These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
Genomic
-
NG_029713.1 RefSeqGene
- Range
- 5001..12253
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_032431.2 → NP_115807.1 E3 ubiquitin-protein ligase synoviolin isoform a precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the shorter isoform (a).
- Source sequence(s)
-
AA864844, AL834262, BC030530
- Consensus CDS
-
CCDS8097.1
- UniProtKB/Swiss-Prot
-
Q86TM6
- Related
- ENSP00000294256, OTTHUMP00000230429, ENST00000294256, OTTHUMT00000385273
- Conserved Domains (2) summary
-
- cd00162
Location:291 – 333
Blast Score: 138
- RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
- COG5243
Location:10 – 334
Blast Score: 452
- HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
-
NM_172230.2 → NP_757385.1 E3 ubiquitin-protein ligase synoviolin isoform b precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses a different splice site than variant 1 and encodes the longer isoform (b).
- Source sequence(s)
-
AA864844, AL834262, BC030530
- Consensus CDS
-
CCDS31605.1
- UniProtKB/Swiss-Prot
-
Q86TM6
- Related
- ENSP00000366395, OTTHUMP00000230430, ENST00000377190, OTTHUMT00000385274
- Conserved Domains (2) summary
-
- cd00162
Location:291 – 333
Blast Score: 138
- RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
- COG5243
Location:10 – 334
Blast Score: 452
- HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000011.9 Reference GRCh37.p5 Primary Assembly
- Range
- 64894751..64902003, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000143.1 Alternate HuRef
- Range
- 61221343..61228995, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)