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SLC43A1 solute carrier family 43 member 1 [ Homo sapiens (human) ]

Gene ID: 8501, updated on 12-May-2016
Official Symbol
SLC43A1provided by HGNC
Official Full Name
solute carrier family 43 member 1provided by HGNC
Primary source
HGNC:HGNC:9225
See related
Ensembl:ENSG00000149150 HPRD:07227; MIM:603733; Vega:OTTHUMG00000167030
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LAT3; PB39; POV1; R00504
Summary
SLC43A1 belongs to the system L family of plasma membrane carrier proteins that transports large neutral amino acids (Babu et al., 2003 [PubMed 12930836]).[supplied by OMIM, Mar 2008]
Orthologs
Location:
11q12.1
Exon count:
17
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 11 NC_000011.10 (57484531..57515719, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (57252004..57283192, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene RNA, 5S ribosomal pseudogene 341 Neighboring gene reticulon 4 receptor-like 2 Neighboring gene translocase of inner mitochondrial membrane 10 homolog (yeast) Neighboring gene smoothelin-like 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
amino acid transmembrane transporter activity TAS
Traceable Author Statement
more info
 
neutral amino acid transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
L-alpha-amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
amino acid transport TAS
Traceable Author Statement
more info
 
neutral amino acid transport IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
integral component of plasma membrane TAS
Traceable Author Statement
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 
Preferred Names
large neutral amino acids transporter small subunit 3
Names
L-type amino acid transporter 3
SLC43A1
prostate cancer overexpressed gene 1 protein
solute carrier family 43 (amino acid system L transporter), member 1
solute carrier family 43, member 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001198810.1NP_001185739.1  large neutral amino acids transporter small subunit 3

    See identical proteins and their annotated locations for NP_001185739.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AA040589, BC001639, BQ029981
    Consensus CDS
    CCDS7958.1
    UniProtKB/Swiss-Prot
    O75387
    UniProtKB/TrEMBL
    A0A024R4Y3
    Related
    ENSP00000435673, OTTHUMP00000234820, ENST00000528450, OTTHUMT00000392542
    Conserved Domains (1) summary
    cd06174
    Location:75219
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
  2. NM_003627.5NP_003618.1  large neutral amino acids transporter small subunit 3

    See identical proteins and their annotated locations for NP_003618.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AA040589, AB103033, BM147085, BQ029981
    Consensus CDS
    CCDS7958.1
    UniProtKB/Swiss-Prot
    O75387
    UniProtKB/TrEMBL
    A0A024R4Y3
    Related
    ENSP00000278426, OTTHUMP00000234819, ENST00000278426, OTTHUMT00000392541
    Conserved Domains (1) summary
    cd06174
    Location:75219
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p2 Primary Assembly

    Range
    57484531..57515719 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011545320.1XP_011543622.1  

    Conserved Domains (1) summary
    cd06174
    Location:91175
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
  2. XM_005274358.3XP_005274415.1  

    See identical proteins and their annotated locations for XP_005274415.1

    Conserved Domains (1) summary
    cd06174
    Location:91235
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
  3. XM_011545321.1XP_011543623.1  

    See identical proteins and their annotated locations for XP_011543623.1

  4. XM_011545322.1XP_011543624.1  

    See identical proteins and their annotated locations for XP_011543624.1

  5. XM_011545323.1XP_011543625.1  

    See identical proteins and their annotated locations for XP_011543625.1

RNA

  1. XR_950084.1 RNA Sequence

Alternate CHM1_1.1

Genomic

  1. NC_018922.2 Alternate CHM1_1.1

    Range
    57118296..57149440 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)