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PAT1 Pat1p [ Saccharomyces cerevisiae S288c ]

Gene ID: 850440, updated on 6-Jul-2014
Gene symbol
PAT1
Gene description
Pat1p
Primary source
SGD:S000000673
Locus tag
YCR077C
Gene type
protein coding
RNA name
Pat1p
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
MRT1
See PAT1 in MapViewer
Location:
chromosome: III
Exon count :
1
Sequence:
Chromosome: III; NC_001135.5 (250238..252628, complement)

Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene Fub1p Neighboring gene Ptc6p Neighboring gene Srb8p

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Decapping complex, organism-specific biosystem (from KEGG)
    Decapping complex, organism-specific biosystemStructural complex; Genetic information processing; RNA processing
  • Decapping complex, conserved biosystem (from KEGG)
    Decapping complex, conserved biosystemStructural complex; Genetic information processing; RNA processing
  • RNA degradation, organism-specific biosystem (from KEGG)
    RNA degradation, organism-specific biosystemThe correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay e...
  • RNA degradation, conserved biosystem (from KEGG)
    RNA degradation, conserved biosystemThe correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay e...
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
RNA binding IEA
Inferred from Electronic Annotation
more info
 
chromatin binding IDA
Inferred from Direct Assay
more info
 
mRNA binding IDA
Inferred from Direct Assay
more info
 
Process Evidence Code Pubs
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell division IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic mRNA processing body assembly IGI
Inferred from Genetic Interaction
more info
PubMed 
cytoplasmic mRNA processing body assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
deadenylation-dependent decapping of nuclear-transcribed mRNA IMP
Inferred from Mutant Phenotype
more info
PubMed 
deadenylation-dependent decapping of nuclear-transcribed mRNA IPI
Inferred from Physical Interaction
more info
PubMed 
formation of translation preinitiation complex IMP
Inferred from Mutant Phenotype
more info
 
mRNA processing IEA
Inferred from Electronic Annotation
more info
 
negative regulation of translational initiation IDA
Inferred from Direct Assay
more info
 
negative regulation of translational initiation IMP
Inferred from Mutant Phenotype
more info
 
regulation of translation IEA
Inferred from Electronic Annotation
more info
 
regulation of translational initiation IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of translational initiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic mRNA processing body IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasmic mRNA processing body IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic mRNA processing body IMP
Inferred from Mutant Phenotype
more info
PubMed 
cytoplasmic stress granule IDA
Inferred from Direct Assay
more info
 
cytosolic small ribosomal subunit IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
Pat1p
NP_010002.3
  • Deadenylation-dependent mRNA-decapping factor; also required for faithful chromosome transmission, maintenance of rDNA locus stability, and protection of mRNA 3'-UTRs from trimming; associated with topoisomerase II; functionally linked to Pab1p; forms cytoplasmic foci upon DNA replication stress

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001135.5 

    Range
    250238..252628
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178786.2NP_010002.3  Pat1p [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_010002.3

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P25644
    Conserved Domains (1) summary
    pfam09770
    Location:1788
    Blast Score: 1950
    PAT1; Topoisomerase II-associated protein PAT1

Supplemental Content

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