGRID  PubMed Dosage Rescue 
    BioGRID:31517 BioGRID:33377 SYF2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:34484 TCB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36251 TEF1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:31517 BioGRID:32820 TEF2    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:31517 BioGRID:34051 TEF4    BioGRID  PubMed Affinity Capture-MS; Phenotypic Enhancement 
    BioGRID:31517 BioGRID:34480 TGL5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:33619 TIF2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:33414 TIF4631    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:34489 TMA46    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:32511 TOM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36788 TPA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:31215 UBI4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36901 UBP3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:35401 UBP8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:34118 URB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36346 VPS4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:35163 YAP1    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:31517 BioGRID:36706 YEL023C    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36409 YLF2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:31346 YLR072W    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:36201 YME1    BioGRID  PubMed Positive Genetic 
    BioGRID:31517 BioGRID:34146 YPT52    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:31529 YPT6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31517 BioGRID:32441 YRA1    BioGRID  PubMed Affinity Capture-MS 
    Help top of page

    General gene information

    Homology

    • Homologs of the YEF3 gene: The YEF3 gene is conserved in S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, and N.crassa.

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    ATPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    ATPase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleoside-triphosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    translation elongation factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    translation elongation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    ATP catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    translational elongation IEA
    Inferred from Electronic Annotation
    more info
    		  
    translational elongation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    translational elongation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    translational termination IDA
    Inferred from Direct Assay
    more info
    		  
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    cytosolic ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Help top of page

    General protein information

    Names
    Yef3p
    NP_013350.1
    • Gamma subunit of translational elongation factor eEF1B, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes by releasing eEF1A (Tef1p/Tef2p) from the ribosomal complex; contains two ABC cassettes; binds and hydrolyzes ATP
    Help top of page

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5

      Range
      636780..639914
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182136.1 → NP_013350.1  Yef3p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P16521
      Conserved Domains (2) summary
      COG0488
      Location:429 – 986
      Blast Score: 862
      Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]
      cd03221
      Location:431 – 617
      Blast Score: 350
      ABCF_EF-3; ABCF_EF-3 Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated ...
    Help top of page

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006945.2 DAA09563.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    P16521.4 GenPept
    Help top of page

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

      Supplemental Content

      Recent activity

      Clear Turn Off Turn On

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...