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    RPL10 Rpl10p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 850764, updated on 31-Jan-2012
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    Summary

    Gene symbol
    RPL10
    Gene description
    Rpl10p
    Primary source
    SGD:S000004065
    Locus tag
    YLR075W
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    GRC5; QSR1
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    Genomic context

    Sequence :
    Chromosome: XII; NC_001144.5 (282927..283592)
    See RPL10 in MapViewer

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Rfu1p Neighboring gene Bud20p Neighboring gene Fmp25p Neighboring gene Bos1p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Sites of ubiquitin attachment in Saccharomyces cerevisiae. Starita LM, et al. Proteomics, 2012 Jan. PMID 22106047.
    2. Assembly of Saccharomyces cerevisiae 60S ribosomal subunits: role of factors required for 27S pre-rRNA processing. Sahasranaman A, et al. EMBO J, 2011 Sep 16. PMID 21926967.
    3. Dynamics of the putative RNA helicase Spb4 during ribosome assembly in Saccharomyces cerevisiae. García-Gómez JJ, et al. Mol Cell Biol, 2011 Oct. PMID 21825077.
    4. A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis. Ziv I, et al. Mol Cell Proteomics, 2011 May. PMID 21427232.
    5. Not4 E3 ligase contributes to proteasome assembly and functional integrity in part through Ecm29. Panasenko OO, et al. Mol Cell Biol, 2011 Apr. PMID 21321079.

    See all (51) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. mutant Rpl10 proteins were engineered to be unable to bind to the ribosome accumulated in the nucleus
      Title: Mutational analysis of the ribosomal protein Rpl10 from yeast.
    2. correct loading of Rpl10p into 60S subunits is required for the release of Nmd3p from subunits by Lsg1p
      Title: Release of the export adapter, Nmd3p, from the 60S ribosomal subunit requires Rpl10p and the cytoplasmic GTPase Lsg1p.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:31349 BioGRID:31422 ACS2    BioGRID  PubMed Two-hybrid 
    BioGRID:31349 BioGRID:32740 ATP3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35876 BRE5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:34947 CBR1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32241 CCT6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:36484 CIC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35713 DBP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:36448 DED81    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35002 DSN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:36392 ECM29    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32942 ENP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:31759 ERP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32422 ESF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32186 FIN1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:31349 BioGRID:31730 FUN12    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35584 GIS2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-RNA 
    BioGRID:31349 BioGRID:31894 GLT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32710 HHF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35695 KRE33    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:33150 LSG1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:31349 BioGRID:34898 LYS12    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:31862 LYS20    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32788 MIS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:34123 MRT4    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:31349 BioGRID:35703 NAF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35959 NEW1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:36604 NMD3    BioGRID  PubMed Affinity Capture-Western; Dosage Rescue; Synthetic Rescue 
    BioGRID:31349 BioGRID:35878 NOG2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32040 NOP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35715 NOP15    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35101 ORC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:34393 PLB3    BioGRID  PubMed Two-hybrid 
    BioGRID:31349 BioGRID:33087 PMR1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32003 PSA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:31190 QCR6    BioGRID  PubMed Synthetic Lethality 
    BioGRID:31349 BioGRID:33033 RAI1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:36631 RIX1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:31349 BioGRID:32148 RLI1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:34212 RPF2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:33327 RPL11B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:36675 RPL12A    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:31349 BioGRID:32476 RPL12B    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:31349 BioGRID:31979 RPL13A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35318 RPL13B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:36424 RPL14B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:31303 RPL15A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:34858 RPL16A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35754 RPL16B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:33959 RPL17A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:33584 RPL17B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:34281 RPL18A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35537 RPL18B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32671 RPL19B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35965 RPL1A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:33117 RPL1B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35421 RPL20A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:34700 RPL20B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:33215 RPL24A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:34248 RPL25    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:33279 RPL26B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32524 RPL27B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:33147 RPL28    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:31189 RPL29    BioGRID  PubMed Synthetic Lethality 
    BioGRID:31349 BioGRID:31187 RPL2A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:34970 RPL2B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:34462 RPL3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:33216 RPL30    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:31986 RPL31A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:34627 RPL33B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:31925 RPL35B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35372 RPL36A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35913 RPL36B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:36574 RPL42B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32733 RPL4A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35068 RPL6A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:31706 RPL6B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:33174 RPL7A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35986 RPL7B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:36389 RPL8A    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:31349 BioGRID:31269 RPL8B    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:31349 BioGRID:36458 RPN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:31152 RPN11    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:31602 RPP0    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32443 RPP2B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32075 RPS11A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32750 RPS11B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32119 RPS13    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:31014 RPS14A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:31978 RPS16B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32502 RPS17B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32505 RPS18A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:31700 RPS1A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35103 RPS1B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:33573 RPS22A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:36817 RPS24A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35653 RPS3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:31553 RPS30A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:36637 RPS4B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:33879 RPS5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:36091 RPS6A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32879 RPS6B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:34494 RPS7A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35728 RPS7B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32629 RPS8A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32887 RPS9B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:34513 RPT5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32472 RRP17    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35990 RSA1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:31349 BioGRID:31451 SAM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35304 SAS2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:33676 SCP160    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:36096 SEC16    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:36353 SEC23    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:31850 SEC31    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32132 SED1    BioGRID  PubMed Dosage Rescue; Two-hybrid 
    BioGRID:31349 BioGRID:35775 SFB2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:36334 SGV1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:31147 SPB4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:33767 SPC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35004 SQT1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Dosage Rescue; Two-hybrid 
    BioGRID:31349 BioGRID:36498 SSF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:36496 SSZ1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:31419 STM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:32961 TSC10    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:31215 UBI4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:36901 UBP3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:34118 URB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:33647 UTP10    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:35261 YMR086W    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31349 BioGRID:33531 YOR1    BioGRID  PubMed Affinity Capture-MS 
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    General gene information

    Homology

    • Homologs of the RPL10 gene: The RPL10 gene is conserved in human, chimpanzee, dog, mouse, rat, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, and rice.

    Pathways from BioSystems

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    cytoplasmic translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    ribosomal large subunit assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    translational termination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    cytosolic large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    intracellular IEA
    Inferred from Electronic Annotation
    more info
    		  
    ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Names
    Rpl10p
    NP_013176.1
    • Protein component of the large (60S) ribosomal subunit, responsible for joining the 40S and 60S subunits; regulates translation initiation; has similarity to rat L10 ribosomal protein and to members of the QM gene family
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5

      Range
      282927..283592
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181962.1 → NP_013176.1  Rpl10p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P41805
      Conserved Domains (1) summary
      cd01433
      Location:43 – 166
      Blast Score: 239
      Ribosomal_L16_L10e; Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with ...
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006945.2 DAA09392.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    P41805.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

      Supplemental Content