These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_003626.3 → NP_003617.1 liprin-alpha-1 isoform b
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) represents the longest transcript and it encodes the longer protein (isoform b).
- Source sequence(s)
-
AK124621, AW163189, CK902590, U22816
- Consensus CDS
-
CCDS31627.1
- UniProtKB/TrEMBL
-
B3KVS8
- UniProtKB/Swiss-Prot
-
Q13136
- Related
- ENSP00000253925, OTTHUMP00000235552, ENST00000253925, OTTHUMT00000393905
- Conserved Domains (6) summary
-
- COG1196
Location:58 – 409
Blast Score: 106
- Smc; Chromosome segregation ATPases [Cell division and chromosome partitioning]
- TIGR02168
Location:270 – 517
Blast Score: 197
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- cd09562
Location:875 – 942
Blast Score: 375
- SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
- cd09565
Location:962 – 1027
Blast Score: 384
- SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
- cd09568
Location:1047 – 1118
Blast Score: 373
- SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
- smart00454
Location:1048 – 1118
Blast Score: 116
- SAM; Sterile alpha motif.
-
NM_177423.2 → NP_803172.1 liprin-alpha-1 isoform a
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) differs in the 3' end, which includes a part of the coding region and 3' UTR, as compared to variant 2. The resulting protein (isoform a) has a distinct and shorter C-terminus, as compared to isoform b.
- Source sequence(s)
-
AW163189, BF352121, U22815
- Consensus CDS
-
CCDS31628.1
- UniProtKB/Swiss-Prot
-
Q13136
- Related
- ENSP00000374198, OTTHUMP00000235553, ENST00000389547, OTTHUMT00000393906
- Conserved Domains (6) summary
-
- COG1196
Location:58 – 409
Blast Score: 104
- Smc; Chromosome segregation ATPases [Cell division and chromosome partitioning]
- TIGR02168
Location:270 – 517
Blast Score: 196
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- cd09562
Location:875 – 942
Blast Score: 374
- SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
- cd09565
Location:962 – 1027
Blast Score: 383
- SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
- cd09568
Location:1047 – 1118
Blast Score: 373
- SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
- smart00454
Location:1048 – 1118
Blast Score: 115
- SAM; Sterile alpha motif.
RNA
-
NR_045286.1 RNA Sequence
- Description
- Transcript Variant: This variant (3) uses a different splice site in an internal exon and contains an alternate exon, compared to variant 2. This variant is represented as non-coding because the use of the 5'-most translational start codon, as used in variant 2, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AB209314, AW163189, CK902590, U22816
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000011.9 Reference GRCh37.p5 Primary Assembly
- Range
- 70116823..70230502
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000143.1 Alternate HuRef
- Range
- 66374591..66491554
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)