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SLITRK2 SLIT and NTRK like family member 2 [ Homo sapiens (human) ]

Gene ID: 84631, updated on 3-Apr-2024

Summary

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Official Symbol
SLITRK2provided by HGNC
Official Full Name
SLIT and NTRK like family member 2provided by HGNC
Primary source
HGNC:HGNC:13449
See related
Ensembl:ENSG00000185985 MIM:300561; AllianceGenome:HGNC:13449
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CXorf1; CXorf2; SLITL1; TMEM257; XLID111
Summary
This gene encodes an integral membrane protein that contains two N-terminal leucine-rich repeats domains and contains C-terminal regions similar to neurotrophin receptors. The encoded protein may play a role in modulating neurite activity. Alternatively spliced transcript variants encoding the same protein have been described.[provided by RefSeq, Feb 2010]
Expression
Biased expression in brain (RPKM 6.9), spleen (RPKM 1.8) and 2 other tissues See more
Orthologs
mouse all
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Genomic context

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Location:
Xq27.3
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (145817829..145829856)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (144074860..144086894)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (144899347..144911374)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene TRMT1 pseudogene 1 Neighboring gene UFM1 pseudogene 1 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chrX:144884451-144885034 Neighboring gene uncharacterized LOC107985703 Neighboring gene MED14-independent group 3 enhancer GRCh37_chrX:144939449-144940648 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chrX:144947148-144947676 Neighboring gene microRNA 892c

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Identification of CXorf1, a novel intronless gene in Xq27.3, expressed in human hippocampus. Redolfi E, et al. DNA Cell Biol, 1998 Dec. PMID 9881668
  2. Slitrk1 is localized to excitatory synapses and promotes their development. Beaubien F, et al. Sci Rep, 2016 Jun 7. PMID 27273464, Free PMC Article
  3. Genome-wide association study of bipolar disorder in European American and African American individuals. Smith EN, et al. Mol Psychiatry, 2009 Aug. PMID 19488044, Free PMC Article
  4. Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia. Piton A, et al. Mol Psychiatry, 2011 Aug. PMID 20479760, Free PMC Article
  5. Slitrks control excitatory and inhibitory synapse formation with LAR receptor protein tyrosine phosphatases. Yim YS, et al. Proc Natl Acad Sci U S A, 2013 Mar 5. PMID 23345436, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Observational study of gene-disease association. (HuGE Navigator)
    Title: Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia.
  2. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
    Title: Genome-wide association study of bipolar disorder in European American and African American individuals.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Intellectual developmental disorder, X-linked 111
MedGen: C5829568 OMIM: 301107 GeneReviews: Not available
not available

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

HIV-1 interactions

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Replication interactions

Interaction Pubs
Knockdown of SLITRK2 (CXorf1) by shRNA library screening inhibits HIV-1 replication in cultured Jurkat T-cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • KIAA1854, MGC129912, MGC129913, MGC142160, MGC142164, DKFZp547F175, DKFZp451E1911

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in axonogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in axonogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of synapse assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of synapse assembly ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of presynapse assembly IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of presynapse assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of synapse organization IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of synapse organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in synaptic membrane adhesion IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in synaptic membrane adhesion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in GABA-ergic synapse IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in GABA-ergic synapse IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in dendrite IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in glutamatergic synapse IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in plasma membrane IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
  

General protein information

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Preferred Names
SLIT and NTRK-like protein 2
Names
slit and trk like gene 2
slit-like 1
transmembrane protein 257

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_016477.3 RefSeqGene

    Range
    5002..17029
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001144003.3 → NP_001137475.1  SLIT and NTRK-like protein 2 precursor

    See identical proteins and their annotated locations for NP_001137475.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All 9 variants encode the same protein.
    Source sequence(s)
    AK289732, AL109653, BM669862, DA239165
    Consensus CDS
    CCDS14680.1
    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156
    UniProtKB/TrEMBL
    Q6AI13
    Conserved Domains (7) summary
    smart00082
    Location:529 → 579
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:82 → 217
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:496 → 509
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:67 → 87
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:423 → 466
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:399 → 459
    LRR_8; Leucine rich repeat
    cl15307
    Location:216 → 252
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

  2. NM_001144004.3 → NP_001137476.1  SLIT and NTRK-like protein 2 precursor

    See identical proteins and their annotated locations for NP_001137476.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All 9 variants encode the same protein.
    Source sequence(s)
    AK289732, AL109653, BM669862, DA239165, DA412276
    Consensus CDS
    CCDS14680.1
    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156
    UniProtKB/TrEMBL
    Q6AI13
    Conserved Domains (7) summary
    smart00082
    Location:529 → 579
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:82 → 217
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:496 → 509
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:67 → 87
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:423 → 466
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:399 → 459
    LRR_8; Leucine rich repeat
    cl15307
    Location:216 → 252
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

  3. NM_001144005.3 → NP_001137477.1  SLIT and NTRK-like protein 2 precursor

    See identical proteins and their annotated locations for NP_001137477.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. All 9 variants encode the same protein.
    Source sequence(s)
    AK289732, AL109653, BM669862, DA234617, DA239165
    Consensus CDS
    CCDS14680.1
    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156
    UniProtKB/TrEMBL
    Q6AI13
    Conserved Domains (7) summary
    smart00082
    Location:529 → 579
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:82 → 217
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:496 → 509
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:67 → 87
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:423 → 466
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:399 → 459
    LRR_8; Leucine rich repeat
    cl15307
    Location:216 → 252
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

  4. NM_001144006.2 → NP_001137478.1  SLIT and NTRK-like protein 2 precursor

    See identical proteins and their annotated locations for NP_001137478.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. All 9 variants encode the same protein.
    Source sequence(s)
    AK096278, AK289732, AL109653, BC113011, BM669862
    Consensus CDS
    CCDS14680.1
    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156
    UniProtKB/TrEMBL
    Q6AI13
    Conserved Domains (7) summary
    smart00082
    Location:529 → 579
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:82 → 217
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:496 → 509
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:67 → 87
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:423 → 466
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:399 → 459
    LRR_8; Leucine rich repeat
    cl15307
    Location:216 → 252
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

  5. NM_001144008.2 → NP_001137480.1  SLIT and NTRK-like protein 2 precursor

    See identical proteins and their annotated locations for NP_001137480.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. All 9 variants encode the same protein.
    Source sequence(s)
    AK096278, AK289732, AL109653, BM669862, DA184412
    Consensus CDS
    CCDS14680.1
    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156
    UniProtKB/TrEMBL
    Q6AI13
    Conserved Domains (7) summary
    smart00082
    Location:529 → 579
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:82 → 217
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:496 → 509
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:67 → 87
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:423 → 466
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:399 → 459
    LRR_8; Leucine rich repeat
    cl15307
    Location:216 → 252
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

  6. NM_001144009.2 → NP_001137481.1  SLIT and NTRK-like protein 2 precursor

    See identical proteins and their annotated locations for NP_001137481.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 1. All 9 variants encode the same protein.
    Source sequence(s)
    AK096278, AK289732, AL109653, BM669862, DA496247
    Consensus CDS
    CCDS14680.1
    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156
    UniProtKB/TrEMBL
    Q6AI13
    Conserved Domains (7) summary
    smart00082
    Location:529 → 579
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:82 → 217
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:496 → 509
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:67 → 87
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:423 → 466
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:399 → 459
    LRR_8; Leucine rich repeat
    cl15307
    Location:216 → 252
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

  7. NM_001144010.2 → NP_001137482.1  SLIT and NTRK-like protein 2 precursor

    See identical proteins and their annotated locations for NP_001137482.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR compared to variant 1. All 9 variants encode the same protein.
    Source sequence(s)
    AK096278, AK289732, AL109653, BM669862, DA332123
    Consensus CDS
    CCDS14680.1
    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156
    UniProtKB/TrEMBL
    Q6AI13
    Conserved Domains (7) summary
    smart00082
    Location:529 → 579
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:82 → 217
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:496 → 509
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:67 → 87
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:423 → 466
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:399 → 459
    LRR_8; Leucine rich repeat
    cl15307
    Location:216 → 252
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

  8. NM_032539.5 → NP_115928.1  SLIT and NTRK-like protein 2 precursor

    See identical proteins and their annotated locations for NP_115928.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. All 9 variants encode the same protein.
    Source sequence(s)
    AK096278, AK289732, AL109653, BM669862, DA239165
    Consensus CDS
    CCDS14680.1
    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156
    UniProtKB/TrEMBL
    Q6AI13
    Related
    ENSP00000334374.5, ENST00000335565.6
    Conserved Domains (7) summary
    smart00082
    Location:529 → 579
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:82 → 217
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:496 → 509
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:67 → 87
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:423 → 466
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:399 → 459
    LRR_8; Leucine rich repeat
    cl15307
    Location:216 → 252
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    145817829..145829856
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005262343.4 → XP_005262400.1  SLIT and NTRK-like protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005262400.1

    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156
    UniProtKB/TrEMBL
    Q6AI13
    Conserved Domains (7) summary
    smart00082
    Location:529 → 579
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:82 → 217
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:496 → 509
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:67 → 87
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:423 → 466
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:399 → 459
    LRR_8; Leucine rich repeat
    cl15307
    Location:216 → 252
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

  2. XM_005262342.4 → XP_005262399.1  SLIT and NTRK-like protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005262399.1

    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156
    UniProtKB/TrEMBL
    Q6AI13
    Conserved Domains (7) summary
    smart00082
    Location:529 → 579
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:82 → 217
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:496 → 509
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:67 → 87
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:423 → 466
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:399 → 459
    LRR_8; Leucine rich repeat
    cl15307
    Location:216 → 252
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

  3. XM_005262345.4 → XP_005262402.1  SLIT and NTRK-like protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005262402.1

    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156
    UniProtKB/TrEMBL
    Q6AI13
    Conserved Domains (7) summary
    smart00082
    Location:529 → 579
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:82 → 217
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:496 → 509
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:67 → 87
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:423 → 466
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:399 → 459
    LRR_8; Leucine rich repeat
    cl15307
    Location:216 → 252
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

  4. XM_047442577.1 → XP_047298533.1  SLIT and NTRK-like protein 2 isoform X1

    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156
    Related
    ENSP00000359521.1, ENST00000370490.1

  5. XM_005262344.4 → XP_005262401.1  SLIT and NTRK-like protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005262401.1

    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156
    UniProtKB/TrEMBL
    Q6AI13
    Conserved Domains (7) summary
    smart00082
    Location:529 → 579
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:82 → 217
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:496 → 509
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:67 → 87
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:423 → 466
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:399 → 459
    LRR_8; Leucine rich repeat
    cl15307
    Location:216 → 252
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

  6. XM_047442578.1 → XP_047298534.1  SLIT and NTRK-like protein 2 isoform X1

    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    144074860..144086894
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054327986.1 → XP_054183961.1  SLIT and NTRK-like protein 2 isoform X1

    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156

  2. XM_054327985.1 → XP_054183960.1  SLIT and NTRK-like protein 2 isoform X1

    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156

  3. XM_054327990.1 → XP_054183965.1  SLIT and NTRK-like protein 2 isoform X1

    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156

  4. XM_054327987.1 → XP_054183962.1  SLIT and NTRK-like protein 2 isoform X1

    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156

  5. XM_054327988.1 → XP_054183963.1  SLIT and NTRK-like protein 2 isoform X1

    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156

  6. XM_054327989.1 → XP_054183964.1  SLIT and NTRK-like protein 2 isoform X1

    UniProtKB/Swiss-Prot
    A8K117, Q2KHN3, Q5JXB1, Q8NBC7, Q96JH3, Q9H156

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001144007.1: Suppressed sequence

    Description
    NM_001144007.1: This RefSeq was permanently suppressed because it appears to be partial and is redundant to another public RefSeq.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9H156.1 GenPept UniProtKB/Swiss-Prot:Q9H156

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