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CBF5 pseudouridine synthase CBF5 [ Saccharomyces cerevisiae S288c ]

Gene ID: 850872, updated on 18-Feb-2015
Gene symbol
CBF5
Gene description
pseudouridine synthase CBF5
Primary source
SGD:S000004165
Locus tag
YLR175W
Gene type
protein coding
RNA name
pseudouridine synthase CBF5
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See CBF5 in MapViewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (506134..507585)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene isocitrate dehydrogenase (NADP(+)) IDP2 Neighboring gene Rfx1p Neighboring gene hypothetical protein

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA binding IEA
Inferred from Electronic Annotation
more info
 
isomerase activity IEA
Inferred from Electronic Annotation
more info
 
mRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to pseudouridine synthase activity IDA
Inferred from Direct Assay
more info
PubMed 
pseudouridine synthase activity IEA
Inferred from Electronic Annotation
more info
 
pseudouridine synthase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
pseudouridine synthase activity ISA
Inferred from Sequence Alignment
more info
PubMed 
Process Evidence Code Pubs
RNA modification IEA
Inferred from Electronic Annotation
more info
 
RNA processing IEA
Inferred from Electronic Annotation
more info
 
box H/ACA snoRNA 3'-end processing IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell division IEA
Inferred from Electronic Annotation
more info
 
mRNA pseudouridine synthesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic nuclear division IEA
Inferred from Electronic Annotation
more info
 
pseudouridine synthesis IEA
Inferred from Electronic Annotation
more info
 
rRNA processing IEA
Inferred from Electronic Annotation
more info
 
rRNA processing IMP
Inferred from Mutant Phenotype
more info
PubMed 
rRNA pseudouridine synthesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
 
snRNA pseudouridine synthesis IDA
Inferred from Direct Assay
more info
PubMed 
snRNA pseudouridine synthesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
90S preribosome IDA
Inferred from Direct Assay
more info
PubMed 
box H/ACA snoRNP complex IPI
Inferred from Physical Interaction
more info
PubMed 
chromosome IEA
Inferred from Electronic Annotation
more info
 
chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
microtubule IEA
Inferred from Electronic Annotation
more info
 
nucleolus IC
Inferred by Curator
more info
PubMed 
nucleolus IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
Names
pseudouridine synthase CBF5
NP_013276.1
  • Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs; acts on large and small rRNAs, on snRNA U2, and on some mRNAs; mutations in human ortholog dyskerin cause the disorder dyskeratosis congenita; small nucleolar ribonucleoprotein particles are also known as snoRNPs

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    506134..507585
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182062.1NP_013276.1  pseudouridine synthase CBF5 [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_013276.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P33322
    Conserved Domains (4) summary
    cd02572
    Location:58240
    PseudoU_synth_hDyskerin; Pseudouridine synthase, human dyskerin like
    pfam01472
    Location:267340
    PUA; PUA domain
    pfam08068
    Location:1876
    DKCLD; DKCLD (NUC011) domain
    TIGR00425
    Location:26351
    Probable_tRNA_pseudouridine_synthase_B; rRNA pseudouridine synthase, putative