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    AHP1 Ahp1p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 850799, updated on 6-May-2012
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    Summary

    Gene symbol
    AHP1
    Gene description
    Ahp1p
    Primary source
    SGD:S000004099
    Locus tag
    YLR109W
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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    Genomic context

    Location :
    chromosome: XII
    Sequence :
    Chromosome: XII; NC_001144.5 (368781..369311)
    See AHP1 in MapViewer

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene hypothetical protein Neighboring gene Ccw12p Neighboring gene Hog1p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. La-motif-dependent mRNA association with Slf1 promotes copper detoxification in yeast. Schenk L, et al. RNA, 2012 Mar. PMID 22271760.
    2. Sites of ubiquitin attachment in Saccharomyces cerevisiae. Starita LM, et al. Proteomics, 2012 Jan. PMID 22106047.
    3. Transcriptome-wide binding sites for components of the Saccharomyces cerevisiae non-poly(A) termination pathway: Nrd1, Nab3, and Sen1. Creamer TJ, et al. PLoS Genet, 2011 Oct. PMID 22028667.
    4. An integrated approach to characterize genetic interaction networks in yeast metabolism. Szappanos B, et al. Nat Genet, 2011 May 29. PMID 21623372.
    5. A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis. Ziv I, et al. Mol Cell Proteomics, 2011 May. PMID 21427232.

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    NC_001144.3 NP_014232.1 SKO1    BIND  PubMed Sko1 associates with Ahp1 promoter. 
    NP_013210.1 NP_012837.1 SRX1    BIND  PubMed Srx1 co-purified with Ahp1 
    BioGRID:31382 BioGRID:31382 AHP1    BioGRID  PubMed Reconstituted Complex 
    BioGRID:31382 BioGRID:35876 BRE5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:32482 CAD1    BioGRID  PubMed Affinity Capture-Western; Two-hybrid 
    BioGRID:31382 BioGRID:35315 CIN4    BioGRID  PubMed Two-hybrid 
    BioGRID:31382 BioGRID:34955 CKA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:32835 CKS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:34635 ESA1    BioGRID  PubMed Negative Genetic 
    BioGRID:31382 BioGRID:36877 GLC7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:34342 GPD2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:34105 GPX1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31382 BioGRID:32939 GPX2    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31382 BioGRID:36176 HAT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:35028 HYR1    BioGRID  PubMed Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:31382 BioGRID:33161 LIF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:31846 MGT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:33129 NAB2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:31382 BioGRID:35588 NRD1    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:31382 BioGRID:35176 PLB2    BioGRID  PubMed Positive Genetic 
    BioGRID:31382 BioGRID:32635 PRX1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31382 BioGRID:35527 RFA2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:34547 RPB2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:31382 BioGRID:36634 RPN10    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:31152 RPN11    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:31602 RPP0    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:32420 SEM1    BioGRID  PubMed Negative Genetic 
    BioGRID:31382 BioGRID:31689 SEN1    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:31382 BioGRID:35234 SEN15    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:32566 SLF1    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:31382 BioGRID:31404 SLX4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:36586 SPO12    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:32572 SPS2    BioGRID  PubMed Negative Genetic 
    BioGRID:31382 BioGRID:30946 SRO9    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:31382 BioGRID:35627 SSB2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:32225 SUP35    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:35744 TPM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:31318 TRX1    BioGRID  PubMed Affinity Capture-MS; Two-hybrid 
    BioGRID:31382 BioGRID:33462 TRX2    BioGRID  PubMed Affinity Capture-MS; Two-hybrid 
    BioGRID:31382 BioGRID:35141 TSA1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31382 BioGRID:32508 TSA2    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31382 BioGRID:35193 UBC7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:31215 UBI4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:36901 UBP3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:34984 URM1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:31382 BioGRID:32428 XRS2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:33616 YAK1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31382 BioGRID:36568 YCK1    BioGRID  PubMed Affinity Capture-MS 
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    General gene information

    Pathways from BioSystems

    • Sulfur relay system, organism-specific biosystem (from KEGG)
      Sulfur relay system, organism-specific biosystemUbiquitin and ubiquitin-like proteins (Ubls) are signalling messengers that control many cellular functions, such as cell proliferation, apoptosis, and DNA repair. It is suggested that Ub-protein mod...
    • Sulfur relay system, conserved biosystem (from KEGG)
      Sulfur relay system, conserved biosystemUbiquitin and ubiquitin-like proteins (Ubls) are signalling messengers that control many cellular functions, such as cell proliferation, apoptosis, and DNA repair. It is suggested that Ub-protein mod...

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    antioxidant activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    peroxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    peroxiredoxin activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    thioredoxin peroxidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    thioredoxin peroxidase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    thioredoxin peroxidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    cell redox homeostasis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    cell redox homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    cellular response to oxidative stress IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
    		  
    response to metal ion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    plasma membrane enriched fraction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
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    General protein information

    Names
    Ahp1p
    NP_013210.1
    • Thiol-specific peroxiredoxin, reduces hydroperoxides to protect against oxidative damage; function in vivo requires covalent conjugation to Urm1p
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5

      Range
      368781..369311
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181996.1 → NP_013210.1  Ahp1p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P38013
      Conserved Domains (1) summary
      cd03013
      Location:5 – 174
      Blast Score: 425
      PRX5_like; Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5 ...
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006945.2 DAA09425.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38013.4 GenPept
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    Additional Links

    Gene LinkOut

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