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    GCN20 Gcn20p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 850561, updated on 4-Feb-2012

    Summary

    Gene symbol
    GCN20
    Gene description
    Gcn20p
    Primary source
    SGD:S000001905
    Locus tag
    YFR009W
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces

    Genomic context

    Sequence :
    Chromosome: VI; NC_001138.5 (162488..164746)
    See GCN20 in MapViewer

    Chromosome VI - NC_001138.5Genomic Context describing neighboring genes Neighboring gene Far7p Neighboring gene tRNA Neighboring gene Ubp6p Neighboring gene Aim13p

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:31159 BioGRID:35858 ABZ1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:35498 ADH6    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:33709 AIM22    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36440 ARD1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:32183 ARO1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:31746 ATS1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36642 BAT1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:35876 BRE5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:33497 BRF1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36231 BRR1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:35041 CAC2    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:32241 CCT6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:33832 CDC11    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:32038 CDC7    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36803 CEM1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:33227 CKB1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:34441 CKB2    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement 
    BioGRID:31159 BioGRID:34084 CSE4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:36001 CTI6    BioGRID  PubMed Positive Genetic 
    BioGRID:31159 BioGRID:36448 DED81    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:32462 DIT2    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:33952 DOA1    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement 
    BioGRID:31159 BioGRID:35467 DSS1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36384 EFM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:33453 ELP2    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36095 ELP3    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:31159 BioGRID:36079 ELP4    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:35691 FPR1    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement 
    BioGRID:31159 BioGRID:32061 GAL3    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement 
    BioGRID:31159 BioGRID:33062 GCN1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Phenotypic Suppression; Positive Genetic; Two-hybrid 
    BioGRID:31159 BioGRID:32336 GCN2    BioGRID  PubMed Affinity Capture-Western; Dosage Rescue; Reconstituted Complex 
    BioGRID:31159 BioGRID:33503 GCN5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:34030 GFA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:33469 GPI1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:34313 HAL9    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:32710 HHF1    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:31159 BioGRID:35364 HSC82    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31159 BioGRID:35923 HSP82    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31159 BioGRID:36695 HYP2    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:31133 IES1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:34321 IRA2    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:34996 IST3    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:33726 KAR2    BioGRID  PubMed Positive Genetic 
    BioGRID:31159 BioGRID:31063 KIN82    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:32092 KRS1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36517 KSP1    BioGRID  PubMed Biochemical Activity 
    BioGRID:31159 BioGRID:31506 LIP2    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:31697 LSM3    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:35681 LSM7    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:31862 LYS20    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:34102 MAE1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:35532 MCK1    BioGRID  PubMed Biochemical Activity 
    BioGRID:31159 BioGRID:34615 MCT1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:35104 MFT1    BioGRID  PubMed Positive Genetic 
    BioGRID:31159 BioGRID:36223 MSF1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:31641 NAM2    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36732 NOP16    BioGRID  PubMed Phenotypic Suppression; Positive Genetic 
    BioGRID:31159 BioGRID:32489 NPL3    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:34078 OAR1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36918 PAB1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:32540 PAC11    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36931 PDA1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:32867 POP7    BioGRID  PubMed Positive Genetic 
    BioGRID:31159 BioGRID:32680 POP8    BioGRID  PubMed Positive Genetic 
    BioGRID:31159 BioGRID:36035 PPT2    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:33383 PRE9    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:34217 PRP16    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36350 PRP4    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:32003 PSA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:35973 PUS1    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement 
    BioGRID:31159 BioGRID:34634 PUS7    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36692 RAD23    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36924 RAD3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:36841 RAD51    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:34186 RHO4    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36195 RLF2    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36153 RMI1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:33610 RPA34    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:34723 RPA43    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:34547 RPB2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:35511 RPD3    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:33117 RPL1B    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:32617 RPL23A    BioGRID  PubMed Positive Genetic 
    BioGRID:31159 BioGRID:33574 RPL39    BioGRID  PubMed Co-fractionation 
    BioGRID:31159 BioGRID:36634 RPN10    BioGRID  PubMed Affinity Capture-MS; Negative Genetic 
    BioGRID:31159 BioGRID:31152 RPN11    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:31680 RPN13    BioGRID  PubMed Positive Genetic 
    BioGRID:31159 BioGRID:32750 RPS11B    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:35143 RPS18B    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:33363 RPS23A    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36637 RPS4B    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:32047 RPT2    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:31829 RRI1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:30952 RRP7    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:31307 RSC58    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:35999 RTC6    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31159 BioGRID:34334 RTG1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:32600 RTG3    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:34476 RTS2    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:35927 RVB2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:32801 RXT2    BioGRID  PubMed Phenotypic Suppression; Positive Genetic 
    BioGRID:31159 BioGRID:31451 SAM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:31198 SAP155    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:35441 SAP30    BioGRID  PubMed Positive Genetic 
    BioGRID:31159 BioGRID:35568 SEC2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:32221 SEC7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:32420 SEM1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:31333 SHM2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:31657 SKI2    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:32007 SLC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:32144 SLU7    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:33323 SLX9    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36267 SNT309    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:35241 SOV1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31159 BioGRID:32345 SSD1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36498 SSF1    BioGRID  PubMed Positive Genetic 
    BioGRID:31159 BioGRID:35801 SSN8    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:31710 SST2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:32211 SSY1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36987 SUS1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:36856 SWI4    BioGRID  PubMed Positive Genetic 
    BioGRID:31159 BioGRID:32391 SWR1    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement 
    BioGRID:31159 BioGRID:36052 TAF14    BioGRID  PubMed Positive Genetic 
    BioGRID:31159 BioGRID:34854 TMA108    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31159 BioGRID:34489 TMA46    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:31159 BioGRID:35081 TUB3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:36238 UBA3    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:31215 UBI4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:35647 UBP10    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:36901 UBP3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:36043 UME1    BioGRID  PubMed Positive Genetic 
    BioGRID:31159 BioGRID:34191 UTP30    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement 
    BioGRID:31159 BioGRID:31859 VMA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:31214 VPS13    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:31788 VPS8    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:31878 YDL233W    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:33486 YHB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:31159 BioGRID:31562 YHC1    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:31421 YLR152C    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:35705 YNL122C    BioGRID  PubMed Negative Genetic 
    BioGRID:31159 BioGRID:34609 YOR214C    BioGRID  PubMed Negative Genetic 

    General gene information

    Homology

    • Homologs of the GCN20 gene: The GCN20 gene is conserved in human, chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana, and rice.

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    ATPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    nucleoside-triphosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    ATP catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of translational elongation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of translational elongation IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    cytosolic ribosome IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Names
    Gcn20p
    NP_116664.1
    • Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn1p; proposed to stimulate Gcn2p activation by an uncharged tRNA

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001138.5

      Range
      162488..164746
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179974.1NP_116664.1  Gcn20p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P43535
      Conserved Domains (4) summary
      COG0488
      Location:198741
      Blast Score: 1197
      Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]
      cd03221
      Location:532724
      Blast Score: 375
      ABCF_EF-3; ABCF_EF-3 Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated ...
      pfam12848
      Location:438519
      Blast Score: 224
      ABC_tran_2; ABC transporter
      cl09099
      Location:199263
      Blast Score: 141
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006940.2 DAA12449.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    P43535.1 GenPept

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