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IGSF21 immunoglobin superfamily, member 21 [ Homo sapiens (human) ]

Gene ID: 84966, updated on 26-Jun-2015
Official Symbol
IGSF21provided by HGNC
Official Full Name
immunoglobin superfamily, member 21provided by HGNC
Primary source
HGNC:HGNC:28246
See related
Ensembl:ENSG00000117154; HPRD:11309; Vega:OTTHUMG00000002432
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This gene encodes a protein which has two immunoglobulin (Ig) domains and is a member of the immunoglobulin superfamily. Proteins in this superfamily are usually found on or in cell membranes and act as receptors in immune response pathways. [provided by RefSeq, Sep 2011]
Orthologs
See IGSF21 in Epigenomics, MapViewer
Location:
1p36.13
Exon count:
12
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 1 NC_000001.11 (18107746..18378484)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (18434240..18704977)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376812 Neighboring gene uncharacterized LOC101927876 Neighboring gene uncharacterized LOC105376814 Neighboring gene uncharacterized LOC105376813 Neighboring gene kelch domain containing 7A Neighboring gene dynein, light chain, LC8-type 1 pseudogene 3

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer.
NHGRI GWA Catalog
Genome-wide meta-analysis for severe diabetic retinopathy.
NHGRI GWA Catalog
Products Interactant Other Gene Complex Source Pubs Description

Markers

Clone Names

  • FLJ41177, MGC15730

Gene Ontology Provided by GOA

Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
immunoglobulin superfamily member 21
Names
immunoglobulin superfamily member 21

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_027535.1 RefSeqGene

    Range
    5001..275738
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_032880.4NP_116269.3  immunoglobulin superfamily member 21 precursor

    See identical proteins and their annotated locations for NP_116269.3

    Status: REVIEWED

    Source sequence(s)
    AK075316, AL356101, BC007618
    Consensus CDS
    CCDS184.1
    UniProtKB/Swiss-Prot
    Q96ID5
    Related
    ENSP00000251296, OTTHUMP00000002532, ENST00000251296, OTTHUMT00000006924
    Conserved Domains (2) summary
    smart00410
    Location:353430
    IG_like; Immunoglobulin like
    cl11960
    Location:369432
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p2 Primary Assembly

    Range
    18107746..18378484
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011542319.1XP_011540621.1  

    Conserved Domains (2) summary
    smart00410
    Location:156233
    IG_like; Immunoglobulin like
    cl11960
    Location:172235
    Ig; Immunoglobulin domain
  2. XM_011542318.1XP_011540620.1  

    Conserved Domains (2) summary
    smart00410
    Location:347424
    IG_like; Immunoglobulin like
    cl11960
    Location:363426
    Ig; Immunoglobulin domain

Alternate CHM1_1.1

Genomic

  1. NC_018912.2 Alternate CHM1_1.1

    Range
    18543011..18814129
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)