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    UPS1 Ups1p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 850890, updated on 31-Jan-2012
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    Summary

    Gene symbol
    UPS1
    Gene description
    Ups1p
    Primary source
    SGD:S000004183
    Locus tag
    YLR193C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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    Genomic context

    Sequence :
    Chromosome: XII; NC_001144.5 (540009..540536, complement)
    See UPS1 in MapViewer

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Pex13p Neighboring gene Hcr1p Neighboring gene hypothetical protein Neighboring gene Nmt1p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. Hoppins S, et al. J Cell Biol, 2011 Oct 17. PMID 21987634.
    2. Distinct functions of evolutionary conserved MSF1 and late embryogenesis abundant (LEA)-like domains in mitochondria. Hall BM, et al. J Biol Chem, 2011 Nov 11. PMID 21930701.
    3. Absence of mitochondrial translation control proteins extends life span by activating sirtuin-dependent silencing. Caballero A, et al. Mol Cell, 2011 May 6. PMID 21549315.
    4. Regulation of mitochondrial phospholipids by Ups1/PRELI-like proteins depends on proteolysis and Mdm35. Potting C, et al. EMBO J, 2010 Sep 1. PMID 20657548.
    5. Mdm35p imports Ups proteins into the mitochondrial intermembrane space by functional complex formation. Tamura Y, et al. EMBO J, 2010 Sep 1. PMID 20622808.

    See all (15) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. The authors show that Ups1, Ups2 and Ups3 protein import is mediated by another mitochondrial intermembrane space protein, Mdm35p.
      Title: Mdm35p imports Ups proteins into the mitochondrial intermembrane space by functional complex formation.
    2. The authors identified Mdm35, a member of the twin Cx9C protein family, as a novel interaction partner of Ups1 and Ups2.
      Title: Regulation of mitochondrial phospholipids by Ups1/PRELI-like proteins depends on proteolysis and Mdm35.
    3. Data report that two homologous intermembrane space proteins, Ups1p and Ups2p, control cardiolipin metabolism and affect the assembly state of TIM23 and its association with PAM in an opposing manner.
      Title: Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria.
    4. deletion strains, ylr193cDelta/ylr193cDelta, yor305wDelta/yor305wDelta, and ypr170cDelta/ypr170cDelta, mate at very low frequencies with haploids of either or both MATa/MATalpha mating types.
      Title: Single-gene deletions that restore mating competence to diploid yeast.
    5. The UPS1 protein is a novel mitochondrial protein required for the unique processing of Mgm1p and for normal mitochondrial shape.
      Title: Ups1p, a conserved intermembrane space protein, regulates mitochondrial shape and alternative topogenesis of Mgm1p.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:31463 BioGRID:33282 ACB1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:31569 ACO1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32269 ADR1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36750 AFG3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33177 AFT1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31092 AGP3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36839 AIM11    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31161 AIM13    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35332 AIM36    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36633 AIM46    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36117 ALD6    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32814 ALG1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32621 ALG3    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35570 ALP1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33980 APE2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34950 APQ12    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36129 ARL3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32606 ATP1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33581 ATP12    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35059 ATP18    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32350 ATP5    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35580 ATX1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32608 BRN1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31121 BST1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:32236 CDC1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33832 CDC11    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32038 CDC7    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:32731 CDS1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33405 CHO2    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:33357 CLD1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32813 CMD1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:31772 CNE1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35773 COG5    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34396 COQ10    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35867 COQ2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33065 COX13    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36549 COX23    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36483 COX6    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35852 CPR8    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31919 CRD1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32737 CSG2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31639 CSR1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32743 CST26    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:34954 CST6    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:33997 CTK1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:31945 CYK3    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:36013 DAP1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34156 DBP7    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31753 DEP1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31273 DNM1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32195 DOP1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36868 DSE1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35690 EAF7    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36770 EDC2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36384 EFM1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32201 EKI1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36079 ELP4    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35079 ERG13    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35380 ERG2    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:33592 ERG20    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:33244 ERG26    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31331 ERG3    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35186 ERG5    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35161 ERG6    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:33534 ERV29    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32729 ETR1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:32742 FAT1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34927 FIS1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31661 FLD1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34857 FLX1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36078 FMP30    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32877 FZO1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35487 GAS1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:34370 GAS5    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31779 GEM1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34600 GEP3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36533 GEP4    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33226 GET1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36828 GET2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36728 GIM4    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36045 GIP3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33130 GPG1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33666 GWT1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35473 HER2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33831 HOC1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35364 HSC82    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:34392 HTZ1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33026 HXK2    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:36695 HYP2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34378 IFM1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33874 ILM1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:31691 IMD3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33650 IME2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33674 IML2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34293 INO4    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:32127 IPT1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34321 IRA2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35248 IRC21    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:34300 ITR2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31297 IZH3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35610 JJJ1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:33852 JJJ3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33490 KEL2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32117 LCB2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33622 LCB3    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35517 LEM3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33237 LEU1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33632 LSM1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35819 LST8    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32115 MAK21    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32883 MBA1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33890 MCM22    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31983 MDH3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35943 MDL2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31756 MDM10    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34395 MDM12    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36628 MDM31    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34080 MDM35    BioGRID  PubMed Affinity Capture-Western; Co-fractionation; Positive Genetic; Synthetic Rescue 
    BioGRID:31463 BioGRID:34373 MDM38    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34625 MGE1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34606 MGM1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33900 MGM101    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33047 MIG2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34715 MIP1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32788 MIS1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34843 MLP2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34663 MOD5    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35245 MOT3    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:33739 MPS3    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35847 MRPL50    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35012 MRS1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36223 MSF1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35750 MSK1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31955 MSS2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33264 MTL1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33004 MTO1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31731 MTW1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33129 NAB2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:31463 BioGRID:36322 NCA2    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:31976 NDE2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31275 NOC3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34002 OCT1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32369 OMS1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33829 OPI3    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:32764 ORC2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32126 PAA1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32540 PAC11    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34196 PAM17    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:31463 BioGRID:31281 PAM18    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31052 PAT1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:34745 PDE2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32381 PEP7    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33737 PET130    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35822 PET8    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35198 PEX12    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33381 PEX4    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33380 PHB1    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:31463 BioGRID:33483 PHB2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36772 PHM8    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35726 PHO23    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35082 PHO84    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33223 PIB2    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:32953 POP4    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35445 PPA2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31208 PRE4    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35494 PRE5    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:32019 PRM7    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33195 PRM8    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33555 PRP21    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36350 PRP4    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35659 PSD1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:32048 PTC1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:36510 PTC7    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:36623 PTH1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31410 PUT1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31190 QCR6    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33593 QCR8    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31019 RBK1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35250 RCO1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36679 RML2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35511 RPD3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34872 RPI1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34225 RPL40B    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:32035 RPN4    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:31110 RPO41    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31980 RPP1A    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31619 RSC2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34140 RSC4    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35444 RSN1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36869 RSP5    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35999 RTC6    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32600 RTG3    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35630 RTT106    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:32449 RVS167    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:33953 SAC1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35939 SAM3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35441 SAP30    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32738 SCO1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36865 SCS2    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35451 SCS7    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33995 SDH3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34908 SDS3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35013 SEC11    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:32648 SEC17    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31536 SEC22    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36098 SEN54    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31248 SFI1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:30971 SGF29    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:34410 SGT2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32666 SHE1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34400 SIN3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32007 SLC1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:32144 SLU7    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31404 SLX4    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31463 BioGRID:36861 SLX8    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32242 SLY1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32561 SMT3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32529 SNF1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33136 SNF4    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34972 SNL1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35270 SNO1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32484 SNX41    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35241 SOV1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31463 BioGRID:33938 SPE1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36008 SPT14    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:32454 SPT3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34222 SRL3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33665 SRS2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33797 SSC1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36075 SSE1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35855 SSK2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33873 STE24    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:30951 STE50    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31320 STU2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35757 SUN4    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32349 SUR2    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:31632 SUR4    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:33091 SUT1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31755 SWC3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32926 SWC5    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32391 SWR1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31013 SYP1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35405 TAF7    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35069 TCB3    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:32111 TGL2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31033 THR4    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33434 TIM13    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34685 TIM18    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31828 TIM22    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35842 TIM23    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33891 TIM8    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34979 TIR3    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34385 TLG2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34854 TMA108    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33511 TNA1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35696 TOM22    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36300 TOM5    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34446 TOM6    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35753 TOM7    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33823 TOR1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35981 TPK2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33971 TPK3    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:36148 TRM44    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32961 TSC10    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:33437 TYS1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35193 UBC7    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36719 UBC8    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32968 UBX7    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33261 UGA1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36157 ULP1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32257 UME6    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31441 UPS2    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression; Synthetic Growth Defect; Synthetic Rescue 
    BioGRID:31463 BioGRID:32239 UPS3    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression; Synthetic Growth Defect 
    BioGRID:31463 BioGRID:35140 USA1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34174 UTH1    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:34971 VID28    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32828 VMA2    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35831 VPS27    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36346 VPS4    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32537 VPS72    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31363 XDJ1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:32933 YBR238C    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31944 YDL119C    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31906 YDL157C    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31171 YFR018C    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31203 YFR045W    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33211 YGL036W    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:33255 YGR012W    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35420 YHM2    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:31520 YLR253W    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:31556 YLR290C    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31609 YLR346C    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36201 YME1    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35482 YME2    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35189 YMR018W    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35330 YMR155W    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35337 YMR160W    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:35815 YNL010W    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:34426 YOR022C    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36072 YPL109C    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:36281 YPR114W    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:33046 YPT32    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35731 YPT53    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:31529 YPT6    BioGRID  PubMed Positive Genetic 
    BioGRID:31463 BioGRID:33951 YRA2    BioGRID  PubMed Negative Genetic 
    BioGRID:31463 BioGRID:35264 YTA12    BioGRID  PubMed Negative Genetic 
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    General gene information

    Homology

    • Homologs of the UPS1 gene: The UPS1 gene is conserved in human, chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.pombe, S.cerevisiae, K.lactis, and E.gossypii.

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    cardiolipin metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    extrinsic to mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    mitochondrial intermembrane space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    mitochondrial intermembrane space IEA
    Inferred from Electronic Annotation
    more info
    		  
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Names
    Ups1p
    NP_013294.1
    • Mitochondrial intermembrane space protein that regulates mitochondrial cardiolipin levels, null has defects in Mgm1p processing, integrity of mitochondrial inner membrane complexes, and mitochondrial morphology; ortholog of human PRELI
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5

      Range
      540009..540536, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182080.1 → NP_013294.1  Ups1p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q05776
      Conserved Domains (1) summary
      pfam04707
      Location:16 – 170
      Blast Score: 485
      PRELI; PRELI-like family
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006945.2 DAA09512.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    Q05776.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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